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STRINGSTRING
ZNF330 ZNF330 TMEM80 TMEM80 TXNDC5 TXNDC5 PPP1R21 PPP1R21 KIAA0556 KIAA0556 GTF3C6 GTF3C6 COMTD1 COMTD1 SOWAHA SOWAHA
"PPP1R21" - protein phosphatase 1, regulatory subunit 21 in Homo sapiens
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Size
small protein node
small nodes:
protein of unknown 3D structure
large protein node
large nodes:
some 3D structure is known or predicted
Node Color
colored protein node
colored nodes:
query proteins and first shell of interactors
non-colored protein node
white nodes:
second shell of interactors
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
database edge
from curated databases
experiment edge
experimentally determined
Predicted Interactions
neighborhood edge
gene neighborhood
fusion edge
gene fusions
cooccurrence edge
gene co-occurrence
Others
textmining edge
textmining
coexpression edge
co-expression
homology edge
protein homology
Your Input:
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Cooccurence
Coexpression
Experiments
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Textmining
[Homology]
Score
PPP1R21protein phosphatase 1, regulatory subunit 21 (780 aa)    
Predicted Functional Partners:
TXNDC5
thioredoxin domain containing 5 (endoplasmic reticulum); Possesses thioredoxin activity. Has been shown to reduce insulin disulfide bonds. Also complements protein disulfide- isomerase deficiency in yeast (By similarity) (432 aa)
        score_image       0.644
ZNF330
zinc finger protein 330 (320 aa)
            score_image   0.584
TMEM80
transmembrane protein 80 (168 aa)
            score_image   0.570
GTF3C6
general transcription factor IIIC, polypeptide 6, alpha 35kDa; Involved in RNA polymerase III-mediated transcription. Integral, tightly associated component of the DNA-binding TFIIIC2 subcomplex that directly binds tRNA and virus-associated RNA promoters (213 aa)
            score_image   0.507
SOWAHA
sosondowah ankyrin repeat domain family member A (549 aa)
            score_image   0.499
KIAA0556
KIAA0556 (1618 aa)
            score_image   0.472
COMTD1
catechol-O-methyltransferase domain containing 1; Putative O-methyltransferase (Potential) (262 aa)
            score_image   0.405
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man
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