NOL6 protein (Homo sapiens) - STRING network view

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Score

NOL6

nucleolar protein family 6 (RNA-associated) (1146 aa)

Predicted Functional Partners:

HEATR1

0.997

PWP2

0.997

WDR36

0.997

NOP14

0.996

MPHOSPH10

0.994

WDR3

0.993

PDCD11

0.992

WDR75

0.992

NOC4L

0.990

UTP18

0.988

Your Current Organism:

Homo sapiens

NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
HEATR1	MPHOSPH10	ENSP00000355541	ENSP00000244230	HEAT repeat containing 1; Involved in nucleolar processing of pre-18S ribosomal RNA. Involved in ribosome biosynthesis (By similarity)	M-phase phosphoprotein 10 (U3 small nucleolar ribonucleoprotein); Component of the 60-80S U3 small nucleolar ribonucleoprotein (U3 snoRNP). Required for the early cleavages during pre-18S ribosomal RNA processing	0.994
HEATR1	NOC4L	ENSP00000355541	ENSP00000328854	HEAT repeat containing 1; Involved in nucleolar processing of pre-18S ribosomal RNA. Involved in ribosome biosynthesis (By similarity)	nucleolar complex associated 4 homolog (S. cerevisiae)	0.996
HEATR1	NOL6	ENSP00000355541	ENSP00000297990	HEAT repeat containing 1; Involved in nucleolar processing of pre-18S ribosomal RNA. Involved in ribosome biosynthesis (By similarity)	nucleolar protein family 6 (RNA-associated)	0.997
HEATR1	NOP14	ENSP00000355541	ENSP00000315674	HEAT repeat containing 1; Involved in nucleolar processing of pre-18S ribosomal RNA. Involved in ribosome biosynthesis (By similarity)	NOP14 nucleolar protein homolog (yeast); Involved in nucleolar processing of pre-18S ribosomal RNA. Has a role in the nuclear export of 40S pre-ribosomal subunit to the cytoplasm (By similarity)	0.994
HEATR1	PDCD11	ENSP00000355541	ENSP00000358812	HEAT repeat containing 1; Involved in nucleolar processing of pre-18S ribosomal RNA. Involved in ribosome biosynthesis (By similarity)	programmed cell death 11; Essential for the generation of mature 18S rRNA, specifically necessary for cleavages at sites A0, 1 and 2 of the 47S precursor. Directly interacts with U3 snoRNA	0.994
HEATR1	PWP2	ENSP00000355541	ENSP00000291576	HEAT repeat containing 1; Involved in nucleolar processing of pre-18S ribosomal RNA. Involved in ribosome biosynthesis (By similarity)	PWP2 periodic tryptophan protein homolog (yeast)	0.999
HEATR1	UTP18	ENSP00000355541	ENSP00000225298	HEAT repeat containing 1; Involved in nucleolar processing of pre-18S ribosomal RNA. Involved in ribosome biosynthesis (By similarity)	UTP18 small subunit (SSU) processome component homolog (yeast); Involved in nucleolar processing of pre-18S ribosomal RNA (By similarity)	0.995
HEATR1	WDR3	ENSP00000355541	ENSP00000308179	HEAT repeat containing 1; Involved in nucleolar processing of pre-18S ribosomal RNA. Involved in ribosome biosynthesis (By similarity)	WD repeat domain 3	0.996
HEATR1	WDR36	ENSP00000355541	ENSP00000423067	HEAT repeat containing 1; Involved in nucleolar processing of pre-18S ribosomal RNA. Involved in ribosome biosynthesis (By similarity)	WD repeat domain 36; Involved in T-cell activation and highly co-regulated with IL2	0.999
HEATR1	WDR75	ENSP00000355541	ENSP00000314193	HEAT repeat containing 1; Involved in nucleolar processing of pre-18S ribosomal RNA. Involved in ribosome biosynthesis (By similarity)	WD repeat domain 75	0.998
