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STRINGSTRING
BST2 BST2 RNF122 RNF122 PRLR PRLR AGTRAP AGTRAP CAMLG CAMLG LCK LCK EGFR EGFR TMUB1 TMUB1 PKHD1 PKHD1 TNFRSF13B TNFRSF13B TNFSF13B TNFSF13B
"CAMLG" - calcium modulating ligand in Homo sapiens
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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protein of unknown 3D structure
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second shell of interactors
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Predicted Interactions
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CAMLGcalcium modulating ligand; Likely involved in the mobilization of calcium as a result of the TCR/CD3 complex interaction. Binds to cyclophilin B (296 aa)    
Predicted Functional Partners:
AGTRAP
angiotensin II receptor-associated protein; Appears to be a negative regulator of type-1 angiotensin II receptor-mediated signaling by regulating receptor internalisation as well as mechanism of receptor desensitization such as phosphorylation. Induces also a decrease in cell proliferation and angiotensin II-stimulated transcriptional activity (159 aa)
            score_image   0.949
TNFRSF13B
tumor necrosis factor receptor superfamily, member 13B; Receptor for TNFSF13/APRIL and TNFSF13B/TALL1/BAFF/BLYS that binds both ligands with similar high affinity. Mediates calcineurin-dependent activation of NF-AT, as well as activation of NF-kappa-B and AP-1. Involved in the stimulation of B- and T- cell function and the regulation of humoral immunity (293 aa)
        score_image   score_image   0.941
TMUB1
transmembrane and ubiquitin-like domain containing 1; May contribute to the regulation of translation during cell-cycle progression. May contribute to the regulation of cell proliferation (By similarity) (246 aa)
        score_image   score_image   0.941
PKHD1
polycystic kidney and hepatic disease 1 (autosomal recessive); May be required for correct bipolar cell division through the regulation of centrosome duplication and mitotic spindle assembly. May be a receptor protein that acts in collecting-duct and biliary differentiation (4074 aa)
        score_image   score_image   0.926
RNF122
ring finger protein 122; May induce necrosis and apoptosis. May play a role in cell viability (155 aa)
        score_image   score_image   0.924
LCK
lymphocyte-specific protein tyrosine kinase (509 aa)
            score_image   0.845
PRLR
prolactin receptor (622 aa)
            score_image   0.810
EGFR
epidermal growth factor receptor (1210 aa)
        score_image   score_image   0.795
TNFSF13B
tumor necrosis factor (ligand) superfamily, member 13b; Cytokine that binds to TNFRSF13B/TACI and TNFRSF17/BCMA. TNFSF13/APRIL binds to the same 2 receptors. Together, they form a 2 ligands -2 receptors pathway involved in the stimulation of B- and T-cell function and the regulation of humoral immunity. A third B-cell specific BAFF-receptor (BAFFR/BR3) promotes the survival of mature B-cells and the B-cell response (285 aa)
            score_image   0.769
BST2
bone marrow stromal cell antigen 2; IFN-induced antiviral host restriction factor which efficiently blocks the release of diverse mammalian enveloped viruses by directly tethering nascent virions to the membranes of infected cells. Acts as a direct physical tether, holding virions to the cell membrane and linking virions to each other. The tethered virions can be internalized by endocytosis and subsequently degraded or they can remain on the cell surface. In either case, their spread as cell-free virions is restricted. Its target viruses belong to diverse families, including retrovirid [...] (180 aa)
            score_image   0.689
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man
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