ACTR1B protein (Homo sapiens) - STRING network view

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ACTR1B

ARP1 actin-related protein 1 homolog B, centractin beta (yeast); Component of a multi-subunit complex involved in microtubule based vesicle motility. It is associated with the centrosome (376 aa)

Predicted Functional Partners:

DCTN2

0.999

DCTN3

0.999

ACTR1A

0.999

DCTN1

0.998

DCTN5

0.972

DCTN4

0.970

DYNC2H1

0.959

DYNC1H1

0.959

DCTN6

0.953

DYNC1I2

0.943

Your Current Organism:

Homo sapiens

NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ACTR1A	ACTR1B	ENSP00000358921	ENSP00000289228	ARP1 actin-related protein 1 homolog A, centractin alpha (yeast); Component of a multi-subunit complex involved in microtubule based vesicle motility. It is associated with the centrosome	ARP1 actin-related protein 1 homolog B, centractin beta (yeast); Component of a multi-subunit complex involved in microtubule based vesicle motility. It is associated with the centrosome	0.999
ACTR1A	DCTN1	ENSP00000358921	ENSP00000354791	ARP1 actin-related protein 1 homolog A, centractin alpha (yeast); Component of a multi-subunit complex involved in microtubule based vesicle motility. It is associated with the centrosome	dynactin 1	0.999
ACTR1A	DCTN2	ENSP00000358921	ENSP00000408910	ARP1 actin-related protein 1 homolog A, centractin alpha (yeast); Component of a multi-subunit complex involved in microtubule based vesicle motility. It is associated with the centrosome	dynactin 2 (p50); Modulates cytoplasmic dynein binding to an organelle, and plays a role in prometaphase chromosome alignment and spindle organization during mitosis. Involved in anchoring microtubules to centrosomes. May play a role in synapse formation during brain development	0.999
ACTR1A	DCTN3	ENSP00000358921	ENSP00000259632	ARP1 actin-related protein 1 homolog A, centractin alpha (yeast); Component of a multi-subunit complex involved in microtubule based vesicle motility. It is associated with the centrosome	dynactin 3 (p22); Together with dynein may be involved in spindle assembly and cytokinesis	0.951
ACTR1A	DCTN4	ENSP00000358921	ENSP00000414906	ARP1 actin-related protein 1 homolog A, centractin alpha (yeast); Component of a multi-subunit complex involved in microtubule based vesicle motility. It is associated with the centrosome	dynactin 4 (p62); Could have a dual role in dynein targeting and in ACTR1A/Arp1 subunit of dynactin pointed-end capping. Could be involved in ACTR1A pointed-end binding and in additional roles in linking dynein and dynactin to the cortical cytoskeleton	0.994
ACTR1A	DCTN5	ENSP00000358921	ENSP00000300087	ARP1 actin-related protein 1 homolog A, centractin alpha (yeast); Component of a multi-subunit complex involved in microtubule based vesicle motility. It is associated with the centrosome	dynactin 5 (p25)	0.973
ACTR1A	DCTN6	ENSP00000358921	ENSP00000221114	ARP1 actin-related protein 1 homolog A, centractin alpha (yeast); Component of a multi-subunit complex involved in microtubule based vesicle motility. It is associated with the centrosome	dynactin 6	0.953
ACTR1A	DYNC1H1	ENSP00000358921	ENSP00000348965	ARP1 actin-related protein 1 homolog A, centractin alpha (yeast); Component of a multi-subunit complex involved in microtubule based vesicle motility. It is associated with the centrosome	dynein, cytoplasmic 1, heavy chain 1; Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. Dynein has ATPase activity; the force-producing power stroke is thought to occur on release of ADP	0.959
ACTR1A	DYNC1I2	ENSP00000358921	ENSP00000380308	ARP1 actin-related protein 1 homolog A, centractin alpha (yeast); Component of a multi-subunit complex involved in microtubule based vesicle motility. It is associated with the centrosome	dynein, cytoplasmic 1, intermediate chain 2	0.943
