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SLC30A5 SLC30A5 SLC39A14 SLC39A14 SLC30A6 SLC30A6 KCNAB2 KCNAB2 SLC39A4 SLC39A4 SLC39A2 SLC39A2 SLC39A11 SLC39A11 SLC30A1 SLC30A1 SLC39A5 SLC39A5 SLC39A8 SLC39A8 SLC30A7 SLC30A7
"SLC39A2" - solute carrier family 39 (zinc transporter), member 2 in Homo sapiens
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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protein of unknown 3D structure
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some 3D structure is known or predicted
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query proteins and first shell of interactors
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second shell of interactors
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Predicted Interactions
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protein homology
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SLC39A2solute carrier family 39 (zinc transporter), member 2; Mediates zinc uptake. Zinc uptake may be mediated by a Zn(2+)-HCO(3)(-) symport mechanism and can function in the presence of albumin. May also transport other divalent cations. May be important in contact inhibition of normal epithelial cells and loss of its expression may play a role in tumorigenesis (309 aa)    
Predicted Functional Partners:
SLC39A4
solute carrier family 39 (zinc transporter), member 4; Plays an important role in cellular zinc homeostasis as a zinc transporter. Regulated in response to zinc availability (By similarity) (647 aa)
        score_image   score_image   0.904
SLC30A1
solute carrier family 30 (zinc transporter), member 1; May be involved in zinc transport out of the cell (507 aa)
      score_image     score_image   0.863
SLC39A5
solute carrier family 39 (metal ion transporter), member 5; May play a role in polarized cells by carrying out serosal-to-mucosal zinc transport. Seems to play a central role in controlling organismal zinc status (By similarity) (540 aa)
        score_image   score_image   0.852
SLC30A5
solute carrier family 30 (zinc transporter), member 5; Functions as a zinc transporter. May be a transporter of zinc into beta cells in order to form insulin crystals. Partly regulates cellular zinc homeostasis. Required with ZNT7 for the activation of zinc-requiring enzymes, alkaline phosphatases (ALPs). Transports zinc into the lumens of the Golgi apparatus and vesicular compartments where ALPs locate, thus, converting apoALPs to holoALPs. Required with ZNT6 and ZNT7 for the activation of TNAP (765 aa)
      score_image     score_image   0.829
KCNAB2
potassium voltage-gated channel, shaker-related subfamily, beta member 2 (415 aa)
        score_image   score_image   0.824
SLC39A11
solute carrier family 39 (metal ion transporter), member 11; May act as a zinc-influx transporter (By similarity) (342 aa)
        score_image   score_image   0.806
SLC39A14
solute carrier family 39 (zinc transporter), member 14; May mediate cellular uptake of nontransferrin-bound iron (By similarity). Broad-scope metal ion transporter with a preference for zinc uptake (492 aa)
        score_image   score_image   0.794
SLC39A8
solute carrier family 39 (zinc transporter), member 8; Acts as a zinc-influx transporter (460 aa)
        score_image   score_image   0.792
SLC30A6
solute carrier family 30 (zinc transporter), member 6; Zinc-efflux transporter which allocates the cytoplasmic zinc to the trans-Golgi network (TGN) as well as the vesicular compartment (By similarity) (501 aa)
      score_image     score_image   0.791
SLC30A7
solute carrier family 30 (zinc transporter), member 7; Seems to facilitate zinc transport from the cytoplasm into the Golgi apparatus. Partly regulates cellular zinc homeostasis. Required with ZNT5 for the activation of zinc- requiring enzymes, alkaline phosphatases (ALPs). Transports zinc into the lumens of the Golgi apparatus and the vesicular compartments where ALPs locate, thus, converting apoALPs to holoALPs. Required with ZNT5 and ZNT6 for the activation of TNAP (By similarity) (376 aa)
      score_image     score_image   0.791
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man
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