node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ACTB | ACTG1 | ENSP00000349960 | ENSP00000331514 | actin, beta | actin, gamma 1; Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells | 0.943 |
ACTB | CAP1 | ENSP00000349960 | ENSP00000361878 | actin, beta | CAP, adenylate cyclase-associated protein 1 (yeast); Directly regulates filament dynamics and has been implicated in a number of complex developmental and morphological processes, including mRNA localization and the establishment of cell polarity | 0.890 |
ACTB | CAP2 | ENSP00000349960 | ENSP00000229922 | actin, beta | CAP, adenylate cyclase-associated protein, 2 (yeast); May have a regulatory bifunctional role | 0.944 |
ACTB | CFL2 | ENSP00000349960 | ENSP00000298159 | actin, beta | cofilin 2 (muscle); Controls reversibly actin polymerization and depolymerization in a pH-sensitive manner. It has the ability to bind G- and F-actin in a 1-1 ratio of cofilin to actin. It is the major component of intranuclear and cytoplasmic actin rods (By similarity) | 0.997 |
ACTB | SSH1 | ENSP00000349960 | ENSP00000315713 | actin, beta | slingshot homolog 1 (Drosophila); Protein phosphatase which regulates actin filament dynamics. Dephosphorylates and activates the actin binding/depolymerizing factor cofilin, which subsequently binds to actin filaments and stimulates their disassembly. Inhibitory phosphorylation of cofilin is mediated by LIMK1, which may also be dephosphorylated and inactivated by this protein | 0.585 |
ACTB | SSH2 | ENSP00000349960 | ENSP00000269033 | actin, beta | slingshot homolog 2 (Drosophila); Protein phosphatase which regulates actin filament dynamics. Dephosphorylates and activates the actin binding/depolymerizing factor cofilin, which subsequently binds to actin filaments and stimulates their disassembly. Inhibitory phosphorylation of cofilin is mediated by LIMK1, which may also be dephosphorylated and inactivated by this protein | 0.591 |
ACTB | SSH3 | ENSP00000349960 | ENSP00000312081 | actin, beta | slingshot homolog 3 (Drosophila); Protein phosphatase which may play a role in the regulation of actin filament dynamics. Can dephosphorylate and activate the actin binding/depolymerizing factor cofilin, which subsequently binds to actin filaments and stimulates their disassembly (By similarity) | 0.585 |
ACTB | UBC | ENSP00000349960 | ENSP00000344818 | actin, beta | ubiquitin C | 0.999 |
ACTB | WDR1 | ENSP00000349960 | ENSP00000427687 | actin, beta | WD repeat domain 1; Induces disassembly of actin filaments in conjunction with ADF/cofilin family proteins (By similarity) | 0.930 |
ACTG1 | ACTB | ENSP00000331514 | ENSP00000349960 | actin, gamma 1; Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells | actin, beta | 0.943 |
ACTG1 | CAP1 | ENSP00000331514 | ENSP00000361878 | actin, gamma 1; Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells | CAP, adenylate cyclase-associated protein 1 (yeast); Directly regulates filament dynamics and has been implicated in a number of complex developmental and morphological processes, including mRNA localization and the establishment of cell polarity | 0.888 |
ACTG1 | CAP2 | ENSP00000331514 | ENSP00000229922 | actin, gamma 1; Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells | CAP, adenylate cyclase-associated protein, 2 (yeast); May have a regulatory bifunctional role | 0.974 |
ACTG1 | CFL2 | ENSP00000331514 | ENSP00000298159 | actin, gamma 1; Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells | cofilin 2 (muscle); Controls reversibly actin polymerization and depolymerization in a pH-sensitive manner. It has the ability to bind G- and F-actin in a 1-1 ratio of cofilin to actin. It is the major component of intranuclear and cytoplasmic actin rods (By similarity) | 0.985 |
ACTG1 | UBC | ENSP00000331514 | ENSP00000344818 | actin, gamma 1; Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells | ubiquitin C | 0.998 |
ACTG1 | WDR1 | ENSP00000331514 | ENSP00000427687 | actin, gamma 1; Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells | WD repeat domain 1; Induces disassembly of actin filaments in conjunction with ADF/cofilin family proteins (By similarity) | 0.930 |
CAP1 | ACTB | ENSP00000361878 | ENSP00000349960 | CAP, adenylate cyclase-associated protein 1 (yeast); Directly regulates filament dynamics and has been implicated in a number of complex developmental and morphological processes, including mRNA localization and the establishment of cell polarity | actin, beta | 0.890 |
CAP1 | ACTG1 | ENSP00000361878 | ENSP00000331514 | CAP, adenylate cyclase-associated protein 1 (yeast); Directly regulates filament dynamics and has been implicated in a number of complex developmental and morphological processes, including mRNA localization and the establishment of cell polarity | actin, gamma 1; Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells | 0.888 |
CAP1 | CAP2 | ENSP00000361878 | ENSP00000229922 | CAP, adenylate cyclase-associated protein 1 (yeast); Directly regulates filament dynamics and has been implicated in a number of complex developmental and morphological processes, including mRNA localization and the establishment of cell polarity | CAP, adenylate cyclase-associated protein, 2 (yeast); May have a regulatory bifunctional role | 0.955 |
CAP1 | CFL2 | ENSP00000361878 | ENSP00000298159 | CAP, adenylate cyclase-associated protein 1 (yeast); Directly regulates filament dynamics and has been implicated in a number of complex developmental and morphological processes, including mRNA localization and the establishment of cell polarity | cofilin 2 (muscle); Controls reversibly actin polymerization and depolymerization in a pH-sensitive manner. It has the ability to bind G- and F-actin in a 1-1 ratio of cofilin to actin. It is the major component of intranuclear and cytoplasmic actin rods (By similarity) | 0.917 |
CAP1 | UBC | ENSP00000361878 | ENSP00000344818 | CAP, adenylate cyclase-associated protein 1 (yeast); Directly regulates filament dynamics and has been implicated in a number of complex developmental and morphological processes, including mRNA localization and the establishment of cell polarity | ubiquitin C | 0.816 |