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SPATA32 SPATA32 FAM166A FAM166A ODF1 ODF1 SURF6 SURF6 TEKT4 TEKT4 RSPH4A RSPH4A CATSPER2 CATSPER2 KIF6 KIF6 MAGEA4 MAGEA4 CATSPER3 CATSPER3 RSPH6A RSPH6A
"TEKT4" - tektin 4 in Homo sapiens
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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small nodes:
protein of unknown 3D structure
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some 3D structure is known or predicted
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query proteins and first shell of interactors
non-colored protein node
white nodes:
second shell of interactors
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experimentally determined
Predicted Interactions
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Score
TEKT4tektin 4; Structural component of ciliary and flagellar microtubules. Forms filamentous polymers in the walls of ciliary and flagellar microtubules (By similarity) (435 aa)    
Predicted Functional Partners:
RSPH4A
radial spoke head 4 homolog A (Chlamydomonas); Probable component of the axonemal radial spoke head. Radial spokes are regularly spaced along cilia, sperm and flagella axonemes. They consist of a thin stalk which is attached to a subfiber of the outer doublet microtubule, and a bulbous head which is attached to the stalk and appears to interact with the projections from the central pair of microtubules (716 aa)
       score_image     score_image   0.748
SURF6
surfeit 6; Binds to both DNA and RNA in vitro, with a stronger binding capacity for RNA. May represent a nucleolar constitutive protein involved in ribosomal biosynthesis or assembly (By similarity) (361 aa)
             score_image   0.608
KIF6
kinesin family member 6 (814 aa)
             score_image   0.594
RSPH6A
radial spoke head 6 homolog A (Chlamydomonas) (717 aa)
       score_image     score_image   0.588
SPATA32
spermatogenesis associated 32 (384 aa)
             score_image   0.563
MAGEA4
melanoma antigen family A, 4; Not known, though may play a role in embryonal development and tumor transformation or aspects of tumor progression (317 aa)
         score_image       0.530
CATSPER2
cation channel, sperm associated 2; Voltage-gated calcium channel that plays a central role in calcium-dependent physiological responses essential for successful fertilization, such as sperm hyperactivation, acrosome reaction and chemotaxis towards the oocyte. Activated by extracellular progesterone and prostaglandins following the sequence- progesterone > PGF1-alpha = PGE1 > PGA1 > PGE2 >> PGD2. The primary effect of progesterone activation is to shift voltage dependence towards more physiological, negative membrane potentials; it is not mediated by metabotropic receptors and second m [...] (530 aa)
             score_image   0.522
ODF1
outer dense fiber of sperm tails 1; Component of the outer dense fibers (ODF) of spermatozoa. ODF are filamentous structures located on the outside of the axoneme in the midpiece and principal piece of the mammalian sperm tail and may help to maintain the passive elastic structures and elastic recoil of the sperm tail (250 aa)
             score_image   0.509
FAM166A
family with sequence similarity 166, member A (317 aa)
             score_image   0.507
CATSPER3
cation channel, sperm associated 3; Voltage-gated calcium channel that plays a central role in calcium-dependent physiological responses essential for successful fertilization, such as sperm hyperactivation, acrosome reaction and chemotaxis towards the oocyte. Activated by extracellular progesterone and prostaglandins following the sequence- progesterone > PGF1-alpha = PGE1 > PGA1 > PGE2 >> PGD2. The primary effect of progesterone activation is to shift voltage dependence towards more physiological, negative membrane potentials; it is not mediated by metabotropic receptors and second m [...] (398 aa)
             score_image   0.502
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man
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