PGLYRP3 protein (Homo sapiens) - STRING network view

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PGLYRP3

peptidoglycan recognition protein 3; Pattern receptor that binds to murein peptidoglycans (PGN) of Gram-positive bacteria. Has bactericidal activity towards Gram-positive bacteria. May kill Gram-positive bacteria by interfering with peptidoglycan biosynthesis. Binds also to Gram- negative bacteria, and has bacteriostatic activity towards Gram- negative bacteria. Plays a role in innate immunity (341 aa)

Predicted Functional Partners:

PPARG

0.815

LCE3B

0.680

LCE1A

0.680

LCE3C

0.610

WSCD2

0.592

SPG7

0.581

ZC3H7B

0.485

ELOVL6

0.457

IVL

0.440

APEH

0.414

Your Current Organism:

Homo sapiens

NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
APEH	PGLYRP3	ENSP00000296456	ENSP00000290722	N-acylaminoacyl-peptide hydrolase; This enzyme catalyzes the hydrolysis of the N-terminal peptide bond of an N-acetylated peptide to generate an N- acetylated amino acid and a peptide with a free N-terminus. It preferentially cleaves off Ac-Ala, Ac-Met and Ac-Ser	peptidoglycan recognition protein 3; Pattern receptor that binds to murein peptidoglycans (PGN) of Gram-positive bacteria. Has bactericidal activity towards Gram-positive bacteria. May kill Gram-positive bacteria by interfering with peptidoglycan biosynthesis. Binds also to Gram- negative bacteria, and has bacteriostatic activity towards Gram- negative bacteria. Plays a role in innate immunity	0.414
ELOVL6	LCE1A	ENSP00000304736	ENSP00000334869	ELOVL fatty acid elongase 6; Condensing enzyme that catalyzes the synthesis of saturated and monounsaturated fatty acids. Highest activity toward C16-0 acyl-CoAs	late cornified envelope 1A; Precursors of the cornified envelope of the stratum corneum	0.561
ELOVL6	LCE3B	ENSP00000304736	ENSP00000335358	ELOVL fatty acid elongase 6; Condensing enzyme that catalyzes the synthesis of saturated and monounsaturated fatty acids. Highest activity toward C16-0 acyl-CoAs	late cornified envelope 3B; Precursors of the cornified envelope of the stratum corneum	0.745
ELOVL6	LCE3C	ENSP00000304736	ENSP00000334644	ELOVL fatty acid elongase 6; Condensing enzyme that catalyzes the synthesis of saturated and monounsaturated fatty acids. Highest activity toward C16-0 acyl-CoAs	late cornified envelope 3C; Precursors of the cornified envelope of the stratum corneum	0.800
ELOVL6	PGLYRP3	ENSP00000304736	ENSP00000290722	ELOVL fatty acid elongase 6; Condensing enzyme that catalyzes the synthesis of saturated and monounsaturated fatty acids. Highest activity toward C16-0 acyl-CoAs	peptidoglycan recognition protein 3; Pattern receptor that binds to murein peptidoglycans (PGN) of Gram-positive bacteria. Has bactericidal activity towards Gram-positive bacteria. May kill Gram-positive bacteria by interfering with peptidoglycan biosynthesis. Binds also to Gram- negative bacteria, and has bacteriostatic activity towards Gram- negative bacteria. Plays a role in innate immunity	0.457
IVL	LCE1A	ENSP00000357753	ENSP00000334869	involucrin; Part of the insoluble cornified cell envelope (CE) of stratified squamous epithelia (By similarity)	late cornified envelope 1A; Precursors of the cornified envelope of the stratum corneum	0.510
IVL	LCE3B	ENSP00000357753	ENSP00000335358	involucrin; Part of the insoluble cornified cell envelope (CE) of stratified squamous epithelia (By similarity)	late cornified envelope 3B; Precursors of the cornified envelope of the stratum corneum	0.511
IVL	LCE3C	ENSP00000357753	ENSP00000334644	involucrin; Part of the insoluble cornified cell envelope (CE) of stratified squamous epithelia (By similarity)	late cornified envelope 3C; Precursors of the cornified envelope of the stratum corneum	0.455