ACTR1A	DYNC2H1	ENSP00000358921	ENSP00000381167	ARP1 actin-related protein 1 homolog A, centractin alpha (yeast); Component of a multi-subunit complex involved in microtubule based vesicle motility. It is associated with the centrosome	dynein, cytoplasmic 2, heavy chain 1	0.959
ACTR1B	ACTR1A	ENSP00000289228	ENSP00000358921	ARP1 actin-related protein 1 homolog B, centractin beta (yeast); Component of a multi-subunit complex involved in microtubule based vesicle motility. It is associated with the centrosome	ARP1 actin-related protein 1 homolog A, centractin alpha (yeast); Component of a multi-subunit complex involved in microtubule based vesicle motility. It is associated with the centrosome	0.999
ACTR1B	DCTN1	ENSP00000289228	ENSP00000354791	ARP1 actin-related protein 1 homolog B, centractin beta (yeast); Component of a multi-subunit complex involved in microtubule based vesicle motility. It is associated with the centrosome	dynactin 1	0.998
ACTR1B	DCTN2	ENSP00000289228	ENSP00000408910	ARP1 actin-related protein 1 homolog B, centractin beta (yeast); Component of a multi-subunit complex involved in microtubule based vesicle motility. It is associated with the centrosome	dynactin 2 (p50); Modulates cytoplasmic dynein binding to an organelle, and plays a role in prometaphase chromosome alignment and spindle organization during mitosis. Involved in anchoring microtubules to centrosomes. May play a role in synapse formation during brain development	0.999
ACTR1B	DCTN3	ENSP00000289228	ENSP00000259632	ARP1 actin-related protein 1 homolog B, centractin beta (yeast); Component of a multi-subunit complex involved in microtubule based vesicle motility. It is associated with the centrosome	dynactin 3 (p22); Together with dynein may be involved in spindle assembly and cytokinesis	0.999
ACTR1B	DCTN4	ENSP00000289228	ENSP00000414906	ARP1 actin-related protein 1 homolog B, centractin beta (yeast); Component of a multi-subunit complex involved in microtubule based vesicle motility. It is associated with the centrosome	dynactin 4 (p62); Could have a dual role in dynein targeting and in ACTR1A/Arp1 subunit of dynactin pointed-end capping. Could be involved in ACTR1A pointed-end binding and in additional roles in linking dynein and dynactin to the cortical cytoskeleton	0.970
ACTR1B	DCTN5	ENSP00000289228	ENSP00000300087	ARP1 actin-related protein 1 homolog B, centractin beta (yeast); Component of a multi-subunit complex involved in microtubule based vesicle motility. It is associated with the centrosome	dynactin 5 (p25)	0.972
ACTR1B	DCTN6	ENSP00000289228	ENSP00000221114	ARP1 actin-related protein 1 homolog B, centractin beta (yeast); Component of a multi-subunit complex involved in microtubule based vesicle motility. It is associated with the centrosome	dynactin 6	0.953
ACTR1B	DYNC1H1	ENSP00000289228	ENSP00000348965	ARP1 actin-related protein 1 homolog B, centractin beta (yeast); Component of a multi-subunit complex involved in microtubule based vesicle motility. It is associated with the centrosome	dynein, cytoplasmic 1, heavy chain 1; Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. Dynein has ATPase activity; the force-producing power stroke is thought to occur on release of ADP	0.959
ACTR1B	DYNC1I2	ENSP00000289228	ENSP00000380308	ARP1 actin-related protein 1 homolog B, centractin beta (yeast); Component of a multi-subunit complex involved in microtubule based vesicle motility. It is associated with the centrosome	dynein, cytoplasmic 1, intermediate chain 2	0.943
ACTR1B	DYNC2H1	ENSP00000289228	ENSP00000381167	ARP1 actin-related protein 1 homolog B, centractin beta (yeast); Component of a multi-subunit complex involved in microtubule based vesicle motility. It is associated with the centrosome	dynein, cytoplasmic 2, heavy chain 1	0.959

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