TMEM79 protein (Homo sapiens) - STRING network view

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TMEM79

transmembrane protein 79 (394 aa)

Predicted Functional Partners:

TMPRSS4

0.778

PLN

0.692

TNMD

0.594

TEX264

0.594

SERP1

0.594

RPRM

0.531

PNPLA7

0.480

SMG5

0.472

ENSG00000261832

0.456

GPR119

0.453

Your Current Organism:

Homo sapiens

NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSG00000261832	TMEM79	ENSP00000454253	ENSP00000295694	Battenin; CLN3 protein; Uncharacterized protein	transmembrane protein 79	0.456
GPR119	TMEM79	ENSP00000276218	ENSP00000295694	G protein-coupled receptor 119; Receptor for the endogenous fatty-acid ethanolamide oleoylethanolamide (OEA) and lysophosphatidylcholine (LPC). Functions as a glucose-dependent insulinotropic receptor. The activity of this receptor is mediated by G proteins which activate adenylate cyclase. Seems to act through a G(s) mediated pathway	transmembrane protein 79	0.453
PLN	TMEM79	ENSP00000350132	ENSP00000295694	phospholamban; Phospholamban has been postulated to regulate the activity of the calcium pump of cardiac sarcoplasmic reticulum	transmembrane protein 79	0.692
PNPLA7	TMEM79	ENSP00000384610	ENSP00000295694	patatin-like phospholipase domain containing 7	transmembrane protein 79	0.480
RPRM	TMEM79	ENSP00000314946	ENSP00000295694	reprimo, TP53 dependent G2 arrest mediator candidate; May be involved in the regulation of p53-dependent G2 arrest of the cell cycle. Seems to induce cell cycle arrest by inhibiting CDK1 activity and nuclear translocation of the CDC2 cyclin B1 complex (By similarity)	transmembrane protein 79	0.531
SERP1	TMEM79	ENSP00000239944	ENSP00000295694	stress-associated endoplasmic reticulum protein 1; Interacts with target proteins during their translocation into the lumen of the endoplasmic reticulum. Protects unfolded target proteins against degradation during ER stress. May facilitate glycosylation of target proteins after termination of ER stress. May modulate the use of N-glycosylation sites on target proteins (By similarity)	transmembrane protein 79	0.594
SMG5	TMEM79	ENSP00000355261	ENSP00000295694	smg-5 homolog, nonsense mediated mRNA decay factor (C. elegans); Plays a role in nonsense-mediated mRNA decay. Does not have RNase activity by itself. Promotes dephosphorylation of UPF1. Together with SMG7 is thought to provide a link to the mRNA degradation machinery involving exonucleolytic pathways, and to serve as an adapter for UPF1 to protein phosphatase 2A (PP2A), thereby triggering UPF1 dephosphorylation. Necessary for TERT activity	transmembrane protein 79	0.472
TEX264	TMEM79	ENSP00000340969	ENSP00000295694	testis expressed 264	transmembrane protein 79	0.594
TMEM79	ENSG00000261832	ENSP00000295694	ENSP00000454253	transmembrane protein 79	Battenin; CLN3 protein; Uncharacterized protein	0.456
TMEM79	GPR119	ENSP00000295694	ENSP00000276218	transmembrane protein 79	G protein-coupled receptor 119; Receptor for the endogenous fatty-acid ethanolamide oleoylethanolamide (OEA) and lysophosphatidylcholine (LPC). Functions as a glucose-dependent insulinotropic receptor. The activity of this receptor is mediated by G proteins which activate adenylate cyclase. Seems to act through a G(s) mediated pathway	0.453
TMEM79	PLN	ENSP00000295694	ENSP00000350132	transmembrane protein 79	phospholamban; Phospholamban has been postulated to regulate the activity of the calcium pump of cardiac sarcoplasmic reticulum	0.692
TMEM79	PNPLA7	ENSP00000295694	ENSP00000384610	transmembrane protein 79	patatin-like phospholipase domain containing 7	0.480
TMEM79	RPRM	ENSP00000295694	ENSP00000314946	transmembrane protein 79	reprimo, TP53 dependent G2 arrest mediator candidate; May be involved in the regulation of p53-dependent G2 arrest of the cell cycle. Seems to induce cell cycle arrest by inhibiting CDK1 activity and nuclear translocation of the CDC2 cyclin B1 complex (By similarity)	0.531
TMEM79	SERP1	ENSP00000295694	ENSP00000239944	transmembrane protein 79	stress-associated endoplasmic reticulum protein 1; Interacts with target proteins during their translocation into the lumen of the endoplasmic reticulum. Protects unfolded target proteins against degradation during ER stress. May facilitate glycosylation of target proteins after termination of ER stress. May modulate the use of N-glycosylation sites on target proteins (By similarity)	0.594
TMEM79	SMG5	ENSP00000295694	ENSP00000355261	transmembrane protein 79	smg-5 homolog, nonsense mediated mRNA decay factor (C. elegans); Plays a role in nonsense-mediated mRNA decay. Does not have RNase activity by itself. Promotes dephosphorylation of UPF1. Together with SMG7 is thought to provide a link to the mRNA degradation machinery involving exonucleolytic pathways, and to serve as an adapter for UPF1 to protein phosphatase 2A (PP2A), thereby triggering UPF1 dephosphorylation. Necessary for TERT activity	0.472
TMEM79	TEX264	ENSP00000295694	ENSP00000340969	transmembrane protein 79	testis expressed 264	0.594
TMEM79	TMPRSS4	ENSP00000295694	ENSP00000416037	transmembrane protein 79	transmembrane protease, serine 4; Probable protease. Seems to be capable of activating ENaC (By similarity)	0.778
TMEM79	TNMD	ENSP00000295694	ENSP00000362122	transmembrane protein 79	tenomodulin; May be an angiogenesis inhibitor	0.594
TMPRSS4	TMEM79	ENSP00000416037	ENSP00000295694	transmembrane protease, serine 4; Probable protease. Seems to be capable of activating ENaC (By similarity)	transmembrane protein 79	0.778
TNMD	TMEM79	ENSP00000362122	ENSP00000295694	tenomodulin; May be an angiogenesis inhibitor	transmembrane protein 79	0.594

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