node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ETS1 | LMO2 | ENSP00000376436 | ENSP00000257818 | v-ets erythroblastosis virus E26 oncogene homolog 1 (avian); Transcription factor. Directly controls the expression of cytokine and chemokine genes in a wide variety of different cellular contexts. May control the differentiation, survival and proliferation of lymphoid cells. May also regulate angiogenesis through regulation of expression of genes controlling endothelial cell migration and invasion | LIM domain only 2 (rhombotin-like 1); Acts with TAL1/SCL to regulate red blood cell development. Also acts with LDB1 to maintain erythroid precursors in an immature state | 0.421 |
ETS1 | MEIS1 | ENSP00000376436 | ENSP00000272369 | v-ets erythroblastosis virus E26 oncogene homolog 1 (avian); Transcription factor. Directly controls the expression of cytokine and chemokine genes in a wide variety of different cellular contexts. May control the differentiation, survival and proliferation of lymphoid cells. May also regulate angiogenesis through regulation of expression of genes controlling endothelial cell migration and invasion | Meis homeobox 1; Acts as a transcriptional regulator of PAX6. Acts as a transcriptional activator of PF4 in complex with PBX1 or PBX2. Required for hematopoiesis, megakaryocyte lineage development and vascular patterning. May function as a cofactor for HOXA7 and HOXA9 in the induction of myeloid leukemias | 0.711 |
ETS1 | TAL1 | ENSP00000376436 | ENSP00000294339 | v-ets erythroblastosis virus E26 oncogene homolog 1 (avian); Transcription factor. Directly controls the expression of cytokine and chemokine genes in a wide variety of different cellular contexts. May control the differentiation, survival and proliferation of lymphoid cells. May also regulate angiogenesis through regulation of expression of genes controlling endothelial cell migration and invasion | T-cell acute lymphocytic leukemia 1; Implicated in the genesis of hemopoietic malignancies. It may play an important role in hemopoietic differentiation. Serves as a positive regulator of erythroid differentiation (By similarity) | 0.709 |
ETS1 | TLX3 | ENSP00000376436 | ENSP00000296921 | v-ets erythroblastosis virus E26 oncogene homolog 1 (avian); Transcription factor. Directly controls the expression of cytokine and chemokine genes in a wide variety of different cellular contexts. May control the differentiation, survival and proliferation of lymphoid cells. May also regulate angiogenesis through regulation of expression of genes controlling endothelial cell migration and invasion | T-cell leukemia homeobox 3 | 0.641 |
LMO1 | LYL1 | ENSP00000338207 | ENSP00000264824 | LIM domain only 1 (rhombotin 1); May be involved in gene regulation within neural lineage cells potentially by direct DNA binding or by binding to other transcription factors | lymphoblastic leukemia derived sequence 1 | 0.880 |
LMO1 | NUP214 | ENSP00000338207 | ENSP00000352400 | LIM domain only 1 (rhombotin 1); May be involved in gene regulation within neural lineage cells potentially by direct DNA binding or by binding to other transcription factors | nucleoporin 214kDa; May serve as a docking site in the receptor-mediated import of substrates across the nuclear pore complex | 0.400 |
LMO1 | RANBP17 | ENSP00000338207 | ENSP00000427975 | LIM domain only 1 (rhombotin 1); May be involved in gene regulation within neural lineage cells potentially by direct DNA binding or by binding to other transcription factors | RAN binding protein 17; May function as a nuclear transport receptor (By similarity) | 0.564 |
LMO1 | TAL1 | ENSP00000338207 | ENSP00000294339 | LIM domain only 1 (rhombotin 1); May be involved in gene regulation within neural lineage cells potentially by direct DNA binding or by binding to other transcription factors | T-cell acute lymphocytic leukemia 1; Implicated in the genesis of hemopoietic malignancies. It may play an important role in hemopoietic differentiation. Serves as a positive regulator of erythroid differentiation (By similarity) | 0.950 |
