node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
CEP97 | POC1A | ENSP00000342510 | ENSP00000296484 | centrosomal protein 97kDa; Acts as a key negative regulator of ciliogenesis in collaboration with CCP110 by capping the mother centriole thereby preventing cilia formation. Required for recruitment of CCP110 to the centrosome | POC1 centriolar protein homolog A (Chlamydomonas); Involved in early steps of centriole duplication, as well as in the later steps of centriole length control. Required for ciliogenesis | 0.604 |
FGFR1OP2 | POC1A | ENSP00000229395 | ENSP00000296484 | FGFR1 oncogene partner 2; May be involved in wound healing pathway (By similarity) | POC1 centriolar protein homolog A (Chlamydomonas); Involved in early steps of centriole duplication, as well as in the later steps of centriole length control. Required for ciliogenesis | 0.644 |
FTH1 | GLRA1 | ENSP00000273550 | ENSP00000411593 | ferritin, heavy polypeptide 1; Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Has ferroxidase activity. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation. Also plays a role in delivery of iron to cells. Mediates iron uptake in capsule cells of the developing kidney (By similarity) | glycine receptor, alpha 1; The glycine receptor is a neurotransmitter-gated ion channel. Binding of glycine to its receptor increases the chloride conductance and thus produces hyperpolarization (inhibition of neuronal firing) | 0.645 |
FTH1 | HADH | ENSP00000273550 | ENSP00000385638 | ferritin, heavy polypeptide 1; Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Has ferroxidase activity. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation. Also plays a role in delivery of iron to cells. Mediates iron uptake in capsule cells of the developing kidney (By similarity) | hydroxyacyl-CoA dehydrogenase; Plays an essential role in the mitochondrial beta- oxidation of short chain fatty acids. Exerts it highest activity toward 3-hydroxybutyryl-CoA | 0.827 |
FTH1 | OMP | ENSP00000273550 | ENSP00000436376 | ferritin, heavy polypeptide 1; Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Has ferroxidase activity. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation. Also plays a role in delivery of iron to cells. Mediates iron uptake in capsule cells of the developing kidney (By similarity) | olfactory marker protein; May act as a modulator of the olfactory signal- transduction cascade | 0.740 |
FTH1 | POC1A | ENSP00000273550 | ENSP00000296484 | ferritin, heavy polypeptide 1; Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Has ferroxidase activity. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation. Also plays a role in delivery of iron to cells. Mediates iron uptake in capsule cells of the developing kidney (By similarity) | POC1 centriolar protein homolog A (Chlamydomonas); Involved in early steps of centriole duplication, as well as in the later steps of centriole length control. Required for ciliogenesis | 0.654 |
FTH1 | RRBP1 | ENSP00000273550 | ENSP00000354045 | ferritin, heavy polypeptide 1; Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Has ferroxidase activity. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation. Also plays a role in delivery of iron to cells. Mediates iron uptake in capsule cells of the developing kidney (By similarity) | ribosome binding protein 1 homolog 180kDa (dog) | 0.755 |
GLRA1 | FTH1 | ENSP00000411593 | ENSP00000273550 | glycine receptor, alpha 1; The glycine receptor is a neurotransmitter-gated ion channel. Binding of glycine to its receptor increases the chloride conductance and thus produces hyperpolarization (inhibition of neuronal firing) | ferritin, heavy polypeptide 1; Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Has ferroxidase activity. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation. Also plays a role in delivery of iron to cells. Mediates iron uptake in capsule cells of the developing kidney (By similarity) | 0.645 |
GLRA1 | HADH | ENSP00000411593 | ENSP00000385638 | glycine receptor, alpha 1; The glycine receptor is a neurotransmitter-gated ion channel. Binding of glycine to its receptor increases the chloride conductance and thus produces hyperpolarization (inhibition of neuronal firing) | hydroxyacyl-CoA dehydrogenase; Plays an essential role in the mitochondrial beta- oxidation of short chain fatty acids. Exerts it highest activity toward 3-hydroxybutyryl-CoA | 0.499 |
