Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Size
small nodes:
protein of unknown 3D structure
protein of unknown 3D structure
large nodes:
some 3D structure is known or predicted
some 3D structure is known or predicted
Node Color
colored nodes:
query proteins and first shell of interactors
query proteins and first shell of interactors
white nodes:
second shell of interactors
second shell of interactors
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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Your Input:
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Neighborhood |
Gene Fusion |
Cooccurence |
Coexpression |
Experiments |
Databases |
Textmining |
[Homology] |
Score |
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 | C9orf24 | chromosome 9 open reading frame 24; May play a role in spermatogenesis (By similarity). May be involved in differentiation or function of ciliated cells (262 aa) | ||||||||||||
Predicted Functional Partners:
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 | FOXJ1 | forkhead box J1; May play an important role in cell fate determination during lung development and in spermatogenesis (By similarity) (421 aa) |
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0.844 | ||||||||||
 | IL13 | interleukin 13; Cytokine. Inhibits inflammatory cytokine production. Synergizes with IL2 in regulating interferon-gamma synthesis. May be critical in regulating inflammatory and immune responses (146 aa) |
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0.805 | ||||||||||
 | ENKUR | enkurin, TRPC channel interacting protein; Adapter that functions to localize a calcium-sensitive signal transduction machinery in sperm to a calcium-permeable ion channel (By similarity) (256 aa) |
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0.618 | ||||||||||
 | MAATS1 | MYCBP/AMY-1-associated, testis expressed 1 (767 aa) |
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0.485 | ||||||||||
 | RIIAD1 | regulatory subunit of type II PKA R-subunit (RIIa) domain containing 1 (92 aa) |
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0.483 | ||||||||||
 | TCTEX1D2 | Tctex1 domain containing 2 (142 aa) |
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0.483 | ||||||||||
 | C6orf165 | chromosome 6 open reading frame 165 (622 aa) |
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0.482 | ||||||||||
 | CCDC113 | coiled-coil domain containing 113 (377 aa) |
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0.482 | ||||||||||
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man
Other names: H. sapiens, Homo, Homo sapiens, human, man
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