PEAR1 protein (Homo sapiens) - STRING network view

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PEAR1

platelet endothelial aggregation receptor 1; When overexpressed, reduces the number of both early and late non-adherent myeloid progenitor cells (By similarity) (1037 aa)

Predicted Functional Partners:

SHC2

0.755

GULP1

0.651

TMCC2

0.623

KLHDC1

0.612

KLHDC2

0.606

KLHDC10

0.601

FBXO42

0.587

RABEPK

0.587

CORO2B

0.585

KLHDC9

0.585

Your Current Organism:

Homo sapiens

NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man

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a tab-delimited file describing the names, domains and annotated functions of the network proteins

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CORO2B	FBXO42	ENSP00000454783	ENSP00000364742	coronin, actin binding protein, 2B; May play a role in the reorganization of neuronal actin structure	F-box protein 42; Substrate-recognition component of some SCF (SKP1-CUL1- F-box protein)-type E3 ubiquitin ligase complex. Specifically recognizes p53/TP53, promoting its ubiquitination and degradation	0.585
CORO2B	KLHDC1	ENSP00000454783	ENSP00000352282	coronin, actin binding protein, 2B; May play a role in the reorganization of neuronal actin structure	kelch domain containing 1	0.585
CORO2B	KLHDC10	ENSP00000454783	ENSP00000334140	coronin, actin binding protein, 2B; May play a role in the reorganization of neuronal actin structure	kelch domain containing 10	0.585
CORO2B	KLHDC2	ENSP00000454783	ENSP00000298307	coronin, actin binding protein, 2B; May play a role in the reorganization of neuronal actin structure	kelch domain containing 2; Represses CREB3-mediated transcription by interfering with CREB3-DNA binding	0.585
CORO2B	KLHDC9	ENSP00000454783	ENSP00000356990	coronin, actin binding protein, 2B; May play a role in the reorganization of neuronal actin structure	kelch domain containing 9	0.585
CORO2B	PEAR1	ENSP00000454783	ENSP00000292357	coronin, actin binding protein, 2B; May play a role in the reorganization of neuronal actin structure	platelet endothelial aggregation receptor 1; When overexpressed, reduces the number of both early and late non-adherent myeloid progenitor cells (By similarity)	0.585
CORO2B	RABEPK	ENSP00000454783	ENSP00000362639	coronin, actin binding protein, 2B; May play a role in the reorganization of neuronal actin structure	Rab9 effector protein with kelch motifs	0.585
FBXO42	CORO2B	ENSP00000364742	ENSP00000454783	F-box protein 42; Substrate-recognition component of some SCF (SKP1-CUL1- F-box protein)-type E3 ubiquitin ligase complex. Specifically recognizes p53/TP53, promoting its ubiquitination and degradation	coronin, actin binding protein, 2B; May play a role in the reorganization of neuronal actin structure	0.585
FBXO42	PEAR1	ENSP00000364742	ENSP00000292357	F-box protein 42; Substrate-recognition component of some SCF (SKP1-CUL1- F-box protein)-type E3 ubiquitin ligase complex. Specifically recognizes p53/TP53, promoting its ubiquitination and degradation	platelet endothelial aggregation receptor 1; When overexpressed, reduces the number of both early and late non-adherent myeloid progenitor cells (By similarity)	0.587
GULP1	PEAR1	ENSP00000352047	ENSP00000292357	GULP, engulfment adaptor PTB domain containing 1	platelet endothelial aggregation receptor 1; When overexpressed, reduces the number of both early and late non-adherent myeloid progenitor cells (By similarity)	0.651
KLHDC1	CORO2B	ENSP00000352282	ENSP00000454783	kelch domain containing 1	coronin, actin binding protein, 2B; May play a role in the reorganization of neuronal actin structure	0.585
KLHDC1	PEAR1	ENSP00000352282	ENSP00000292357	kelch domain containing 1	platelet endothelial aggregation receptor 1; When overexpressed, reduces the number of both early and late non-adherent myeloid progenitor cells (By similarity)	0.612
KLHDC10	CORO2B	ENSP00000334140	ENSP00000454783	kelch domain containing 10	coronin, actin binding protein, 2B; May play a role in the reorganization of neuronal actin structure	0.585
KLHDC10	PEAR1	ENSP00000334140	ENSP00000292357	kelch domain containing 10	platelet endothelial aggregation receptor 1; When overexpressed, reduces the number of both early and late non-adherent myeloid progenitor cells (By similarity)	0.601
KLHDC2	CORO2B	ENSP00000298307	ENSP00000454783	kelch domain containing 2; Represses CREB3-mediated transcription by interfering with CREB3-DNA binding	coronin, actin binding protein, 2B; May play a role in the reorganization of neuronal actin structure	0.585
KLHDC2	PEAR1	ENSP00000298307	ENSP00000292357	kelch domain containing 2; Represses CREB3-mediated transcription by interfering with CREB3-DNA binding	platelet endothelial aggregation receptor 1; When overexpressed, reduces the number of both early and late non-adherent myeloid progenitor cells (By similarity)	0.606
KLHDC9	CORO2B	ENSP00000356990	ENSP00000454783	kelch domain containing 9	coronin, actin binding protein, 2B; May play a role in the reorganization of neuronal actin structure	0.585
KLHDC9	PEAR1	ENSP00000356990	ENSP00000292357	kelch domain containing 9	platelet endothelial aggregation receptor 1; When overexpressed, reduces the number of both early and late non-adherent myeloid progenitor cells (By similarity)	0.585
PEAR1	CORO2B	ENSP00000292357	ENSP00000454783	platelet endothelial aggregation receptor 1; When overexpressed, reduces the number of both early and late non-adherent myeloid progenitor cells (By similarity)	coronin, actin binding protein, 2B; May play a role in the reorganization of neuronal actin structure	0.585
PEAR1	FBXO42	ENSP00000292357	ENSP00000364742	platelet endothelial aggregation receptor 1; When overexpressed, reduces the number of both early and late non-adherent myeloid progenitor cells (By similarity)	F-box protein 42; Substrate-recognition component of some SCF (SKP1-CUL1- F-box protein)-type E3 ubiquitin ligase complex. Specifically recognizes p53/TP53, promoting its ubiquitination and degradation	0.587

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