Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Size
small nodes:
protein of unknown 3D structure
protein of unknown 3D structure
large nodes:
some 3D structure is known or predicted
some 3D structure is known or predicted
Node Color
colored nodes:
query proteins and first shell of interactors
query proteins and first shell of interactors
white nodes:
second shell of interactors
second shell of interactors
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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Your Input:
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Neighborhood |
Gene Fusion |
Cooccurence |
Coexpression |
Experiments |
Databases |
Textmining |
[Homology] |
Score |
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 | KRTCAP3 | keratinocyte associated protein 3 (240 aa) | ||||||||||||
Predicted Functional Partners:
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 | SUPT7L | suppressor of Ty 7 (S. cerevisiae)-like (414 aa) |
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0.698 | ||||||||||
 | ZNF513 | zinc finger protein 513; Transcriptional regulator that plays a role in retinal development and maintenance (541 aa) |
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0.683 | ||||||||||
 | GTF3C2 | general transcription factor IIIC, polypeptide 2, beta 110kDa; Required for RNA polymerase III-mediated transcription. Component of TFIIIC that initiates transcription complex assembly on tRNA and is required for transcription of 5S rRNA and other stable nuclear and cytoplasmic RNAs. May play a direct role in stabilizing interactions of TFIIIC2 with TFIIIC1 (911 aa) |
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0.679 | ||||||||||
 | C2orf16 | chromosome 2 open reading frame 16 (1984 aa) |
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0.648 | ||||||||||
 | SLC4A1AP | solute carrier family 4 (anion exchanger), member 1, adaptor protein (796 aa) |
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0.644 | ||||||||||
 | LPPR2 | Lipid phosphate phosphatase-related protein type 2 (343 aa) |
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0.591 | ||||||||||
 | ZNF512 | zinc finger protein 512; May be involved in transcriptional regulation (567 aa) |
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0.584 | ||||||||||
 | KRTCAP2 | keratinocyte associated protein 2 (162 aa) |
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0.531 | ||||||||||
 | TMCC1 | transmembrane and coiled-coil domain family 1 (653 aa) |
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0.522 | ||||||||||
 | MARC1 | mitochondrial amidoxime reducing component 1 (337 aa) |
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0.496 | ||||||||||
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man
Other names: H. sapiens, Homo, Homo sapiens, human, man
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