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STRINGSTRING
OSBPL1A OSBPL1A CABLES2 CABLES2 UBC UBC CABLES1 CABLES1 OSBPL2 OSBPL2 ABHD3 ABHD3 YIPF5 YIPF5 YIPF2 YIPF2
"ABHD3" - abhydrolase domain containing 3 in Homo sapiens
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Size
small protein node
small nodes:
protein of unknown 3D structure
large protein node
large nodes:
some 3D structure is known or predicted
Node Color
colored protein node
colored nodes:
query proteins and first shell of interactors
non-colored protein node
white nodes:
second shell of interactors
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
database edge
from curated databases
experiment edge
experimentally determined
Predicted Interactions
neighborhood edge
gene neighborhood
fusion edge
gene fusions
cooccurrence edge
gene co-occurrence
Others
textmining edge
textmining
coexpression edge
co-expression
homology edge
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ABHD3abhydrolase domain containing 3 (409 aa)    
Predicted Functional Partners:
UBC
ubiquitin C (685 aa)
        score_image       0.746
OSBPL1A
oxysterol binding protein-like 1A; Binds phospholipids; exhibits strong binding to phosphatidic acid and weak binding to phosphatidylinositol 3- phosphate (By similarity). Stabilizes GTP-bound RAB7A on late endosomes/lysosomes and alters functional properties of late endocytic compartments via its interaction with RAB7A (950 aa)
            score_image   0.622
CABLES1
Cdk5 and Abl enzyme substrate 1; Cyclin-dependent kinase binding protein. Enhances cyclin-dependent kinase tyrosine phosphorylation by nonreceptor tyrosine kinases, such as that of CDK5 by activated ABL1, which leads to increased CDK5 activity and is critical for neuronal development, and that of CDK2 by WEE1, which leads to decreased CDK2 activity and growth inhibition. Positively affects neuronal outgrowth. Plays a role as a regulator for p53/p73-induced cell death (By similarity) (633 aa)
            score_image   0.598
OSBPL2
oxysterol binding protein-like 2; Binds phospholipids; exhibits strong binding to phosphatidic acid and weak binding to phosphatidylinositol 3- phosphate (480 aa)
            score_image   0.587
CABLES2
Cdk5 and Abl enzyme substrate 2; Unknown. Probably involved in G1-S cell cycle transition (478 aa)
            score_image   0.566
YIPF2
Yip1 domain family, member 2 (316 aa)
        score_image       0.439
YIPF5
Yip1 domain family, member 5; Plays a role in transport between endoplasmic reticulum and Golgi (257 aa)
        score_image   score_image   0.413
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man
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