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STRINGSTRING
ATXN2 ATXN2 ATXN2L ATXN2L LSM14A LSM14A UBC UBC LSM14B LSM14B LSM3 LSM3 LSM12 LSM12 LSM2 LSM2 EDC3 EDC3 LSM1 LSM1 ZCCHC4 ZCCHC4
LSM12 homolog (S. cerevisiae) in Homo sapiens
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Size
small protein node
small nodes:
protein of unknown 3D structure
large protein node
large nodes:
some 3D structure is known or predicted
Node Color
colored protein node
colored nodes:
query proteins and first shell of interactors
non-colored protein node
white nodes:
second shell of interactors
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
database edge
from curated databases
experiment edge
experimentally determined
Predicted Interactions
neighborhood edge
gene neighborhood
fusion edge
gene fusions
cooccurrence edge
gene co-occurrence
Others
textmining edge
textmining
coexpression edge
co-expression
homology edge
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LSM12LSM12 homolog (S. cerevisiae) (195 aa)    
Predicted Functional Partners:
ATXN2
ataxin 2; Involved in EGFR trafficking, acting as negative regulator of endocytic EGFR internalization at the plasma membrane (1313 aa)
        score_image   score_image   0.914
ZCCHC4
zinc finger, CCHC domain containing 4; May be a methyltransferase (513 aa)
            score_image   0.910
ATXN2L
ataxin 2-like (1097 aa)
        score_image   score_image   0.882
LSM14B
LSM14B, SCD6 homolog B (S. cerevisiae); May play a role in control of mRNA translation (By similarity) (385 aa)
            score_image   0.853
UBC
ubiquitin C (685 aa)
        score_image       0.810
LSM2
LSM2 homolog, U6 small nuclear RNA associated (S. cerevisiae) (95 aa)
        score_image   score_image   0.796
LSM14A
LSM14A, SCD6 homolog A (S. cerevisiae); Essential for formation of P-bodies, cytoplasmic structures that provide storage sites for non-translating mRNAs (463 aa)
            score_image   0.727
LSM1
LSM1 homolog, U6 small nuclear RNA associated (S. cerevisiae); Plays a role in replication-dependent histone mRNA degradation. Binds specifically to the 3’-terminal U-tract of U6 snRNA (133 aa)
      score_image score_image   score_image   0.726
EDC3
enhancer of mRNA decapping 3 homolog (S. cerevisiae); Binds single-stranded RNA. In the process of mRNA degradation, may play a role in mRNA decapping. May play a role in spermiogenesis and oogenesis (508 aa)
        score_image   score_image   0.708
LSM3
LSM3 homolog, U6 small nuclear RNA associated (S. cerevisiae); Binds specifically to the 3’-terminal U-tract of U6 snRNA (102 aa)
            score_image   0.707
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man
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