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STRINGSTRING
DERA DERA ACLY ACLY H6PD H6PD ACACA ACACA RAB3IL1 RAB3IL1 ALDH16A1 ALDH16A1 ACACB ACACB UBC UBC SPG21 SPG21 USP1 USP1 PIH1D1 PIH1D1
"ALDH16A1" - aldehyde dehydrogenase 16 family, member A1 in Homo sapiens
Nodes:
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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small nodes:
protein of unknown 3D structure
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some 3D structure is known or predicted
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query proteins and first shell of interactors
non-colored protein node
white nodes:
second shell of interactors
Edges:
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Known Interactions
database edge
from curated databases
experiment edge
experimentally determined
Predicted Interactions
neighborhood edge
gene neighborhood
fusion edge
gene fusions
cooccurrence edge
gene co-occurrence
Others
textmining edge
textmining
coexpression edge
co-expression
homology edge
protein homology
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[Homology]
Score
ALDH16A1aldehyde dehydrogenase 16 family, member A1 (802 aa)    
Predicted Functional Partners:
UBC
ubiquitin C (685 aa)
        score_image       0.916
SPG21
spastic paraplegia 21 (autosomal recessive, Mast syndrome); May play a role as a negative regulatory factor in CD4- dependent T-cell activation (308 aa)
            score_image   0.757
USP1
ubiquitin specific peptidase 1; Negative regulator of DNA damage repair which specifically deubiquitinates monoubiquitinated FANCD2. Also involved in PCNA-mediated translesion synthesis (TLS) by deubiquitinating monoubiquitinated PCNA. Has almost no deubiquitinating activity by itself and requires the interaction with WDR48 to have a high activity (785 aa)
        score_image       0.740
PIH1D1
PIH1 domain containing 1 (290 aa)
            score_image   0.719
DERA
deoxyribose-phosphate aldolase (putative); Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate (By similarity) (318 aa)
score_image   score_image   score_image       0.703
ACLY
ATP citrate lyase; ATP citrate-lyase is the primary enzyme responsible for the synthesis of cytosolic acetyl-CoA in many tissues. Has a central role in de novo lipid synthesis. In nervous tissue it may be involved in the biosynthesis of acetylcholine (1101 aa)
score_image     score_image     score_image   0.702
RAB3IL1
RAB3A interacting protein (rabin3)-like 1; Guanine nucleotide exchange factor (GEF) which may activate RAB3A, a GTPase that regulates synaptic vesicle exocytosis. Promotes the exchange of GDP to GTP, converting inactive GDP-bound Rab proteins into their active GTP-bound form. May also activate RAB8A and RAB8B (382 aa)
            score_image   0.638
ACACA
acetyl-CoA carboxylase alpha (2383 aa)
        score_image   score_image   0.632
ACACB
acetyl-CoA carboxylase beta; ACC-beta may be involved in the provision of malonyl-CoA or in the regulation of fatty acid oxidation, rather than fatty acid biosynthesis. Carries out three functions- biotin carboxyl carrier protein, biotin carboxylase and carboxyltransferase (2458 aa)
        score_image   score_image   0.632
H6PD
hexose-6-phosphate dehydrogenase (glucose 1-dehydrogenase); Oxidizes glucose-6-phosphate and glucose, as well as other hexose-6-phosphates (791 aa)
      score_image score_image   score_image   0.592
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man
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