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STRINGSTRING
ENSG00000260914 ENSG00000260914 OSBPL9 OSBPL9 VAPB VAPB VPS4A VPS4A OSBPL11 OSBPL11 VPS4B VPS4B UBC UBC WDR44 WDR44 TRIP10 TRIP10 PLEK PLEK AP1G1 AP1G1
"OSBPL11" - oxysterol binding protein-like 11 in Homo sapiens
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Size
small protein node
small nodes:
protein of unknown 3D structure
large protein node
large nodes:
some 3D structure is known or predicted
Node Color
colored protein node
colored nodes:
query proteins and first shell of interactors
non-colored protein node
white nodes:
second shell of interactors
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
database edge
from curated databases
experiment edge
experimentally determined
Predicted Interactions
neighborhood edge
gene neighborhood
fusion edge
gene fusions
cooccurrence edge
gene co-occurrence
Others
textmining edge
textmining
coexpression edge
co-expression
homology edge
protein homology
Your Input:
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Gene Fusion
Cooccurence
Coexpression
Experiments
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Textmining
[Homology]
Score
OSBPL11oxysterol binding protein-like 11 (747 aa)    
Predicted Functional Partners:
UBC
ubiquitin C (685 aa)
        score_image       0.861
OSBPL9
oxysterol binding protein-like 9 (746 aa)
        score_image   score_image score_image 0.758
PLEK
pleckstrin; Major protein kinase C substrate of platelets (350 aa)
            score_image   0.560
AP1G1
adaptor-related protein complex 1, gamma 1 subunit; Subunit of clathrin-associated adaptor protein complex 1 that plays a role in protein sorting in the late-Golgi/trans-Golgi network (TGN) and/or endosomes. The AP complexes mediate both the recruitment of clathrin to membranes and the recognition of sorting signals within the cytosolic tails of transmembrane cargo molecules (825 aa)
        score_image       0.538
TRIP10
thyroid hormone receptor interactor 10 (545 aa)
        score_image       0.538
WDR44
WD repeat domain 44 (913 aa)
        score_image       0.538
VAPB
VAMP (vesicle-associated membrane protein)-associated protein B and C; Participates in the endoplasmic reticulum unfolded protein response (UPR) by inducing ERN1/IRE1 activity. Involved in cellular calcium homeostasis regulation (243 aa)
        score_image   score_image   0.534
ENSG00000260914
Uncharacterized protein (288 aa)
        score_image   score_image   0.523
VPS4A
vacuolar protein sorting 4 homolog A (S. cerevisiae); Involved in late steps of the endosomal multivesicular bodies (MVB) pathway. Recognizes membrane-associated ESCRT-III assemblies and catalyzes their disassembly, possibly in combination with membrane fission. Redistributes the ESCRT-III components to the cytoplasm for further rounds of MVB sorting. MVBs contain intraluminal vesicles (ILVs) that are generated by invagination and scission from the limiting membrane of the endosome and mostly are delivered to lysosomes enabling degradation of membrane proteins, such as stimulated growt [...] (437 aa)
        score_image   score_image   0.523
VPS4B
vacuolar protein sorting 4 homolog B (S. cerevisiae); Involved in late steps of the endosomal multivesicular bodies (MVB) pathway. Recognizes membrane-associated ESCRT-III assemblies and catalyzes their disassembly, possibly in combination with membrane fission. Redistributes the ESCRT-III components to the cytoplasm for further rounds of MVB sorting. MVBs contain intraluminal vesicles (ILVs) that are generated by invagination and scission from the limiting membrane of the endosome and mostly are delivered to lysosomes enabling degradation of membrane proteins, such as stimulated growt [...] (444 aa)
        score_image   score_image   0.523
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man
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