node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ABHD3 | CABLES1 | ENSP00000289119 | ENSP00000256925 | abhydrolase domain containing 3 | Cdk5 and Abl enzyme substrate 1; Cyclin-dependent kinase binding protein. Enhances cyclin-dependent kinase tyrosine phosphorylation by nonreceptor tyrosine kinases, such as that of CDK5 by activated ABL1, which leads to increased CDK5 activity and is critical for neuronal development, and that of CDK2 by WEE1, which leads to decreased CDK2 activity and growth inhibition. Positively affects neuronal outgrowth. Plays a role as a regulator for p53/p73-induced cell death (By similarity) | 0.598 |
ABHD3 | CABLES2 | ENSP00000289119 | ENSP00000279101 | abhydrolase domain containing 3 | Cdk5 and Abl enzyme substrate 2; Unknown. Probably involved in G1-S cell cycle transition | 0.566 |
ABHD3 | OSBPL1A | ENSP00000289119 | ENSP00000320291 | abhydrolase domain containing 3 | oxysterol binding protein-like 1A; Binds phospholipids; exhibits strong binding to phosphatidic acid and weak binding to phosphatidylinositol 3- phosphate (By similarity). Stabilizes GTP-bound RAB7A on late endosomes/lysosomes and alters functional properties of late endocytic compartments via its interaction with RAB7A | 0.622 |
ABHD3 | OSBPL2 | ENSP00000289119 | ENSP00000316649 | abhydrolase domain containing 3 | oxysterol binding protein-like 2; Binds phospholipids; exhibits strong binding to phosphatidic acid and weak binding to phosphatidylinositol 3- phosphate | 0.587 |
ABHD3 | UBC | ENSP00000289119 | ENSP00000344818 | abhydrolase domain containing 3 | ubiquitin C | 0.746 |
ABHD3 | YIPF2 | ENSP00000289119 | ENSP00000253031 | abhydrolase domain containing 3 | Yip1 domain family, member 2 | 0.439 |
ABHD3 | YIPF5 | ENSP00000289119 | ENSP00000274496 | abhydrolase domain containing 3 | Yip1 domain family, member 5; Plays a role in transport between endoplasmic reticulum and Golgi | 0.413 |
CABLES1 | ABHD3 | ENSP00000256925 | ENSP00000289119 | Cdk5 and Abl enzyme substrate 1; Cyclin-dependent kinase binding protein. Enhances cyclin-dependent kinase tyrosine phosphorylation by nonreceptor tyrosine kinases, such as that of CDK5 by activated ABL1, which leads to increased CDK5 activity and is critical for neuronal development, and that of CDK2 by WEE1, which leads to decreased CDK2 activity and growth inhibition. Positively affects neuronal outgrowth. Plays a role as a regulator for p53/p73-induced cell death (By similarity) | abhydrolase domain containing 3 | 0.598 |
CABLES1 | OSBPL1A | ENSP00000256925 | ENSP00000320291 | Cdk5 and Abl enzyme substrate 1; Cyclin-dependent kinase binding protein. Enhances cyclin-dependent kinase tyrosine phosphorylation by nonreceptor tyrosine kinases, such as that of CDK5 by activated ABL1, which leads to increased CDK5 activity and is critical for neuronal development, and that of CDK2 by WEE1, which leads to decreased CDK2 activity and growth inhibition. Positively affects neuronal outgrowth. Plays a role as a regulator for p53/p73-induced cell death (By similarity) | oxysterol binding protein-like 1A; Binds phospholipids; exhibits strong binding to phosphatidic acid and weak binding to phosphatidylinositol 3- phosphate (By similarity). Stabilizes GTP-bound RAB7A on late endosomes/lysosomes and alters functional properties of late endocytic compartments via its interaction with RAB7A | 0.507 |
CABLES1 | OSBPL2 | ENSP00000256925 | ENSP00000316649 | Cdk5 and Abl enzyme substrate 1; Cyclin-dependent kinase binding protein. Enhances cyclin-dependent kinase tyrosine phosphorylation by nonreceptor tyrosine kinases, such as that of CDK5 by activated ABL1, which leads to increased CDK5 activity and is critical for neuronal development, and that of CDK2 by WEE1, which leads to decreased CDK2 activity and growth inhibition. Positively affects neuronal outgrowth. Plays a role as a regulator for p53/p73-induced cell death (By similarity) | oxysterol binding protein-like 2; Binds phospholipids; exhibits strong binding to phosphatidic acid and weak binding to phosphatidylinositol 3- phosphate | 0.485 |
CABLES2 | ABHD3 | ENSP00000279101 | ENSP00000289119 | Cdk5 and Abl enzyme substrate 2; Unknown. Probably involved in G1-S cell cycle transition | abhydrolase domain containing 3 | 0.566 |
