USP24 protein (Homo sapiens) - STRING network view

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USP24

ubiquitin specific peptidase 24; Involved in the ubiquitin-dependent proteolytic pathway in conjunction with the 26S proteasome (By similarity) (2620 aa)

Predicted Functional Partners:

UBC

0.983

DDB2

0.920

CDCP2

0.860

GMPS

0.796

CLINT1

0.767

EPN1

0.767

EPN2

0.767

ENTHD1

0.767

EPN3

0.767

HIVEP3

0.759

Your Current Organism:

Homo sapiens

NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CDCP2	HIVEP3	ENSP00000360381	ENSP00000247584	CUB domain containing protein 2	human immunodeficiency virus type I enhancer binding protein 3; Plays a role of transcription factor; binds to recognition signal sequences (Rss heptamer) for somatic recombination of immunoglobulin and T-cell receptor gene segments; Binds also to the kappa-B motif of gene such as S100A4, involved in cell progression and differentiation. Kappa-B motif is a gene regulatory element found in promoters and enhancers of genes involved in immunity, inflammation, and growth and that responds to viral antigens, mitogens, and cytokines. Involvement of HIVEP3 in cell growth is strengthened by th [...]	0.759
CDCP2	USP24	ENSP00000360381	ENSP00000294383	CUB domain containing protein 2	ubiquitin specific peptidase 24; Involved in the ubiquitin-dependent proteolytic pathway in conjunction with the 26S proteasome (By similarity)	0.860
CLINT1	UBC	ENSP00000429824	ENSP00000344818	clathrin interactor 1; Binds to membranes enriched in phosphatidylinositol 4,5- bisphosphate (PtdIns(4,5)P2). May have a role in transport via clathrin-coated vesicles from the trans-Golgi network to endosomes. Stimulates clathrin assembly	ubiquitin C	0.982
CLINT1	USP24	ENSP00000429824	ENSP00000294383	clathrin interactor 1; Binds to membranes enriched in phosphatidylinositol 4,5- bisphosphate (PtdIns(4,5)P2). May have a role in transport via clathrin-coated vesicles from the trans-Golgi network to endosomes. Stimulates clathrin assembly	ubiquitin specific peptidase 24; Involved in the ubiquitin-dependent proteolytic pathway in conjunction with the 26S proteasome (By similarity)	0.767
DDB2	UBC	ENSP00000256996	ENSP00000344818	damage-specific DNA binding protein 2, 48kDa; Required for DNA repair. Binds to DDB1 to form the UV- damaged DNA-binding protein complex (the UV-DDB complex). The UV- DDB complex may recognize UV-induced DNA damage and recruit proteins of the nucleotide excision repair pathway (the NER pathway) to initiate DNA repair. The UV-DDB complex preferentially binds to cyclobutane pyrimidine dimers (CPD), 6-4 photoproducts (6-4 PP), apurinic sites and short mismatches. Also appears to function as the substrate recognition module for the DCX (DDB1- CUL4-X-box) E3 ubiquitin-protein ligase complex [...]	ubiquitin C	0.980
DDB2	USP24	ENSP00000256996	ENSP00000294383	damage-specific DNA binding protein 2, 48kDa; Required for DNA repair. Binds to DDB1 to form the UV- damaged DNA-binding protein complex (the UV-DDB complex). The UV- DDB complex may recognize UV-induced DNA damage and recruit proteins of the nucleotide excision repair pathway (the NER pathway) to initiate DNA repair. The UV-DDB complex preferentially binds to cyclobutane pyrimidine dimers (CPD), 6-4 photoproducts (6-4 PP), apurinic sites and short mismatches. Also appears to function as the substrate recognition module for the DCX (DDB1- CUL4-X-box) E3 ubiquitin-protein ligase complex [...]	ubiquitin specific peptidase 24; Involved in the ubiquitin-dependent proteolytic pathway in conjunction with the 26S proteasome (By similarity)	0.920
ENTHD1	USP24	ENSP00000317431	ENSP00000294383	ENTH domain containing 1	ubiquitin specific peptidase 24; Involved in the ubiquitin-dependent proteolytic pathway in conjunction with the 26S proteasome (By similarity)	0.767
EPN1	EPN3	ENSP00000406209	ENSP00000268933	epsin 1; Binds to membranes enriched in phosphatidylinositol 4,5- bisphosphate (PtdIns(4,5)P2). Modifies membrane curvature and facilitates the formation of clathrin-coated invaginations (By similarity). Regulates receptor-mediated endocytosis	epsin 3	0.613
EPN1	UBC	ENSP00000406209	ENSP00000344818	epsin 1; Binds to membranes enriched in phosphatidylinositol 4,5- bisphosphate (PtdIns(4,5)P2). Modifies membrane curvature and facilitates the formation of clathrin-coated invaginations (By similarity). Regulates receptor-mediated endocytosis	ubiquitin C	0.999
