| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| BAIAP3 | CRAMP1L | ENSP00000324510 | ENSP00000293925 | BAI1-associated protein 3 | Crm, cramped-like (Drosophila) | 0.453 |
| CRAMP1L | BAIAP3 | ENSP00000293925 | ENSP00000324510 | Crm, cramped-like (Drosophila) | BAI1-associated protein 3 | 0.453 |
| CRAMP1L | DERL2 | ENSP00000293925 | ENSP00000158771 | Crm, cramped-like (Drosophila) | derlin 2; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal glycoproteins, but not that of misfolded nonglycoproteins. May act by forming a channel that allows the retrotranslocation of misfolded glycoproteins into the cytosol where they are ubiquitinated and degraded by the proteasome. May mediate the interaction between VCP and the degradation substrate. In contrast to DERL1, it is not involved in the degradation of MHC class I heavy chains following infection by cytomegaloviruses. May play a role in cell proliferation | 0.461 |
| CRAMP1L | DERL3 | ENSP00000293925 | ENSP00000384744 | Crm, cramped-like (Drosophila) | derlin 3; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal glycoproteins, but not that of misfolded nonglycoproteins. May act by forming a channel that allows the retrotranslocation of misfolded glycoproteins into the cytosol where they are ubiquitinated and degraded by the proteasome. May mediate the interaction between VCP and the degradation substrate | 0.461 |
| CRAMP1L | HDHD1 | ENSP00000293925 | ENSP00000396452 | Crm, cramped-like (Drosophila) | haloacid dehalogenase-like hydrolase domain containing 1; Dephosphorylates pseudouridine 5’-phosphate, a potential intermediate in rRNA degradation. Pseudouridine is then excreted intact in urine | 0.480 |
| CRAMP1L | HIST2H3D | ENSP00000293925 | ENSP00000333277 | Crm, cramped-like (Drosophila) | histone cluster 2, H3d | 0.485 |
| CRAMP1L | NUBP1 | ENSP00000293925 | ENSP00000283027 | Crm, cramped-like (Drosophila) | nucleotide binding protein 1; Implicated in the regulation of centrosome duplication (By similarity). Component of the cytosolic iron-sulfur (Fe/S) protein assembly (CIA) machinery. Required for maturation of extramitochondrial Fe-S proteins. The NUBP1-NUBP2 heterotetramer forms a Fe-S scaffold complex, mediating the de novo assembly of an Fe-S cluster and its transfer to target apoproteins | 0.449 |
| CRAMP1L | NUBP2 | ENSP00000293925 | ENSP00000262302 | Crm, cramped-like (Drosophila) | nucleotide binding protein 2; Component of the cytosolic iron-sulfur (Fe/S) protein assembly (CIA) machinery. Required for maturation of extramitochondrial Fe-S proteins. The NUBP1-NUBP2 heterotetramer forms a Fe-S scaffold complex, mediating the de novo assembly of an Fe-S cluster and its transfer to target apoproteins (By similarity) | 0.565 |
| CRAMP1L | TRAP1 | ENSP00000293925 | ENSP00000246957 | Crm, cramped-like (Drosophila) | TNF receptor-associated protein 1; Chaperone that expresses an ATPase activity | 0.461 |
| DERL2 | CRAMP1L | ENSP00000158771 | ENSP00000293925 | derlin 2; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal glycoproteins, but not that of misfolded nonglycoproteins. May act by forming a channel that allows the retrotranslocation of misfolded glycoproteins into the cytosol where they are ubiquitinated and degraded by the proteasome. May mediate the interaction between VCP and the degradation substrate. In contrast to DERL1, it is not involved in the degradation of MHC class I heavy chains following infection by cytomegaloviruses. May play a role in cell proliferation | Crm, cramped-like (Drosophila) | 0.461 |
| DERL2 | HDHD1 | ENSP00000158771 | ENSP00000396452 | derlin 2; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal glycoproteins, but not that of misfolded nonglycoproteins. May act by forming a channel that allows the retrotranslocation of misfolded glycoproteins into the cytosol where they are ubiquitinated and degraded by the proteasome. May mediate the interaction between VCP and the degradation substrate. In contrast to DERL1, it is not involved in the degradation of MHC class I heavy chains following infection by cytomegaloviruses. May play a role in cell proliferation | haloacid dehalogenase-like hydrolase domain containing 1; Dephosphorylates pseudouridine 5’-phosphate, a potential intermediate in rRNA degradation. Pseudouridine is then excreted intact in urine | 0.461 |
