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GTF3C3 GTF3C3 CSTF2 CSTF2 CSTF3 CSTF3 CSTF1 CSTF1 CPSF3 CPSF3 CPSF1 CPSF1 CPSF2 CPSF2 CPSF4 CPSF4 FIP1L1 FIP1L1 WDR33 WDR33 SSU72 SSU72
"CPSF2" - cleavage and polyadenylation specific factor 2, 100kDa in Homo sapiens
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CPSF2cleavage and polyadenylation specific factor 2, 100kDa; Component of the cleavage and polyadenylation specificity factor (CPSF) complex that play a key role in pre-mRNA 3’-end formation, recognizing the AAUAAA signal sequence and interacting with poly(A) polymerase and other factors to bring about cleavage and poly(A) addition. Involved in the histone 3’ end pre-mRNA processing (782 aa)    
Predicted Functional Partners:
FIP1L1
FIP1 like 1 (S. cerevisiae) (594 aa)
         score_image score_image score_image   0.999
CPSF3
cleavage and polyadenylation specific factor 3, 73kDa; Component of the cleavage and polyadenylation specificity factor (CPSF) complex that play a key role in pre-mRNA 3’-end formation, recognizing the AAUAAA signal sequence and interacting with poly(A) polymerase and other factors to bring about cleavage and poly(A) addition. Has endonuclease activity, and functions as mRNA 3’-end-processing endonuclease. Also involved in the histone 3’-end pre-mRNA processing. U7 snRNP- dependent protein that induces both the 3’-endoribonucleolytic cleavage of histone pre-mRNAs and acts as a 5’ to 3’ [...] (684 aa)
       score_image score_image score_image score_image score_image 0.999
WDR33
WD repeat domain 33; Essential for both cleavage and polyadenylation of pre- mRNA 3’ ends (1336 aa)
       score_image score_image score_image score_image   0.999
CPSF4
cleavage and polyadenylation specific factor 4, 30kDa; Component of the cleavage and polyadenylation specificity factor (CPSF) complex that play a key role in pre-mRNA 3’-end formation, recognizing the AAUAAA signal sequence and interacting with poly(A) polymerase and other factors to bring about cleavage and poly(A) addition. CPSF4 binds RNA polymers with a preference for poly(U) (269 aa)
         score_image score_image score_image   0.999
CSTF2
cleavage stimulation factor, 3’ pre-RNA, subunit 2, 64kDa; One of the multiple factors required for polyadenylation and 3’-end cleavage of mammalian pre-mRNAs. This subunit is directly involved in the binding to pre-mRNAs (By similarity) (577 aa)
       score_image score_image score_image score_image   0.999
CPSF1
cleavage and polyadenylation specific factor 1, 160kDa; Component of the cleavage and polyadenylation specificity factor (CPSF) complex that plays a key role in pre- mRNA 3’-end formation, recognizing the AAUAAA signal sequence and interacting with poly(A) polymerase and other factors to bring about cleavage and poly(A) addition. This subunit is involved in the RNA recognition step of the polyadenylation reaction (1443 aa)
       score_image score_image score_image score_image   0.998
CSTF3
cleavage stimulation factor, 3’ pre-RNA, subunit 3, 77kDa; One of the multiple factors required for polyadenylation and 3’-end cleavage of mammalian pre-mRNAs (717 aa)
       score_image score_image score_image score_image   0.998
GTF3C3
general transcription factor IIIC, polypeptide 3, 102kDa; Involved in RNA polymerase III-mediated transcription. Integral, tightly associated component of the DNA-binding TFIIIC2 subcomplex that directly binds tRNA and virus-associated RNA promoters (886 aa)
         score_image       0.998
CSTF1
cleavage stimulation factor, 3’ pre-RNA, subunit 1, 50kDa; One of the multiple factors required for polyadenylation and 3’-end cleavage of mammalian pre-mRNAs. May be responsible for the interaction of CSTF with other factors to form a stable complex on the pre-mRNA (431 aa)
       score_image score_image score_image score_image   0.998
SSU72
SSU72 RNA polymerase II CTD phosphatase homolog (S. cerevisiae); Protein phosphatase that catalyzes the dephosphorylation of the C-terminal domain of RNA polymerase II. Plays a role in RNA processing and termination. Plays a role in pre-mRNA polyadenylation via its interaction with SYMPK (194 aa)
         score_image score_image score_image   0.996
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man
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