EPN1	USP24	ENSP00000406209	ENSP00000294383	epsin 1; Binds to membranes enriched in phosphatidylinositol 4,5- bisphosphate (PtdIns(4,5)P2). Modifies membrane curvature and facilitates the formation of clathrin-coated invaginations (By similarity). Regulates receptor-mediated endocytosis	ubiquitin specific peptidase 24; Involved in the ubiquitin-dependent proteolytic pathway in conjunction with the 26S proteasome (By similarity)	0.767
EPN2	UBC	ENSP00000320543	ENSP00000344818	epsin 2; Plays a role in the formation of clathrin-coated invaginations and endocytosis	ubiquitin C	0.945
EPN2	USP24	ENSP00000320543	ENSP00000294383	epsin 2; Plays a role in the formation of clathrin-coated invaginations and endocytosis	ubiquitin specific peptidase 24; Involved in the ubiquitin-dependent proteolytic pathway in conjunction with the 26S proteasome (By similarity)	0.767
EPN3	EPN1	ENSP00000268933	ENSP00000406209	epsin 3	epsin 1; Binds to membranes enriched in phosphatidylinositol 4,5- bisphosphate (PtdIns(4,5)P2). Modifies membrane curvature and facilitates the formation of clathrin-coated invaginations (By similarity). Regulates receptor-mediated endocytosis	0.613
EPN3	UBC	ENSP00000268933	ENSP00000344818	epsin 3	ubiquitin C	0.748
EPN3	USP24	ENSP00000268933	ENSP00000294383	epsin 3	ubiquitin specific peptidase 24; Involved in the ubiquitin-dependent proteolytic pathway in conjunction with the 26S proteasome (By similarity)	0.767
GMPS	UBC	ENSP00000419851	ENSP00000344818	guanine monphosphate synthetase; Involved in the de novo synthesis of guanine nucleotides which are not only essential for DNA and RNA synthesis, but also provide GTP, which is involved in a number of cellular processes important for cell division	ubiquitin C	0.983
GMPS	USP24	ENSP00000419851	ENSP00000294383	guanine monphosphate synthetase; Involved in the de novo synthesis of guanine nucleotides which are not only essential for DNA and RNA synthesis, but also provide GTP, which is involved in a number of cellular processes important for cell division	ubiquitin specific peptidase 24; Involved in the ubiquitin-dependent proteolytic pathway in conjunction with the 26S proteasome (By similarity)	0.796
HIVEP3	CDCP2	ENSP00000247584	ENSP00000360381	human immunodeficiency virus type I enhancer binding protein 3; Plays a role of transcription factor; binds to recognition signal sequences (Rss heptamer) for somatic recombination of immunoglobulin and T-cell receptor gene segments; Binds also to the kappa-B motif of gene such as S100A4, involved in cell progression and differentiation. Kappa-B motif is a gene regulatory element found in promoters and enhancers of genes involved in immunity, inflammation, and growth and that responds to viral antigens, mitogens, and cytokines. Involvement of HIVEP3 in cell growth is strengthened by th [...]	CUB domain containing protein 2	0.759
HIVEP3	UBC	ENSP00000247584	ENSP00000344818	human immunodeficiency virus type I enhancer binding protein 3; Plays a role of transcription factor; binds to recognition signal sequences (Rss heptamer) for somatic recombination of immunoglobulin and T-cell receptor gene segments; Binds also to the kappa-B motif of gene such as S100A4, involved in cell progression and differentiation. Kappa-B motif is a gene regulatory element found in promoters and enhancers of genes involved in immunity, inflammation, and growth and that responds to viral antigens, mitogens, and cytokines. Involvement of HIVEP3 in cell growth is strengthened by th [...]	ubiquitin C	0.750
HIVEP3	USP24	ENSP00000247584	ENSP00000294383	human immunodeficiency virus type I enhancer binding protein 3; Plays a role of transcription factor; binds to recognition signal sequences (Rss heptamer) for somatic recombination of immunoglobulin and T-cell receptor gene segments; Binds also to the kappa-B motif of gene such as S100A4, involved in cell progression and differentiation. Kappa-B motif is a gene regulatory element found in promoters and enhancers of genes involved in immunity, inflammation, and growth and that responds to viral antigens, mitogens, and cytokines. Involvement of HIVEP3 in cell growth is strengthened by th [...]	ubiquitin specific peptidase 24; Involved in the ubiquitin-dependent proteolytic pathway in conjunction with the 26S proteasome (By similarity)	0.759

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