CD1A protein (Homo sapiens) - STRING network view

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CD1A

CD1a molecule; Antigen-presenting protein that binds self and non-self lipid and glycolipid antigens and presents them to T-cell receptors on natural killer T-cells (327 aa)

Predicted Functional Partners:

B2M

0.860

VWA5A

0.644

KIRREL

0.515

CD207

0.472

CD83

0.461

C22orf31

0.414

Your Current Organism:

Homo sapiens

NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
B2M	CD1A	ENSP00000452780	ENSP00000289429	beta-2-microglobulin; Component of the class I major histocompatibility complex (MHC). Involved in the presentation of peptide antigens to the immune system (By similarity)	CD1a molecule; Antigen-presenting protein that binds self and non-self lipid and glycolipid antigens and presents them to T-cell receptors on natural killer T-cells	0.860
C22orf31	CD1A	ENSP00000216071	ENSP00000289429	chromosome 22 open reading frame 31	CD1a molecule; Antigen-presenting protein that binds self and non-self lipid and glycolipid antigens and presents them to T-cell receptors on natural killer T-cells	0.414
CD1A	B2M	ENSP00000289429	ENSP00000452780	CD1a molecule; Antigen-presenting protein that binds self and non-self lipid and glycolipid antigens and presents them to T-cell receptors on natural killer T-cells	beta-2-microglobulin; Component of the class I major histocompatibility complex (MHC). Involved in the presentation of peptide antigens to the immune system (By similarity)	0.860
CD1A	C22orf31	ENSP00000289429	ENSP00000216071	CD1a molecule; Antigen-presenting protein that binds self and non-self lipid and glycolipid antigens and presents them to T-cell receptors on natural killer T-cells	chromosome 22 open reading frame 31	0.414
CD1A	CD207	ENSP00000289429	ENSP00000386378	CD1a molecule; Antigen-presenting protein that binds self and non-self lipid and glycolipid antigens and presents them to T-cell receptors on natural killer T-cells	CD207 molecule, langerin; Calcium-dependent lectin displaying mannose-binding specificity. Induces the formation of Birbeck granules (BGs); is a potent regulator of membrane superimposition and zippering. Binds to sulfated as well as mannosylated glycans, keratan sulfate (KS) and beta-glucans. Facilitates uptake of antigens and is involved in the routing and/or processing of antigen for presentation to T cells. Major receptor on primary Langerhans cells for Candida species, Saccharomyces species, and Malassezia furfur. Protects against human immunodeficiency virus-1 (HIV-1) infection. [...]	0.472
CD1A	CD83	ENSP00000289429	ENSP00000368450	CD1a molecule; Antigen-presenting protein that binds self and non-self lipid and glycolipid antigens and presents them to T-cell receptors on natural killer T-cells	CD83 molecule; May play a significant role in antigen presentation or the cellular interactions that follow lymphocyte activation	0.461
CD1A	KIRREL	ENSP00000289429	ENSP00000352138	CD1a molecule; Antigen-presenting protein that binds self and non-self lipid and glycolipid antigens and presents them to T-cell receptors on natural killer T-cells	kin of IRRE like (Drosophila); Plays a significant role in the normal development and function of the glomerular permeability. Signaling protein that needs the presence of TEC kinases to fully trans-activate the transcription factor AP-1 (By similarity)	0.515
CD1A	VWA5A	ENSP00000289429	ENSP00000376504	CD1a molecule; Antigen-presenting protein that binds self and non-self lipid and glycolipid antigens and presents them to T-cell receptors on natural killer T-cells	von Willebrand factor A domain containing 5A; May play a role in tumorigenesis as a tumor suppressor. Altered expression of this protein and disruption of the molecular pathway it is involved in, may contribute directly to or modify tumorigenesis	0.644
CD207	CD1A	ENSP00000386378	ENSP00000289429	CD207 molecule, langerin; Calcium-dependent lectin displaying mannose-binding specificity. Induces the formation of Birbeck granules (BGs); is a potent regulator of membrane superimposition and zippering. Binds to sulfated as well as mannosylated glycans, keratan sulfate (KS) and beta-glucans. Facilitates uptake of antigens and is involved in the routing and/or processing of antigen for presentation to T cells. Major receptor on primary Langerhans cells for Candida species, Saccharomyces species, and Malassezia furfur. Protects against human immunodeficiency virus-1 (HIV-1) infection. [...]	CD1a molecule; Antigen-presenting protein that binds self and non-self lipid and glycolipid antigens and presents them to T-cell receptors on natural killer T-cells	0.472
CD207	CD83	ENSP00000386378	ENSP00000368450	CD207 molecule, langerin; Calcium-dependent lectin displaying mannose-binding specificity. Induces the formation of Birbeck granules (BGs); is a potent regulator of membrane superimposition and zippering. Binds to sulfated as well as mannosylated glycans, keratan sulfate (KS) and beta-glucans. Facilitates uptake of antigens and is involved in the routing and/or processing of antigen for presentation to T cells. Major receptor on primary Langerhans cells for Candida species, Saccharomyces species, and Malassezia furfur. Protects against human immunodeficiency virus-1 (HIV-1) infection. [...]	CD83 molecule; May play a significant role in antigen presentation or the cellular interactions that follow lymphocyte activation	0.723
CD83	CD1A	ENSP00000368450	ENSP00000289429	CD83 molecule; May play a significant role in antigen presentation or the cellular interactions that follow lymphocyte activation	CD1a molecule; Antigen-presenting protein that binds self and non-self lipid and glycolipid antigens and presents them to T-cell receptors on natural killer T-cells	0.461
CD83	CD207	ENSP00000368450	ENSP00000386378	CD83 molecule; May play a significant role in antigen presentation or the cellular interactions that follow lymphocyte activation	CD207 molecule, langerin; Calcium-dependent lectin displaying mannose-binding specificity. Induces the formation of Birbeck granules (BGs); is a potent regulator of membrane superimposition and zippering. Binds to sulfated as well as mannosylated glycans, keratan sulfate (KS) and beta-glucans. Facilitates uptake of antigens and is involved in the routing and/or processing of antigen for presentation to T cells. Major receptor on primary Langerhans cells for Candida species, Saccharomyces species, and Malassezia furfur. Protects against human immunodeficiency virus-1 (HIV-1) infection. [...]	0.723
KIRREL	CD1A	ENSP00000352138	ENSP00000289429	kin of IRRE like (Drosophila); Plays a significant role in the normal development and function of the glomerular permeability. Signaling protein that needs the presence of TEC kinases to fully trans-activate the transcription factor AP-1 (By similarity)	CD1a molecule; Antigen-presenting protein that binds self and non-self lipid and glycolipid antigens and presents them to T-cell receptors on natural killer T-cells	0.515
VWA5A	CD1A	ENSP00000376504	ENSP00000289429	von Willebrand factor A domain containing 5A; May play a role in tumorigenesis as a tumor suppressor. Altered expression of this protein and disruption of the molecular pathway it is involved in, may contribute directly to or modify tumorigenesis	CD1a molecule; Antigen-presenting protein that binds self and non-self lipid and glycolipid antigens and presents them to T-cell receptors on natural killer T-cells	0.644

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