Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Size
small nodes:
protein of unknown 3D structure
protein of unknown 3D structure
large nodes:
some 3D structure is known or predicted
some 3D structure is known or predicted
Node Color
colored nodes:
query proteins and first shell of interactors
query proteins and first shell of interactors
white nodes:
second shell of interactors
second shell of interactors
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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Your Input:
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Neighborhood |
Gene Fusion |
Cooccurence |
Coexpression |
Experiments |
Databases |
Textmining |
[Homology] |
Score |
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 | YDJC | YdjC homolog (bacterial) (323 aa) | ||||||||||||
Predicted Functional Partners:
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 | ZNF831 | zinc finger protein 831 (1677 aa) |
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0.531 | ||||||||||
 | RIMBP3 | RIMS binding protein 3 (1639 aa) |
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0.502 | ||||||||||
 | UBC | ubiquitin C (685 aa) |
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0.483 | ||||||||||
 | MUC19 | mucin 19, oligomeric; May function in ocular mucus homeostasis (1640 aa) |
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0.459 | ||||||||||
 | UGCG | UDP-glucose ceramide glucosyltransferase; Catalyzes the first glycosylation step in glycosphingolipid biosynthesis, the transfer of glucose to ceramide. May also serve as a "flippase" (394 aa) |
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0.452 | ||||||||
 | C17orf51 | chromosome 17 open reading frame 51 (221 aa) |
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0.420 | ||||||||||
 | CDRT15L2 | CMT1A duplicated region transcript 15-like 2 (281 aa) |
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0.420 | ||||||||||
 | CCDC144NL | coiled-coil domain containing 144 family, N-terminal like (221 aa) |
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0.420 | ||||||||||
 | LGALS9B | lectin, galactoside-binding, soluble, 9B; Binds galactosides (By similarity) (355 aa) |
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0.420 | ||||||||||
 | ZPBP2 | zona pellucida binding protein 2; May be implicated in gamete interaction during fertilization (338 aa) |
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0.414 | ||||||||||
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man
Other names: H. sapiens, Homo, Homo sapiens, human, man
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