CABLES2 | OSBPL1A | ENSP00000279101 | ENSP00000320291 | Cdk5 and Abl enzyme substrate 2; Unknown. Probably involved in G1-S cell cycle transition | oxysterol binding protein-like 1A; Binds phospholipids; exhibits strong binding to phosphatidic acid and weak binding to phosphatidylinositol 3- phosphate (By similarity). Stabilizes GTP-bound RAB7A on late endosomes/lysosomes and alters functional properties of late endocytic compartments via its interaction with RAB7A | 0.485 |
CABLES2 | OSBPL2 | ENSP00000279101 | ENSP00000316649 | Cdk5 and Abl enzyme substrate 2; Unknown. Probably involved in G1-S cell cycle transition | oxysterol binding protein-like 2; Binds phospholipids; exhibits strong binding to phosphatidic acid and weak binding to phosphatidylinositol 3- phosphate | 0.485 |
OSBPL1A | ABHD3 | ENSP00000320291 | ENSP00000289119 | oxysterol binding protein-like 1A; Binds phospholipids; exhibits strong binding to phosphatidic acid and weak binding to phosphatidylinositol 3- phosphate (By similarity). Stabilizes GTP-bound RAB7A on late endosomes/lysosomes and alters functional properties of late endocytic compartments via its interaction with RAB7A | abhydrolase domain containing 3 | 0.622 |
OSBPL1A | CABLES1 | ENSP00000320291 | ENSP00000256925 | oxysterol binding protein-like 1A; Binds phospholipids; exhibits strong binding to phosphatidic acid and weak binding to phosphatidylinositol 3- phosphate (By similarity). Stabilizes GTP-bound RAB7A on late endosomes/lysosomes and alters functional properties of late endocytic compartments via its interaction with RAB7A | Cdk5 and Abl enzyme substrate 1; Cyclin-dependent kinase binding protein. Enhances cyclin-dependent kinase tyrosine phosphorylation by nonreceptor tyrosine kinases, such as that of CDK5 by activated ABL1, which leads to increased CDK5 activity and is critical for neuronal development, and that of CDK2 by WEE1, which leads to decreased CDK2 activity and growth inhibition. Positively affects neuronal outgrowth. Plays a role as a regulator for p53/p73-induced cell death (By similarity) | 0.507 |
OSBPL1A | CABLES2 | ENSP00000320291 | ENSP00000279101 | oxysterol binding protein-like 1A; Binds phospholipids; exhibits strong binding to phosphatidic acid and weak binding to phosphatidylinositol 3- phosphate (By similarity). Stabilizes GTP-bound RAB7A on late endosomes/lysosomes and alters functional properties of late endocytic compartments via its interaction with RAB7A | Cdk5 and Abl enzyme substrate 2; Unknown. Probably involved in G1-S cell cycle transition | 0.485 |
OSBPL1A | UBC | ENSP00000320291 | ENSP00000344818 | oxysterol binding protein-like 1A; Binds phospholipids; exhibits strong binding to phosphatidic acid and weak binding to phosphatidylinositol 3- phosphate (By similarity). Stabilizes GTP-bound RAB7A on late endosomes/lysosomes and alters functional properties of late endocytic compartments via its interaction with RAB7A | ubiquitin C | 0.620 |
OSBPL2 | ABHD3 | ENSP00000316649 | ENSP00000289119 | oxysterol binding protein-like 2; Binds phospholipids; exhibits strong binding to phosphatidic acid and weak binding to phosphatidylinositol 3- phosphate | abhydrolase domain containing 3 | 0.587 |
OSBPL2 | CABLES1 | ENSP00000316649 | ENSP00000256925 | oxysterol binding protein-like 2; Binds phospholipids; exhibits strong binding to phosphatidic acid and weak binding to phosphatidylinositol 3- phosphate | Cdk5 and Abl enzyme substrate 1; Cyclin-dependent kinase binding protein. Enhances cyclin-dependent kinase tyrosine phosphorylation by nonreceptor tyrosine kinases, such as that of CDK5 by activated ABL1, which leads to increased CDK5 activity and is critical for neuronal development, and that of CDK2 by WEE1, which leads to decreased CDK2 activity and growth inhibition. Positively affects neuronal outgrowth. Plays a role as a regulator for p53/p73-induced cell death (By similarity) | 0.485 |
OSBPL2 | CABLES2 | ENSP00000316649 | ENSP00000279101 | oxysterol binding protein-like 2; Binds phospholipids; exhibits strong binding to phosphatidic acid and weak binding to phosphatidylinositol 3- phosphate | Cdk5 and Abl enzyme substrate 2; Unknown. Probably involved in G1-S cell cycle transition | 0.485 |