GLRA1 | OMP | ENSP00000411593 | ENSP00000436376 | glycine receptor, alpha 1; The glycine receptor is a neurotransmitter-gated ion channel. Binding of glycine to its receptor increases the chloride conductance and thus produces hyperpolarization (inhibition of neuronal firing) | olfactory marker protein; May act as a modulator of the olfactory signal- transduction cascade | 0.418 |
GLRA1 | POC1A | ENSP00000411593 | ENSP00000296484 | glycine receptor, alpha 1; The glycine receptor is a neurotransmitter-gated ion channel. Binding of glycine to its receptor increases the chloride conductance and thus produces hyperpolarization (inhibition of neuronal firing) | POC1 centriolar protein homolog A (Chlamydomonas); Involved in early steps of centriole duplication, as well as in the later steps of centriole length control. Required for ciliogenesis | 0.560 |
GLRA1 | RRBP1 | ENSP00000411593 | ENSP00000354045 | glycine receptor, alpha 1; The glycine receptor is a neurotransmitter-gated ion channel. Binding of glycine to its receptor increases the chloride conductance and thus produces hyperpolarization (inhibition of neuronal firing) | ribosome binding protein 1 homolog 180kDa (dog) | 0.479 |
HADH | FTH1 | ENSP00000385638 | ENSP00000273550 | hydroxyacyl-CoA dehydrogenase; Plays an essential role in the mitochondrial beta- oxidation of short chain fatty acids. Exerts it highest activity toward 3-hydroxybutyryl-CoA | ferritin, heavy polypeptide 1; Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Has ferroxidase activity. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation. Also plays a role in delivery of iron to cells. Mediates iron uptake in capsule cells of the developing kidney (By similarity) | 0.827 |
HADH | GLRA1 | ENSP00000385638 | ENSP00000411593 | hydroxyacyl-CoA dehydrogenase; Plays an essential role in the mitochondrial beta- oxidation of short chain fatty acids. Exerts it highest activity toward 3-hydroxybutyryl-CoA | glycine receptor, alpha 1; The glycine receptor is a neurotransmitter-gated ion channel. Binding of glycine to its receptor increases the chloride conductance and thus produces hyperpolarization (inhibition of neuronal firing) | 0.499 |
HADH | OMP | ENSP00000385638 | ENSP00000436376 | hydroxyacyl-CoA dehydrogenase; Plays an essential role in the mitochondrial beta- oxidation of short chain fatty acids. Exerts it highest activity toward 3-hydroxybutyryl-CoA | olfactory marker protein; May act as a modulator of the olfactory signal- transduction cascade | 0.648 |
HADH | POC1A | ENSP00000385638 | ENSP00000296484 | hydroxyacyl-CoA dehydrogenase; Plays an essential role in the mitochondrial beta- oxidation of short chain fatty acids. Exerts it highest activity toward 3-hydroxybutyryl-CoA | POC1 centriolar protein homolog A (Chlamydomonas); Involved in early steps of centriole duplication, as well as in the later steps of centriole length control. Required for ciliogenesis | 0.563 |
HADH | RRBP1 | ENSP00000385638 | ENSP00000354045 | hydroxyacyl-CoA dehydrogenase; Plays an essential role in the mitochondrial beta- oxidation of short chain fatty acids. Exerts it highest activity toward 3-hydroxybutyryl-CoA | ribosome binding protein 1 homolog 180kDa (dog) | 0.638 |
OMP | FTH1 | ENSP00000436376 | ENSP00000273550 | olfactory marker protein; May act as a modulator of the olfactory signal- transduction cascade | ferritin, heavy polypeptide 1; Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Has ferroxidase activity. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation. Also plays a role in delivery of iron to cells. Mediates iron uptake in capsule cells of the developing kidney (By similarity) | 0.740 |
OMP | GLRA1 | ENSP00000436376 | ENSP00000411593 | olfactory marker protein; May act as a modulator of the olfactory signal- transduction cascade | glycine receptor, alpha 1; The glycine receptor is a neurotransmitter-gated ion channel. Binding of glycine to its receptor increases the chloride conductance and thus produces hyperpolarization (inhibition of neuronal firing) | 0.418 |
OMP | HADH | ENSP00000436376 | ENSP00000385638 | olfactory marker protein; May act as a modulator of the olfactory signal- transduction cascade | hydroxyacyl-CoA dehydrogenase; Plays an essential role in the mitochondrial beta- oxidation of short chain fatty acids. Exerts it highest activity toward 3-hydroxybutyryl-CoA | 0.648 |