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STRINGSTRING
CCDC37 CCDC37 PODXL2 PODXL2 TMCC1 TMCC1 MCM7 MCM7 BCAT2 BCAT2 KLF15 KLF15 FAM132A FAM132A CTGF CTGF MEF2A MEF2A INS INS SLC2A4 SLC2A4
"KLF15" - Kruppel-like factor 15 in Homo sapiens
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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protein of unknown 3D structure
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some 3D structure is known or predicted
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query proteins and first shell of interactors
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white nodes:
second shell of interactors
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Known Interactions
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from curated databases
experiment edge
experimentally determined
Predicted Interactions
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gene neighborhood
fusion edge
gene fusions
cooccurrence edge
gene co-occurrence
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textmining edge
textmining
coexpression edge
co-expression
homology edge
protein homology
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[Homology]
Score
KLF15Kruppel-like factor 15; Transcriptional activator. Binds to the GA element of the CLCNKA promoter (416 aa)    
Predicted Functional Partners:
SLC2A4
solute carrier family 2 (facilitated glucose transporter), member 4; Insulin-regulated facilitative glucose transporter (509 aa)
            score_image   0.926
BCAT2
branched chain amino-acid transaminase 2, mitochondrial; Catalyzes the first reaction in the catabolism of the essential branched chain amino acids leucine, isoleucine, and valine. May also function as a transporter of branched chain alpha-keto acids (392 aa)
            score_image   0.918
MEF2A
myocyte enhancer factor 2A (499 aa)
        score_image   score_image   0.886
INS
insulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver (By similarity) (110 aa)
            score_image   0.866
CTGF
connective tissue growth factor; Major connective tissue mitoattractant secreted by vascular endothelial cells. Promotes proliferation and differentiation of chondrocytes. Mediates heparin- and divalent cation-dependent cell adhesion in many cell types including fibroblasts, myofibroblasts, endothelial and epithelial cells. Enhances fibroblast growth factor-induced DNA synthesis (349 aa)
            score_image   0.841
FAM132A
family with sequence similarity 132, member A (302 aa)
            score_image   0.826
MCM7
minichromosome maintenance complex component 7; Acts as component of the MCM2-7 complex (MCM complex) which is the putative replicative helicase essential for ’once per cell cycle’ DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the MCM2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute dif [...] (719 aa)
      score_image     score_image   0.824
TMCC1
transmembrane and coiled-coil domain family 1 (653 aa)
            score_image   0.813
PODXL2
podocalyxin-like 2; Acts as a ligand for vascular selectins. Mediates rapid rolling of leukocytes over vascular surfaces through high affinity divalent cation-dependent interactions with E-, P- and L- selectins (605 aa)
            score_image   0.813
CCDC37
coiled-coil domain containing 37 (611 aa)
            score_image   0.813
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man
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