LMO1 | TLX3 | ENSP00000338207 | ENSP00000296921 | LIM domain only 1 (rhombotin 1); May be involved in gene regulation within neural lineage cells potentially by direct DNA binding or by binding to other transcription factors | T-cell leukemia homeobox 3 | 0.680 |
LMO2 | ETS1 | ENSP00000257818 | ENSP00000376436 | LIM domain only 2 (rhombotin-like 1); Acts with TAL1/SCL to regulate red blood cell development. Also acts with LDB1 to maintain erythroid precursors in an immature state | v-ets erythroblastosis virus E26 oncogene homolog 1 (avian); Transcription factor. Directly controls the expression of cytokine and chemokine genes in a wide variety of different cellular contexts. May control the differentiation, survival and proliferation of lymphoid cells. May also regulate angiogenesis through regulation of expression of genes controlling endothelial cell migration and invasion | 0.421 |
LMO2 | LYL1 | ENSP00000257818 | ENSP00000264824 | LIM domain only 2 (rhombotin-like 1); Acts with TAL1/SCL to regulate red blood cell development. Also acts with LDB1 to maintain erythroid precursors in an immature state | lymphoblastic leukemia derived sequence 1 | 0.894 |
LMO2 | MEIS1 | ENSP00000257818 | ENSP00000272369 | LIM domain only 2 (rhombotin-like 1); Acts with TAL1/SCL to regulate red blood cell development. Also acts with LDB1 to maintain erythroid precursors in an immature state | Meis homeobox 1; Acts as a transcriptional regulator of PAX6. Acts as a transcriptional activator of PF4 in complex with PBX1 or PBX2. Required for hematopoiesis, megakaryocyte lineage development and vascular patterning. May function as a cofactor for HOXA7 and HOXA9 in the induction of myeloid leukemias | 0.497 |
LMO2 | RANBP17 | ENSP00000257818 | ENSP00000427975 | LIM domain only 2 (rhombotin-like 1); Acts with TAL1/SCL to regulate red blood cell development. Also acts with LDB1 to maintain erythroid precursors in an immature state | RAN binding protein 17; May function as a nuclear transport receptor (By similarity) | 0.438 |
LMO2 | TAL1 | ENSP00000257818 | ENSP00000294339 | LIM domain only 2 (rhombotin-like 1); Acts with TAL1/SCL to regulate red blood cell development. Also acts with LDB1 to maintain erythroid precursors in an immature state | T-cell acute lymphocytic leukemia 1; Implicated in the genesis of hemopoietic malignancies. It may play an important role in hemopoietic differentiation. Serves as a positive regulator of erythroid differentiation (By similarity) | 0.999 |
LMO2 | TLX3 | ENSP00000257818 | ENSP00000296921 | LIM domain only 2 (rhombotin-like 1); Acts with TAL1/SCL to regulate red blood cell development. Also acts with LDB1 to maintain erythroid precursors in an immature state | T-cell leukemia homeobox 3 | 0.654 |
LYL1 | LMO1 | ENSP00000264824 | ENSP00000338207 | lymphoblastic leukemia derived sequence 1 | LIM domain only 1 (rhombotin 1); May be involved in gene regulation within neural lineage cells potentially by direct DNA binding or by binding to other transcription factors | 0.880 |
LYL1 | LMO2 | ENSP00000264824 | ENSP00000257818 | lymphoblastic leukemia derived sequence 1 | LIM domain only 2 (rhombotin-like 1); Acts with TAL1/SCL to regulate red blood cell development. Also acts with LDB1 to maintain erythroid precursors in an immature state | 0.894 |
LYL1 | RANBP17 | ENSP00000264824 | ENSP00000427975 | lymphoblastic leukemia derived sequence 1 | RAN binding protein 17; May function as a nuclear transport receptor (By similarity) | 0.657 |
LYL1 | TAL1 | ENSP00000264824 | ENSP00000294339 | lymphoblastic leukemia derived sequence 1 | T-cell acute lymphocytic leukemia 1; Implicated in the genesis of hemopoietic malignancies. It may play an important role in hemopoietic differentiation. Serves as a positive regulator of erythroid differentiation (By similarity) | 0.633 |
LYL1 | TLX3 | ENSP00000264824 | ENSP00000296921 | lymphoblastic leukemia derived sequence 1 | T-cell leukemia homeobox 3 | 0.674 |