| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ASB16 | FAM71A | ENSP00000293414 | ENSP00000294829 | ankyrin repeat and SOCS box containing 16; May be a substrate-recognition component of a SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins (By similarity) | family with sequence similarity 71, member A | 0.480 |
| ASB16 | INSC | ENSP00000293414 | ENSP00000368872 | ankyrin repeat and SOCS box containing 16; May be a substrate-recognition component of a SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins (By similarity) | inscuteable homolog (Drosophila); May function as an adapter linking the Par3 complex to the GPSM1/GPSM2 complex. Involved in spindle orientation during mitosis it may regulate cell proliferation and differentiation in the developing nervous system. May play a role in the asymmetric division of fibroblasts and participate in the process of stratification of the squamous epithelium | 0.447 |
| ASB16 | LRRC43 | ENSP00000293414 | ENSP00000344233 | ankyrin repeat and SOCS box containing 16; May be a substrate-recognition component of a SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins (By similarity) | leucine rich repeat containing 43 | 0.495 |
| ASB16 | MRPL36 | ENSP00000293414 | ENSP00000372093 | ankyrin repeat and SOCS box containing 16; May be a substrate-recognition component of a SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins (By similarity) | mitochondrial ribosomal protein L36; Component of the large subunit of the mitochondrial ribosome (Potential) | 0.459 |
| ASB16 | NEURL | ENSP00000293414 | ENSP00000358795 | ankyrin repeat and SOCS box containing 16; May be a substrate-recognition component of a SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins (By similarity) | neuralized homolog (Drosophila); May function as an E3 ubiquitin-protein ligase to activate monoubiquitination of JAG1, thereby regulating the Notch pathway (By similarity) | 0.585 |
| ASB16 | NEURL1B | ENSP00000293414 | ENSP00000358815 | ankyrin repeat and SOCS box containing 16; May be a substrate-recognition component of a SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins (By similarity) | neuralized homolog 1B (Drosophila); E3 ubiquitin-protein ligase involved in regulation of the Notch pathway through influencing the stability and activity of several Notch ligands | 0.585 |
| ASB16 | PLA2G4B | ENSP00000293414 | ENSP00000396045 | ankyrin repeat and SOCS box containing 16; May be a substrate-recognition component of a SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins (By similarity) | phospholipase A2, group IVB (cytosolic); Calcium-dependent phospholipase A2 that selectively hydrolyzes glycerophospholipids in the sn-2 position with a preference for arachidonoyl phospholipids. Has a much weaker activity than PLA2G4A. Isoform 3 has calcium-dependent activity against palmitoyl-arachidonyl-phosphatidylethanolamine and low level lysophospholipase activity but no activity against phosphatidylcholine. Isoform 5 does have activity against phosphatidylcholine | 0.463 |
| ASB16 | SPATA24 | ENSP00000293414 | ENSP00000414920 | ankyrin repeat and SOCS box containing 16; May be a substrate-recognition component of a SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins (By similarity) | spermatogenesis associated 24; Binds DNA with high affinity but does not bind to TATA boxes. Synergises with GMNN and TBP in activation of TATA box- containing promoters and with GMNN and TBPL1 in activation of the NF1 TATA-less promoter. May play a role in cytoplasm movement and removal during spermiogenesis (By similarity) | 0.479 |
| ASB16 | SUSD3 | ENSP00000293414 | ENSP00000364621 | ankyrin repeat and SOCS box containing 16; May be a substrate-recognition component of a SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins (By similarity) | sushi domain containing 3 | 0.470 |
| ASB16 | TSPO2 | ENSP00000293414 | ENSP00000362255 | ankyrin repeat and SOCS box containing 16; May be a substrate-recognition component of a SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins (By similarity) | translocator protein 2; Binds cholesterol and mediates its redistribution during erythropoiesis which may play a role in erythrocyte maturation | 0.509 |
| FAM71A | ASB16 | ENSP00000294829 | ENSP00000293414 | family with sequence similarity 71, member A | ankyrin repeat and SOCS box containing 16; May be a substrate-recognition component of a SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins (By similarity) | 0.480 |
| FAM71A | LRRC43 | ENSP00000294829 | ENSP00000344233 | family with sequence similarity 71, member A | leucine rich repeat containing 43 | 0.528 |
| FAM71A | SPATA24 | ENSP00000294829 | ENSP00000414920 | family with sequence similarity 71, member A | spermatogenesis associated 24; Binds DNA with high affinity but does not bind to TATA boxes. Synergises with GMNN and TBP in activation of TATA box- containing promoters and with GMNN and TBPL1 in activation of the NF1 TATA-less promoter. May play a role in cytoplasm movement and removal during spermiogenesis (By similarity) | 0.586 |
| FAM71A | TSPO2 | ENSP00000294829 | ENSP00000362255 | family with sequence similarity 71, member A | translocator protein 2; Binds cholesterol and mediates its redistribution during erythropoiesis which may play a role in erythrocyte maturation | 0.414 |
| INSC | ASB16 | ENSP00000368872 | ENSP00000293414 | inscuteable homolog (Drosophila); May function as an adapter linking the Par3 complex to the GPSM1/GPSM2 complex. Involved in spindle orientation during mitosis it may regulate cell proliferation and differentiation in the developing nervous system. May play a role in the asymmetric division of fibroblasts and participate in the process of stratification of the squamous epithelium | ankyrin repeat and SOCS box containing 16; May be a substrate-recognition component of a SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins (By similarity) | 0.447 |
| LRRC43 | ASB16 | ENSP00000344233 | ENSP00000293414 | leucine rich repeat containing 43 | ankyrin repeat and SOCS box containing 16; May be a substrate-recognition component of a SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins (By similarity) | 0.495 |
| LRRC43 | FAM71A | ENSP00000344233 | ENSP00000294829 | leucine rich repeat containing 43 | family with sequence similarity 71, member A | 0.528 |
| LRRC43 | SPATA24 | ENSP00000344233 | ENSP00000414920 | leucine rich repeat containing 43 | spermatogenesis associated 24; Binds DNA with high affinity but does not bind to TATA boxes. Synergises with GMNN and TBP in activation of TATA box- containing promoters and with GMNN and TBPL1 in activation of the NF1 TATA-less promoter. May play a role in cytoplasm movement and removal during spermiogenesis (By similarity) | 0.516 |
| MRPL36 | ASB16 | ENSP00000372093 | ENSP00000293414 | mitochondrial ribosomal protein L36; Component of the large subunit of the mitochondrial ribosome (Potential) | ankyrin repeat and SOCS box containing 16; May be a substrate-recognition component of a SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins (By similarity) | 0.459 |
| NEURL | ASB16 | ENSP00000358795 | ENSP00000293414 | neuralized homolog (Drosophila); May function as an E3 ubiquitin-protein ligase to activate monoubiquitination of JAG1, thereby regulating the Notch pathway (By similarity) | ankyrin repeat and SOCS box containing 16; May be a substrate-recognition component of a SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins (By similarity) | 0.585 |
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