WDR92 protein (Homo sapiens) - STRING network view

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WDR92

WD repeat domain 92; Seems to act as a modulator of apoptosis (357 aa)

Predicted Functional Partners:

RPAP3

0.927

ZNF853

0.644

S100A10

0.644

PMVK

0.644

UBC

0.620

AREG

0.576

EXOSC8

0.576

SETD1A

0.571

PPP3CB

0.538

WDR36

0.537

Your Current Organism:

Homo sapiens

NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AREG	WDR92	ENSP00000264487	ENSP00000295121	amphiregulin	WD repeat domain 92; Seems to act as a modulator of apoptosis	0.576
EXOSC8	UBC	ENSP00000374354	ENSP00000344818	exosome component 8; Non-catalytic component of the RNA exosome complex which has 3’->5’ exoribonuclease activity and participates in a multitude of cellular RNA processing and degradation events. In the nucleus, the RNA exosome complex is involved in proper maturation of stable RNA species such as rRNA, snRNA and snoRNA, in the elimination of RNA processing by-products and non-coding ’pervasive’ transcripts, such as antisense RNA species and promoter-upstream transcripts (PROMPTs), and of mRNAs with processing defects, thereby limiting or excluding their export to the cytoplasm. The R [...]	ubiquitin C	0.809
EXOSC8	WDR92	ENSP00000374354	ENSP00000295121	exosome component 8; Non-catalytic component of the RNA exosome complex which has 3’->5’ exoribonuclease activity and participates in a multitude of cellular RNA processing and degradation events. In the nucleus, the RNA exosome complex is involved in proper maturation of stable RNA species such as rRNA, snRNA and snoRNA, in the elimination of RNA processing by-products and non-coding ’pervasive’ transcripts, such as antisense RNA species and promoter-upstream transcripts (PROMPTs), and of mRNAs with processing defects, thereby limiting or excluding their export to the cytoplasm. The R [...]	WD repeat domain 92; Seems to act as a modulator of apoptosis	0.576
PMVK	UBC	ENSP00000357452	ENSP00000344818	phosphomevalonate kinase	ubiquitin C	0.892
PMVK	WDR92	ENSP00000357452	ENSP00000295121	phosphomevalonate kinase	WD repeat domain 92; Seems to act as a modulator of apoptosis	0.644
PPP3CB	UBC	ENSP00000378306	ENSP00000344818	protein phosphatase 3, catalytic subunit, beta isozyme; Calcium-dependent, calmodulin-stimulated protein phosphatase. This subunit may have a role in the calmodulin activation of calcineurin	ubiquitin C	0.815
PPP3CB	WDR92	ENSP00000378306	ENSP00000295121	protein phosphatase 3, catalytic subunit, beta isozyme; Calcium-dependent, calmodulin-stimulated protein phosphatase. This subunit may have a role in the calmodulin activation of calcineurin	WD repeat domain 92; Seems to act as a modulator of apoptosis	0.538
RPAP3	UBC	ENSP00000005386	ENSP00000344818	RNA polymerase II associated protein 3; Forms an interface between the RNA polymerase II enzyme and chaperone/scaffolding protein, suggesting that it is required to connect RNA polymerase II to regulators of protein complex formation	ubiquitin C	0.483
RPAP3	WDR92	ENSP00000005386	ENSP00000295121	RNA polymerase II associated protein 3; Forms an interface between the RNA polymerase II enzyme and chaperone/scaffolding protein, suggesting that it is required to connect RNA polymerase II to regulators of protein complex formation	WD repeat domain 92; Seems to act as a modulator of apoptosis	0.927
S100A10	UBC	ENSP00000357799	ENSP00000344818	S100 calcium binding protein A10; Because S100A10 induces the dimerization of ANXA2/p36, it may function as a regulator of protein phosphorylation in that the ANXA2 monomer is the preferred target (in vitro) of tyrosine- specific kinase	ubiquitin C	0.978
S100A10	WDR92	ENSP00000357799	ENSP00000295121	S100 calcium binding protein A10; Because S100A10 induces the dimerization of ANXA2/p36, it may function as a regulator of protein phosphorylation in that the ANXA2 monomer is the preferred target (in vitro) of tyrosine- specific kinase	WD repeat domain 92; Seems to act as a modulator of apoptosis	0.644
SETD1A	WDR92	ENSP00000262519	ENSP00000295121	SET domain containing 1A; Histone methyltransferase that specifically methylates ’Lys-4’ of histone H3, when part of the SET1 histone methyltransferase (HMT) complex, but not if the neighboring ’Lys- 9’ residue is already methylated. H3 ’Lys-4’ methylation represents a specific tag for epigenetic transcriptional activation. The non-overalpping localization with SETD1B suggests that SETD1A and SETD1B make non-redundant contributions to the epigenetic control of chromatin structure and gene expression	WD repeat domain 92; Seems to act as a modulator of apoptosis	0.571
UBC	EXOSC8	ENSP00000344818	ENSP00000374354	ubiquitin C	exosome component 8; Non-catalytic component of the RNA exosome complex which has 3’->5’ exoribonuclease activity and participates in a multitude of cellular RNA processing and degradation events. In the nucleus, the RNA exosome complex is involved in proper maturation of stable RNA species such as rRNA, snRNA and snoRNA, in the elimination of RNA processing by-products and non-coding ’pervasive’ transcripts, such as antisense RNA species and promoter-upstream transcripts (PROMPTs), and of mRNAs with processing defects, thereby limiting or excluding their export to the cytoplasm. The R [...]	0.809
UBC	PMVK	ENSP00000344818	ENSP00000357452	ubiquitin C	phosphomevalonate kinase	0.892
UBC	PPP3CB	ENSP00000344818	ENSP00000378306	ubiquitin C	protein phosphatase 3, catalytic subunit, beta isozyme; Calcium-dependent, calmodulin-stimulated protein phosphatase. This subunit may have a role in the calmodulin activation of calcineurin	0.815
UBC	RPAP3	ENSP00000344818	ENSP00000005386	ubiquitin C	RNA polymerase II associated protein 3; Forms an interface between the RNA polymerase II enzyme and chaperone/scaffolding protein, suggesting that it is required to connect RNA polymerase II to regulators of protein complex formation	0.483
UBC	S100A10	ENSP00000344818	ENSP00000357799	ubiquitin C	S100 calcium binding protein A10; Because S100A10 induces the dimerization of ANXA2/p36, it may function as a regulator of protein phosphorylation in that the ANXA2 monomer is the preferred target (in vitro) of tyrosine- specific kinase	0.978
UBC	WDR36	ENSP00000344818	ENSP00000423067	ubiquitin C	WD repeat domain 36; Involved in T-cell activation and highly co-regulated with IL2	0.924
UBC	WDR92	ENSP00000344818	ENSP00000295121	ubiquitin C	WD repeat domain 92; Seems to act as a modulator of apoptosis	0.620
WDR36	UBC	ENSP00000423067	ENSP00000344818	WD repeat domain 36; Involved in T-cell activation and highly co-regulated with IL2	ubiquitin C	0.924

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