node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ANXA13 | CSMD3 | ENSP00000262219 | ENSP00000297405 | annexin A13 | CUB and Sushi multiple domains 3 | 0.814 |
ANXA13 | EXT1 | ENSP00000262219 | ENSP00000367446 | annexin A13 | exostosin 1; Glycosyltransferase required for the biosynthesis of heparan-sulfate. The EXT1/EXT2 complex possesses substantially higher glycosyltransferase activity than EXT1 or EXT2 alone. Appears to be a tumor suppressor | 0.744 |
ANXA13 | FTSJD1 | ENSP00000262219 | ENSP00000337512 | annexin A13 | FtsJ methyltransferase domain containing 1 | 0.813 |
ANXA13 | TRPS1 | ENSP00000262219 | ENSP00000379065 | annexin A13 | trichorhinophalangeal syndrome I; Transcriptional repressor. Binds specifically to GATA sequences and represses expression of GATA-regulated genes at selected sites and stages in vertebrate development. Regulates chondrocyte proliferation and differentiation. Executes multiple functions in proliferating chondrocytes, expanding the region of distal chondrocytes, activating proliferation in columnar cells and supporting the differentiation of columnar into hypertrophic chondrocytes | 0.743 |
CNTNAP2 | CSMD3 | ENSP00000354778 | ENSP00000297405 | contactin associated protein-like 2; May play a role in the formation of functional distinct domains critical for saltatory conduction of nerve impulses in myelinated nerve fibers. Seems to demarcate the juxtaparanodal region of the axo-glial junction | CUB and Sushi multiple domains 3 | 0.473 |
CSMD3 | ANXA13 | ENSP00000297405 | ENSP00000262219 | CUB and Sushi multiple domains 3 | annexin A13 | 0.814 |
CSMD3 | CNTNAP2 | ENSP00000297405 | ENSP00000354778 | CUB and Sushi multiple domains 3 | contactin associated protein-like 2; May play a role in the formation of functional distinct domains critical for saltatory conduction of nerve impulses in myelinated nerve fibers. Seems to demarcate the juxtaparanodal region of the axo-glial junction | 0.473 |
CSMD3 | EXT1 | ENSP00000297405 | ENSP00000367446 | CUB and Sushi multiple domains 3 | exostosin 1; Glycosyltransferase required for the biosynthesis of heparan-sulfate. The EXT1/EXT2 complex possesses substantially higher glycosyltransferase activity than EXT1 or EXT2 alone. Appears to be a tumor suppressor | 0.660 |
CSMD3 | FTSJD1 | ENSP00000297405 | ENSP00000337512 | CUB and Sushi multiple domains 3 | FtsJ methyltransferase domain containing 1 | 0.757 |
CSMD3 | GDF6 | ENSP00000297405 | ENSP00000287020 | CUB and Sushi multiple domains 3 | growth differentiation factor 6; Required for normal formation of bones and joints in the limbs, skull, and axial skeleton. Plays a key role in establishing boundaries between skeletal elements during development (By similarity) | 0.607 |
CSMD3 | NUDT8 | ENSP00000297405 | ENSP00000301490 | CUB and Sushi multiple domains 3 | nudix (nucleoside diphosphate linked moiety X)-type motif 8; Probably mediates the hydrolysis of some nucleoside diphosphate derivatives (By similarity) | 0.472 |
CSMD3 | PER1 | ENSP00000297405 | ENSP00000314420 | CUB and Sushi multiple domains 3 | period homolog 1 (Drosophila); Component of the circadian clock mechanism which is essential for generating circadian rhythms. Negative element in the circadian transcriptional loop. Influences clock function by interacting with other circadian regulatory proteins and transporting them to the nucleus. Negatively regulates CLOCK|NPAS2-BMAL1|BMAL2-induced transactivation. Can bind heme (By similarity) | 0.525 |
CSMD3 | TRPS1 | ENSP00000297405 | ENSP00000379065 | CUB and Sushi multiple domains 3 | trichorhinophalangeal syndrome I; Transcriptional repressor. Binds specifically to GATA sequences and represses expression of GATA-regulated genes at selected sites and stages in vertebrate development. Regulates chondrocyte proliferation and differentiation. Executes multiple functions in proliferating chondrocytes, expanding the region of distal chondrocytes, activating proliferation in columnar cells and supporting the differentiation of columnar into hypertrophic chondrocytes | 0.757 |
CSMD3 | TXNDC2 | ENSP00000297405 | ENSP00000304908 | CUB and Sushi multiple domains 3 | thioredoxin domain containing 2 (spermatozoa); Probably plays a regulatory role in sperm development. May participate in regulation of fibrous sheath (FS) assembly by supporting the formation of disulfide bonds during sperm tail morphogenesis. May also be required to rectify incorrect disulfide pairing and generate suitable pairs between the FS constituents. Can reduce disulfide bonds in vitro in the presence of NADP and thioredoxin reductase | 0.491 |
CSMD3 | UBC | ENSP00000297405 | ENSP00000344818 | CUB and Sushi multiple domains 3 | ubiquitin C | 0.486 |
EXT1 | ANXA13 | ENSP00000367446 | ENSP00000262219 | exostosin 1; Glycosyltransferase required for the biosynthesis of heparan-sulfate. The EXT1/EXT2 complex possesses substantially higher glycosyltransferase activity than EXT1 or EXT2 alone. Appears to be a tumor suppressor | annexin A13 | 0.744 |
EXT1 | CSMD3 | ENSP00000367446 | ENSP00000297405 | exostosin 1; Glycosyltransferase required for the biosynthesis of heparan-sulfate. The EXT1/EXT2 complex possesses substantially higher glycosyltransferase activity than EXT1 or EXT2 alone. Appears to be a tumor suppressor | CUB and Sushi multiple domains 3 | 0.660 |
EXT1 | FTSJD1 | ENSP00000367446 | ENSP00000337512 | exostosin 1; Glycosyltransferase required for the biosynthesis of heparan-sulfate. The EXT1/EXT2 complex possesses substantially higher glycosyltransferase activity than EXT1 or EXT2 alone. Appears to be a tumor suppressor | FtsJ methyltransferase domain containing 1 | 0.658 |
EXT1 | TRPS1 | ENSP00000367446 | ENSP00000379065 | exostosin 1; Glycosyltransferase required for the biosynthesis of heparan-sulfate. The EXT1/EXT2 complex possesses substantially higher glycosyltransferase activity than EXT1 or EXT2 alone. Appears to be a tumor suppressor | trichorhinophalangeal syndrome I; Transcriptional repressor. Binds specifically to GATA sequences and represses expression of GATA-regulated genes at selected sites and stages in vertebrate development. Regulates chondrocyte proliferation and differentiation. Executes multiple functions in proliferating chondrocytes, expanding the region of distal chondrocytes, activating proliferation in columnar cells and supporting the differentiation of columnar into hypertrophic chondrocytes | 0.812 |
FTSJD1 | ANXA13 | ENSP00000337512 | ENSP00000262219 | FtsJ methyltransferase domain containing 1 | annexin A13 | 0.813 |