TMSB15A protein (Homo sapiens) - STRING network view

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TMSB15A

thymosin beta 15a; Plays an important role in the organization of the cytoskeleton. Binds to and sequesters actin monomers (G actin) and therefore inhibits actin polymerization (By similarity) (45 aa)

Predicted Functional Partners:

C1orf106

0.567

PFN4

0.466

PFN2

0.466

PFN1

0.466

TMEM158

0.414

Your Current Organism:

Homo sapiens

NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
C1orf106	TMSB15A	ENSP00000356311	ENSP00000289373	chromosome 1 open reading frame 106	thymosin beta 15a; Plays an important role in the organization of the cytoskeleton. Binds to and sequesters actin monomers (G actin) and therefore inhibits actin polymerization (By similarity)	0.567
PFN1	PFN4	ENSP00000225655	ENSP00000322170	profilin 1; Binds to actin and affects the structure of the cytoskeleton. At high concentrations, profilin prevents the polymerization of actin, whereas it enhances it at low concentrations. By binding to PIP2, it inhibits the formation of IP3 and DG. Inhibits androgen receptor (AR) and HTT aggregation and binding of G-actin is essential for its inhibition of AR	profilin family, member 4; Binds to actin and affects the structure of the cytoskeleton (By similarity)	0.566
PFN1	TMSB15A	ENSP00000225655	ENSP00000289373	profilin 1; Binds to actin and affects the structure of the cytoskeleton. At high concentrations, profilin prevents the polymerization of actin, whereas it enhances it at low concentrations. By binding to PIP2, it inhibits the formation of IP3 and DG. Inhibits androgen receptor (AR) and HTT aggregation and binding of G-actin is essential for its inhibition of AR	thymosin beta 15a; Plays an important role in the organization of the cytoskeleton. Binds to and sequesters actin monomers (G actin) and therefore inhibits actin polymerization (By similarity)	0.466
PFN2	PFN4	ENSP00000239940	ENSP00000322170	profilin 2; Binds to actin and affects the structure of the cytoskeleton. At high concentrations, profilin prevents the polymerization of actin, whereas it enhances it at low concentrations. By binding to PIP2, it inhibits the formation of IP3 and DG	profilin family, member 4; Binds to actin and affects the structure of the cytoskeleton (By similarity)	0.740
PFN2	TMSB15A	ENSP00000239940	ENSP00000289373	profilin 2; Binds to actin and affects the structure of the cytoskeleton. At high concentrations, profilin prevents the polymerization of actin, whereas it enhances it at low concentrations. By binding to PIP2, it inhibits the formation of IP3 and DG	thymosin beta 15a; Plays an important role in the organization of the cytoskeleton. Binds to and sequesters actin monomers (G actin) and therefore inhibits actin polymerization (By similarity)	0.466
PFN4	PFN1	ENSP00000322170	ENSP00000225655	profilin family, member 4; Binds to actin and affects the structure of the cytoskeleton (By similarity)	profilin 1; Binds to actin and affects the structure of the cytoskeleton. At high concentrations, profilin prevents the polymerization of actin, whereas it enhances it at low concentrations. By binding to PIP2, it inhibits the formation of IP3 and DG. Inhibits androgen receptor (AR) and HTT aggregation and binding of G-actin is essential for its inhibition of AR	0.566
PFN4	PFN2	ENSP00000322170	ENSP00000239940	profilin family, member 4; Binds to actin and affects the structure of the cytoskeleton (By similarity)	profilin 2; Binds to actin and affects the structure of the cytoskeleton. At high concentrations, profilin prevents the polymerization of actin, whereas it enhances it at low concentrations. By binding to PIP2, it inhibits the formation of IP3 and DG	0.740
PFN4	TMSB15A	ENSP00000322170	ENSP00000289373	profilin family, member 4; Binds to actin and affects the structure of the cytoskeleton (By similarity)	thymosin beta 15a; Plays an important role in the organization of the cytoskeleton. Binds to and sequesters actin monomers (G actin) and therefore inhibits actin polymerization (By similarity)	0.466
TMEM158	TMSB15A	ENSP00000422431	ENSP00000289373	transmembrane protein 158 (gene/pseudogene); Receptor for brain injury-derived neurotrophic peptide (BINP), a synthetic 13-mer peptide (By similarity)	thymosin beta 15a; Plays an important role in the organization of the cytoskeleton. Binds to and sequesters actin monomers (G actin) and therefore inhibits actin polymerization (By similarity)	0.414
TMSB15A	C1orf106	ENSP00000289373	ENSP00000356311	thymosin beta 15a; Plays an important role in the organization of the cytoskeleton. Binds to and sequesters actin monomers (G actin) and therefore inhibits actin polymerization (By similarity)	chromosome 1 open reading frame 106	0.567
TMSB15A	PFN1	ENSP00000289373	ENSP00000225655	thymosin beta 15a; Plays an important role in the organization of the cytoskeleton. Binds to and sequesters actin monomers (G actin) and therefore inhibits actin polymerization (By similarity)	profilin 1; Binds to actin and affects the structure of the cytoskeleton. At high concentrations, profilin prevents the polymerization of actin, whereas it enhances it at low concentrations. By binding to PIP2, it inhibits the formation of IP3 and DG. Inhibits androgen receptor (AR) and HTT aggregation and binding of G-actin is essential for its inhibition of AR	0.466
TMSB15A	PFN2	ENSP00000289373	ENSP00000239940	thymosin beta 15a; Plays an important role in the organization of the cytoskeleton. Binds to and sequesters actin monomers (G actin) and therefore inhibits actin polymerization (By similarity)	profilin 2; Binds to actin and affects the structure of the cytoskeleton. At high concentrations, profilin prevents the polymerization of actin, whereas it enhances it at low concentrations. By binding to PIP2, it inhibits the formation of IP3 and DG	0.466
TMSB15A	PFN4	ENSP00000289373	ENSP00000322170	thymosin beta 15a; Plays an important role in the organization of the cytoskeleton. Binds to and sequesters actin monomers (G actin) and therefore inhibits actin polymerization (By similarity)	profilin family, member 4; Binds to actin and affects the structure of the cytoskeleton (By similarity)	0.466
TMSB15A	TMEM158	ENSP00000289373	ENSP00000422431	thymosin beta 15a; Plays an important role in the organization of the cytoskeleton. Binds to and sequesters actin monomers (G actin) and therefore inhibits actin polymerization (By similarity)	transmembrane protein 158 (gene/pseudogene); Receptor for brain injury-derived neurotrophic peptide (BINP), a synthetic 13-mer peptide (By similarity)	0.414

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