MPHOSPH10	HEATR1	ENSP00000244230	ENSP00000355541	M-phase phosphoprotein 10 (U3 small nucleolar ribonucleoprotein); Component of the 60-80S U3 small nucleolar ribonucleoprotein (U3 snoRNP). Required for the early cleavages during pre-18S ribosomal RNA processing	HEAT repeat containing 1; Involved in nucleolar processing of pre-18S ribosomal RNA. Involved in ribosome biosynthesis (By similarity)	0.994
MPHOSPH10	NOC4L	ENSP00000244230	ENSP00000328854	M-phase phosphoprotein 10 (U3 small nucleolar ribonucleoprotein); Component of the 60-80S U3 small nucleolar ribonucleoprotein (U3 snoRNP). Required for the early cleavages during pre-18S ribosomal RNA processing	nucleolar complex associated 4 homolog (S. cerevisiae)	0.977
MPHOSPH10	NOL6	ENSP00000244230	ENSP00000297990	M-phase phosphoprotein 10 (U3 small nucleolar ribonucleoprotein); Component of the 60-80S U3 small nucleolar ribonucleoprotein (U3 snoRNP). Required for the early cleavages during pre-18S ribosomal RNA processing	nucleolar protein family 6 (RNA-associated)	0.994
MPHOSPH10	NOP14	ENSP00000244230	ENSP00000315674	M-phase phosphoprotein 10 (U3 small nucleolar ribonucleoprotein); Component of the 60-80S U3 small nucleolar ribonucleoprotein (U3 snoRNP). Required for the early cleavages during pre-18S ribosomal RNA processing	NOP14 nucleolar protein homolog (yeast); Involved in nucleolar processing of pre-18S ribosomal RNA. Has a role in the nuclear export of 40S pre-ribosomal subunit to the cytoplasm (By similarity)	0.996
MPHOSPH10	PDCD11	ENSP00000244230	ENSP00000358812	M-phase phosphoprotein 10 (U3 small nucleolar ribonucleoprotein); Component of the 60-80S U3 small nucleolar ribonucleoprotein (U3 snoRNP). Required for the early cleavages during pre-18S ribosomal RNA processing	programmed cell death 11; Essential for the generation of mature 18S rRNA, specifically necessary for cleavages at sites A0, 1 and 2 of the 47S precursor. Directly interacts with U3 snoRNA	0.996
MPHOSPH10	PWP2	ENSP00000244230	ENSP00000291576	M-phase phosphoprotein 10 (U3 small nucleolar ribonucleoprotein); Component of the 60-80S U3 small nucleolar ribonucleoprotein (U3 snoRNP). Required for the early cleavages during pre-18S ribosomal RNA processing	PWP2 periodic tryptophan protein homolog (yeast)	0.997
MPHOSPH10	UTP18	ENSP00000244230	ENSP00000225298	M-phase phosphoprotein 10 (U3 small nucleolar ribonucleoprotein); Component of the 60-80S U3 small nucleolar ribonucleoprotein (U3 snoRNP). Required for the early cleavages during pre-18S ribosomal RNA processing	UTP18 small subunit (SSU) processome component homolog (yeast); Involved in nucleolar processing of pre-18S ribosomal RNA (By similarity)	0.948
MPHOSPH10	WDR3	ENSP00000244230	ENSP00000308179	M-phase phosphoprotein 10 (U3 small nucleolar ribonucleoprotein); Component of the 60-80S U3 small nucleolar ribonucleoprotein (U3 snoRNP). Required for the early cleavages during pre-18S ribosomal RNA processing	WD repeat domain 3	0.995
MPHOSPH10	WDR36	ENSP00000244230	ENSP00000423067	M-phase phosphoprotein 10 (U3 small nucleolar ribonucleoprotein); Component of the 60-80S U3 small nucleolar ribonucleoprotein (U3 snoRNP). Required for the early cleavages during pre-18S ribosomal RNA processing	WD repeat domain 36; Involved in T-cell activation and highly co-regulated with IL2	0.991
MPHOSPH10	WDR75	ENSP00000244230	ENSP00000314193	M-phase phosphoprotein 10 (U3 small nucleolar ribonucleoprotein); Component of the 60-80S U3 small nucleolar ribonucleoprotein (U3 snoRNP). Required for the early cleavages during pre-18S ribosomal RNA processing	WD repeat domain 75	0.992

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