FAM46B protein (Homo sapiens) - STRING network view

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Size

small nodes:
protein of unknown 3D structure

large nodes:
some 3D structure is known or predicted

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

FAM46B

family with sequence similarity 46, member B (425 aa)

Predicted Functional Partners:

SOX5

0.590

TAMM41

0.538

C2orf54

0.510

KIAA0232

0.503

MB21D2

0.485

SMCR7L

0.480

VAMP5

0.475

GALM

0.474

GOT1L1

0.459

STRBP

0.452

Your Current Organism:

Homo sapiens

NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but resolution at 400 dpi

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as simple tabular text output:

download

TSV: tab separated values - can be opened in Excel

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and annotated functions of the network proteins

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
C2orf54	FAM46B	ENSP00000373586	ENSP00000289166	chromosome 2 open reading frame 54	family with sequence similarity 46, member B	0.510
C2orf54	MB21D2	ENSP00000373586	ENSP00000376246	chromosome 2 open reading frame 54	Mab-21 domain containing 2	0.537
C2orf54	SMCR7L	ENSP00000373586	ENSP00000327124	chromosome 2 open reading frame 54	Smith-Magenis syndrome chromosome region, candidate 7-like; Mitochondrial outer membrane protein which regulates mitochondrial morphology. Mitochondrial morphology is controlled by two opposites processes- fusion and fission. Seems to have a key role in inhibiting DNM1L-induced mitochondrial fission	0.472
C2orf54	TAMM41	ENSP00000373586	ENSP00000273037	chromosome 2 open reading frame 54	TAM41, mitochondrial translocator assembly and maintenance protein, homolog (S. cerevisiae); May be involved in the translocation of transit peptide- containing proteins across the mitochondrial inner membrane (By similarity)	0.515
FAM46B	C2orf54	ENSP00000289166	ENSP00000373586	family with sequence similarity 46, member B	chromosome 2 open reading frame 54	0.510
FAM46B	GALM	ENSP00000289166	ENSP00000272252	family with sequence similarity 46, member B	galactose mutarotase (aldose 1-epimerase); Mutarotase converts alpha-aldose to the beta-anomer. It is active on D-glucose, L-arabinose, D-xylose, D-galactose, maltose and lactose (By similarity)	0.474
FAM46B	GOT1L1	ENSP00000289166	ENSP00000303077	family with sequence similarity 46, member B	glutamic-oxaloacetic transaminase 1-like 1	0.459
FAM46B	KIAA0232	ENSP00000289166	ENSP00000303928	family with sequence similarity 46, member B	KIAA0232	0.503
FAM46B	MB21D2	ENSP00000289166	ENSP00000376246	family with sequence similarity 46, member B	Mab-21 domain containing 2	0.485
FAM46B	SMCR7L	ENSP00000289166	ENSP00000327124	family with sequence similarity 46, member B	Smith-Magenis syndrome chromosome region, candidate 7-like; Mitochondrial outer membrane protein which regulates mitochondrial morphology. Mitochondrial morphology is controlled by two opposites processes- fusion and fission. Seems to have a key role in inhibiting DNM1L-induced mitochondrial fission	0.480
FAM46B	SOX5	ENSP00000289166	ENSP00000398273	family with sequence similarity 46, member B	SRY (sex determining region Y)-box 5	0.590
FAM46B	STRBP	ENSP00000289166	ENSP00000321347	family with sequence similarity 46, member B	spermatid perinuclear RNA binding protein; Involved in spermatogenesis and sperm function. Plays a role in regulation of cell growth. Binds to double-stranded DNA and RNA. Binds most efficiently to poly(I-C) RNA than to poly(dI-dC) DNA. Binds also to single-stranded poly(G) RNA. Binds non-specifically to the mRNA PRM1 3’-UTR and adenovirus VA RNA (By similarity)	0.452
FAM46B	TAMM41	ENSP00000289166	ENSP00000273037	family with sequence similarity 46, member B	TAM41, mitochondrial translocator assembly and maintenance protein, homolog (S. cerevisiae); May be involved in the translocation of transit peptide- containing proteins across the mitochondrial inner membrane (By similarity)	0.538
FAM46B	VAMP5	ENSP00000289166	ENSP00000305647	family with sequence similarity 46, member B	vesicle-associated membrane protein 5; May participate in trafficking events that are associated with myogenesis, such as myoblast fusion and/or GLUT4 trafficking	0.475
GALM	FAM46B	ENSP00000272252	ENSP00000289166	galactose mutarotase (aldose 1-epimerase); Mutarotase converts alpha-aldose to the beta-anomer. It is active on D-glucose, L-arabinose, D-xylose, D-galactose, maltose and lactose (By similarity)	family with sequence similarity 46, member B	0.474
GOT1L1	FAM46B	ENSP00000303077	ENSP00000289166	glutamic-oxaloacetic transaminase 1-like 1	family with sequence similarity 46, member B	0.459
KIAA0232	FAM46B	ENSP00000303928	ENSP00000289166	KIAA0232	family with sequence similarity 46, member B	0.503
MB21D2	C2orf54	ENSP00000376246	ENSP00000373586	Mab-21 domain containing 2	chromosome 2 open reading frame 54	0.537
MB21D2	FAM46B	ENSP00000376246	ENSP00000289166	Mab-21 domain containing 2	family with sequence similarity 46, member B	0.485
MB21D2	SMCR7L	ENSP00000376246	ENSP00000327124	Mab-21 domain containing 2	Smith-Magenis syndrome chromosome region, candidate 7-like; Mitochondrial outer membrane protein which regulates mitochondrial morphology. Mitochondrial morphology is controlled by two opposites processes- fusion and fission. Seems to have a key role in inhibiting DNM1L-induced mitochondrial fission	0.579

page 1 of 2

Experiments

Cooccurrence

Textmining

Neighborhood

Databases

Fusion

Coexpression

© STRING Consortium 2017

Credits

Access

Info

About