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MRPL1 MRPL1 MRPL15 MRPL15 MRPL23 MRPL23 MRPL11 MRPL11 MRPL3 MRPL3 MRPL12 MRPL12 MRPL13 MRPL13 TP53I3 TP53I3 MRPL10 MRPL10 ICT1 ICT1 SIRT3 SIRT3
"MRPL10" - mitochondrial ribosomal protein L10 in Homo sapiens
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Size
small protein node
small nodes:
protein of unknown 3D structure
large protein node
large nodes:
some 3D structure is known or predicted
Node Color
colored protein node
colored nodes:
query proteins and first shell of interactors
non-colored protein node
white nodes:
second shell of interactors
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
database edge
from curated databases
experiment edge
experimentally determined
Predicted Interactions
neighborhood edge
gene neighborhood
fusion edge
gene fusions
cooccurrence edge
gene co-occurrence
Others
textmining edge
textmining
coexpression edge
co-expression
homology edge
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MRPL10mitochondrial ribosomal protein L10 (271 aa)    
Predicted Functional Partners:
MRPL12
mitochondrial ribosomal protein L12 (198 aa)
      score_image score_image   score_image   0.974
MRPL11
mitochondrial ribosomal protein L11 (192 aa)
      score_image score_image   score_image   0.939
MRPL13
mitochondrial ribosomal protein L13 (178 aa)
      score_image score_image   score_image   0.936
ICT1
immature colon carcinoma transcript 1; Essential peptidyl-tRNA hydrolase component of the mitochondrial large ribosomal subunit. Acts as a codon-independent translation release factor that has lost all stop codon specificity and directs the termination of translation in mitochondrion, possibly in case of abortive elongation. May be involved in the hydrolysis of peptidyl-tRNAs that have been prematurely terminated and thus in the recycling of stalled mitochondrial ribosomes (206 aa)
      score_image score_image       0.928
MRPL23
mitochondrial ribosomal protein L23 (153 aa)
      score_image score_image       0.916
MRPL3
mitochondrial ribosomal protein L3 (348 aa)
      score_image score_image       0.915
MRPL1
mitochondrial ribosomal protein L1 (325 aa)
      score_image score_image   score_image   0.909
TP53I3
tumor protein p53 inducible protein 3; May be involved in the generation of reactive oxygen species (ROS). Has low NADPH-dependent beta-naphthoquinone reductase activity, with a preference for 1,2-beta-naphthoquinone over 1,4-beta-naphthoquinone. Has low NADPH-dependent diamine reductase activity (in vitro) (332 aa)
        score_image       0.902
MRPL15
mitochondrial ribosomal protein L15 (296 aa)
      score_image score_image   score_image   0.888
SIRT3
sirtuin 3; NAD-dependent protein deacetylase. Activates mitochondrial target proteins, including ACSS1, IDH2 and GDH by deacetylating key lysine residues. Contributes to the regulation of the cellular energy metabolism. Important for regulating tissue-specific ATP levels (399 aa)
            score_image   0.878
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man
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