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STRINGSTRING
ACAA2 ACAA2 ACAA1 ACAA1 ACAT2 ACAT2 ECI2 ECI2 ACADM ACADM ECHDC2 ECHDC2 GCDH GCDH ACAT1 ACAT1 ECI1 ECI1 CRYL1 CRYL1 HADHB HADHB
"CRYL1" - crystallin, lambda 1 in Homo sapiens
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Size
small protein node
small nodes:
protein of unknown 3D structure
large protein node
large nodes:
some 3D structure is known or predicted
Node Color
colored protein node
colored nodes:
query proteins and first shell of interactors
non-colored protein node
white nodes:
second shell of interactors
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
database edge
from curated databases
experiment edge
experimentally determined
Predicted Interactions
neighborhood edge
gene neighborhood
fusion edge
gene fusions
cooccurrence edge
gene co-occurrence
Others
textmining edge
textmining
coexpression edge
co-expression
homology edge
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CRYL1crystallin, lambda 1 (319 aa)    
Predicted Functional Partners:
ACAT2
acetyl-CoA acetyltransferase 2 (397 aa)
score_image     score_image score_image   score_image   0.775
ACAA1
acetyl-CoA acyltransferase 1 (424 aa)
score_image     score_image score_image   score_image   0.775
HADHB
hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), beta subunit (474 aa)
score_image     score_image score_image   score_image   0.775
ACAA2
acetyl-CoA acyltransferase 2; Abolishes BNIP3-mediated apoptosis and mitochondrial damage (397 aa)
score_image     score_image score_image   score_image   0.775
ACAT1
acetyl-CoA acetyltransferase 1; Plays a major role in ketone body metabolism (427 aa)
score_image     score_image score_image   score_image   0.775
ECI1
enoyl-CoA delta isomerase 1; Able to isomerize both 3-cis and 3-trans double bonds into the 2-trans form in a range of enoyl-CoA species (302 aa)
score_image   score_image score_image     score_image   0.738
ECHDC2
enoyl CoA hydratase domain containing 2 (292 aa)
score_image   score_image score_image     score_image   0.690
GCDH
glutaryl-CoA dehydrogenase; Catalyzes the oxidative decarboxylation of glutaryl-CoA to crotonyl-CoA and CO(2) in the degradative pathway of L-lysine, L-hydroxylysine, and L-tryptophan metabolism. It uses electron transfer flavoprotein as its electron acceptor. Isoform Short is inactive (438 aa)
score_image     score_image     score_image   0.659
ECI2
enoyl-CoA delta isomerase 2 (394 aa)
score_image     score_image     score_image   0.648
ACADM
acyl-CoA dehydrogenase, C-4 to C-12 straight chain; This enzyme is specific for acyl chain lengths of 4 to 16 (425 aa)
score_image     score_image     score_image   0.643
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man
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