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STRINGSTRING
TRAPPC4 TRAPPC4 TSPO TSPO UBC UBC PNPO PNPO WDR4 WDR4 AOX1 AOX1 PDXP PDXP PDXK PDXK PHOSPHO2 PHOSPHO2 TEF TEF DBP DBP
"PDXK" - pyridoxal (pyridoxine, vitamin B6) kinase in Homo sapiens
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protein of unknown 3D structure
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Predicted Interactions
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PDXKpyridoxal (pyridoxine, vitamin B6) kinase; Required for synthesis of pyridoxal-5-phosphate from vitamin B6 (312 aa)    
Predicted Functional Partners:
PNPO
pyridoxamine 5’-phosphate oxidase; Catalyzes the oxidation of either pyridoxine 5’- phosphate (PNP) or pyridoxamine 5’-phosphate (PMP) into pyridoxal 5’-phosphate (PLP) (261 aa)
          score_image score_image   0.986
UBC
ubiquitin C (685 aa)
        score_image       0.953
AOX1
aldehyde oxidase 1 (1338 aa)
          score_image     0.900
PDXP
pyridoxal (pyridoxine, vitamin B6) phosphatase; Protein serine phosphatase that dephosphorylates ’Ser-3’ in cofilin and probably also dephosphorylates phospho-serine residues in DSTN. Regulates cofilin-dependent actin cytoskeleton reorganization. Required for normal progress through mitosis and normal cytokinesis. Does not dephosphorylate phospho-threonines in LIMK1. Does not dephosphorylate peptides containing phospho- tyrosine. Pyridoxal phosphate phosphatase. Has some activity towards pyridoxal 5’-phosphate (PLP), pyridoxine 5’-phosphate (PMP) and pyridoxine 5’-phosphate (PNP), with [...] (296 aa)
          score_image score_image   0.844
PHOSPHO2
phosphatase, orphan 2; Phosphatase that has high activity toward pyridoxal 5’- phosphate (PLP). Also active at much lower level toward pyrophosphate, phosphoethanolamine (PEA), phosphocholine (PCho), phospho-l-tyrosine, fructose-6-phosphate, p-nitrophenyl phosphate, and h-glycerophosphate (241 aa)
          score_image     0.800
TEF
thyrotrophic embryonic factor; Transcription factor that binds to and transactivates the TSHB promoter. Binds to a minimal DNA-binding sequence 5’- [TC][AG][AG]TTA[TC][AG]-3’ (303 aa)
            score_image   0.687
DBP
D site of albumin promoter (albumin D-box) binding protein; This transcriptional activator recognizes and binds to the sequence 5’-RTTAYGTAAY-3’ found in the promoter of genes such as albumin, CYP2A4 and CYP2A5. It is not essential for circadian rhythm generation, but modulates important clock output genes. May be a direct target for regulation by the circadian pacemaker component clock. May affect circadian period and sleep regulation (325 aa)
            score_image   0.632
WDR4
WD repeat domain 4; Required for the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA. In the complex, it is required to stabilize and induce conformational change of the catalytic subunit (412 aa)
            score_image   0.583
TSPO
translocator protein (18kDa); Responsible for the manifestation of peripheral-type benzodiazepine recognition sites and is most likely to comprise binding domains for benzodiazepines and isoquinoline carboxamides. May play a role in the transport of porphyrins and heme. Plays a role in the transport of cholesterol across mitochondrial membranes in steroidogenic cells (By similarity) (169 aa)
            score_image   0.580
TRAPPC4
trafficking protein particle complex 4; May play a role in vesicular transport from endoplasmic reticulum to Golgi (219 aa)
            score_image   0.561
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man
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