| DERL2 | TRAP1 | ENSP00000158771 | ENSP00000246957 | derlin 2; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal glycoproteins, but not that of misfolded nonglycoproteins. May act by forming a channel that allows the retrotranslocation of misfolded glycoproteins into the cytosol where they are ubiquitinated and degraded by the proteasome. May mediate the interaction between VCP and the degradation substrate. In contrast to DERL1, it is not involved in the degradation of MHC class I heavy chains following infection by cytomegaloviruses. May play a role in cell proliferation | TNF receptor-associated protein 1; Chaperone that expresses an ATPase activity | 0.459 |
| DERL3 | CRAMP1L | ENSP00000384744 | ENSP00000293925 | derlin 3; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal glycoproteins, but not that of misfolded nonglycoproteins. May act by forming a channel that allows the retrotranslocation of misfolded glycoproteins into the cytosol where they are ubiquitinated and degraded by the proteasome. May mediate the interaction between VCP and the degradation substrate | Crm, cramped-like (Drosophila) | 0.461 |
| DERL3 | HDHD1 | ENSP00000384744 | ENSP00000396452 | derlin 3; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal glycoproteins, but not that of misfolded nonglycoproteins. May act by forming a channel that allows the retrotranslocation of misfolded glycoproteins into the cytosol where they are ubiquitinated and degraded by the proteasome. May mediate the interaction between VCP and the degradation substrate | haloacid dehalogenase-like hydrolase domain containing 1; Dephosphorylates pseudouridine 5’-phosphate, a potential intermediate in rRNA degradation. Pseudouridine is then excreted intact in urine | 0.461 |
| DERL3 | TRAP1 | ENSP00000384744 | ENSP00000246957 | derlin 3; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal glycoproteins, but not that of misfolded nonglycoproteins. May act by forming a channel that allows the retrotranslocation of misfolded glycoproteins into the cytosol where they are ubiquitinated and degraded by the proteasome. May mediate the interaction between VCP and the degradation substrate | TNF receptor-associated protein 1; Chaperone that expresses an ATPase activity | 0.459 |
| HDHD1 | CRAMP1L | ENSP00000396452 | ENSP00000293925 | haloacid dehalogenase-like hydrolase domain containing 1; Dephosphorylates pseudouridine 5’-phosphate, a potential intermediate in rRNA degradation. Pseudouridine is then excreted intact in urine | Crm, cramped-like (Drosophila) | 0.480 |
| HDHD1 | DERL2 | ENSP00000396452 | ENSP00000158771 | haloacid dehalogenase-like hydrolase domain containing 1; Dephosphorylates pseudouridine 5’-phosphate, a potential intermediate in rRNA degradation. Pseudouridine is then excreted intact in urine | derlin 2; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal glycoproteins, but not that of misfolded nonglycoproteins. May act by forming a channel that allows the retrotranslocation of misfolded glycoproteins into the cytosol where they are ubiquitinated and degraded by the proteasome. May mediate the interaction between VCP and the degradation substrate. In contrast to DERL1, it is not involved in the degradation of MHC class I heavy chains following infection by cytomegaloviruses. May play a role in cell proliferation | 0.461 |
| HDHD1 | DERL3 | ENSP00000396452 | ENSP00000384744 | haloacid dehalogenase-like hydrolase domain containing 1; Dephosphorylates pseudouridine 5’-phosphate, a potential intermediate in rRNA degradation. Pseudouridine is then excreted intact in urine | derlin 3; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal glycoproteins, but not that of misfolded nonglycoproteins. May act by forming a channel that allows the retrotranslocation of misfolded glycoproteins into the cytosol where they are ubiquitinated and degraded by the proteasome. May mediate the interaction between VCP and the degradation substrate | 0.461 |
| HDHD1 | TRAP1 | ENSP00000396452 | ENSP00000246957 | haloacid dehalogenase-like hydrolase domain containing 1; Dephosphorylates pseudouridine 5’-phosphate, a potential intermediate in rRNA degradation. Pseudouridine is then excreted intact in urine | TNF receptor-associated protein 1; Chaperone that expresses an ATPase activity | 0.461 |
| HIST2H3D | CRAMP1L | ENSP00000333277 | ENSP00000293925 | histone cluster 2, H3d | Crm, cramped-like (Drosophila) | 0.485 |
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