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STRINGSTRING
COL6A3 COL6A3 COL5A2 COL5A2 COL4A5 COL4A5 COL17A1 COL17A1 COL6A1 COL6A1 COL15A1 COL15A1 COL8A1 COL8A1 COL1A1 COL1A1 COL3A1 COL3A1 COL6A2 COL6A2 COL1A2 COL1A2
"COL6A3" - collagen, type VI, alpha 3 in Homo sapiens
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Size
small protein node
small nodes:
protein of unknown 3D structure
large protein node
large nodes:
some 3D structure is known or predicted
Node Color
colored protein node
colored nodes:
query proteins and first shell of interactors
non-colored protein node
white nodes:
second shell of interactors
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
database edge
from curated databases
experiment edge
experimentally determined
Predicted Interactions
neighborhood edge
gene neighborhood
fusion edge
gene fusions
cooccurrence edge
gene co-occurrence
Others
textmining edge
textmining
coexpression edge
co-expression
homology edge
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
COL6A3collagen, type VI, alpha 3; Collagen VI acts as a cell-binding protein (3177 aa)    
Predicted Functional Partners:
COL15A1
collagen, type XV, alpha 1; Structural protein that stabilizes microvessels and muscle cells, both in heart and in skeletal muscle (1388 aa)
          score_image score_image   0.943
COL6A2
collagen, type VI, alpha 2 (1019 aa)
      score_image   score_image score_image score_image 0.940
COL6A1
collagen, type VI, alpha 1; Collagen VI acts as a cell-binding protein (1028 aa)
      score_image   score_image score_image score_image 0.938
COL8A1
collagen, type VIII, alpha 1; Macromolecular component of the subendothelium. Major component of the Descemet’s membrane (basement membrane) of corneal endothelial cells. Also component of the endothelia of blood vessels. Necessary for migration and proliferation of vascular smooth muscle cells and thus, has a potential role in the maintenance of vessel wall integrity and structure, in particular in atherogenesis (744 aa)
          score_image score_image   0.937
COL4A5
collagen, type IV, alpha 5; Type IV collagen is the major structural component of glomerular basement membranes (GBM), forming a ’chicken-wire’ meshwork together with laminins, proteoglycans and entactin/nidogen (1691 aa)
          score_image score_image   0.934
COL3A1
collagen, type III, alpha 1 (1466 aa)
      score_image   score_image score_image score_image 0.930
COL5A2
collagen, type V, alpha 2 (1499 aa)
      score_image   score_image score_image score_image 0.930
COL17A1
collagen, type XVII, alpha 1; May play a role in the integrity of hemidesmosome and the attachment of basal keratinocytes to the underlying basement membrane (1497 aa)
          score_image score_image   0.926
COL1A2
collagen, type I, alpha 2 (1366 aa)
      score_image   score_image score_image score_image 0.926
COL1A1
collagen, type I, alpha 1 (1464 aa)
      score_image   score_image score_image score_image 0.923
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man
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