IVL	PGLYRP3	ENSP00000357753	ENSP00000290722	involucrin; Part of the insoluble cornified cell envelope (CE) of stratified squamous epithelia (By similarity)	peptidoglycan recognition protein 3; Pattern receptor that binds to murein peptidoglycans (PGN) of Gram-positive bacteria. Has bactericidal activity towards Gram-positive bacteria. May kill Gram-positive bacteria by interfering with peptidoglycan biosynthesis. Binds also to Gram- negative bacteria, and has bacteriostatic activity towards Gram- negative bacteria. Plays a role in innate immunity	0.440
IVL	PPARG	ENSP00000357753	ENSP00000287820	involucrin; Part of the insoluble cornified cell envelope (CE) of stratified squamous epithelia (By similarity)	peroxisome proliferator-activated receptor gamma	0.852
LCE1A	ELOVL6	ENSP00000334869	ENSP00000304736	late cornified envelope 1A; Precursors of the cornified envelope of the stratum corneum	ELOVL fatty acid elongase 6; Condensing enzyme that catalyzes the synthesis of saturated and monounsaturated fatty acids. Highest activity toward C16-0 acyl-CoAs	0.561
LCE1A	IVL	ENSP00000334869	ENSP00000357753	late cornified envelope 1A; Precursors of the cornified envelope of the stratum corneum	involucrin; Part of the insoluble cornified cell envelope (CE) of stratified squamous epithelia (By similarity)	0.510
LCE1A	LCE3B	ENSP00000334869	ENSP00000335358	late cornified envelope 1A; Precursors of the cornified envelope of the stratum corneum	late cornified envelope 3B; Precursors of the cornified envelope of the stratum corneum	0.745
LCE1A	LCE3C	ENSP00000334869	ENSP00000334644	late cornified envelope 1A; Precursors of the cornified envelope of the stratum corneum	late cornified envelope 3C; Precursors of the cornified envelope of the stratum corneum	0.681
LCE1A	PGLYRP3	ENSP00000334869	ENSP00000290722	late cornified envelope 1A; Precursors of the cornified envelope of the stratum corneum	peptidoglycan recognition protein 3; Pattern receptor that binds to murein peptidoglycans (PGN) of Gram-positive bacteria. Has bactericidal activity towards Gram-positive bacteria. May kill Gram-positive bacteria by interfering with peptidoglycan biosynthesis. Binds also to Gram- negative bacteria, and has bacteriostatic activity towards Gram- negative bacteria. Plays a role in innate immunity	0.680
LCE3B	ELOVL6	ENSP00000335358	ENSP00000304736	late cornified envelope 3B; Precursors of the cornified envelope of the stratum corneum	ELOVL fatty acid elongase 6; Condensing enzyme that catalyzes the synthesis of saturated and monounsaturated fatty acids. Highest activity toward C16-0 acyl-CoAs	0.745
LCE3B	IVL	ENSP00000335358	ENSP00000357753	late cornified envelope 3B; Precursors of the cornified envelope of the stratum corneum	involucrin; Part of the insoluble cornified cell envelope (CE) of stratified squamous epithelia (By similarity)	0.511
LCE3B	LCE1A	ENSP00000335358	ENSP00000334869	late cornified envelope 3B; Precursors of the cornified envelope of the stratum corneum	late cornified envelope 1A; Precursors of the cornified envelope of the stratum corneum	0.745
LCE3B	LCE3C	ENSP00000335358	ENSP00000334644	late cornified envelope 3B; Precursors of the cornified envelope of the stratum corneum	late cornified envelope 3C; Precursors of the cornified envelope of the stratum corneum	0.925
LCE3B	PGLYRP3	ENSP00000335358	ENSP00000290722	late cornified envelope 3B; Precursors of the cornified envelope of the stratum corneum	peptidoglycan recognition protein 3; Pattern receptor that binds to murein peptidoglycans (PGN) of Gram-positive bacteria. Has bactericidal activity towards Gram-positive bacteria. May kill Gram-positive bacteria by interfering with peptidoglycan biosynthesis. Binds also to Gram- negative bacteria, and has bacteriostatic activity towards Gram- negative bacteria. Plays a role in innate immunity	0.680

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