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USP15 USP15 LDHC LDHC ASB9 ASB9 UBC UBC CKM CKM GAMT GAMT LDHB LDHB CKB CKB CLPB CLPB LDHA LDHA USPL1 USPL1
"CKB" - creatine kinase, brain in Homo sapiens
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protein of unknown 3D structure
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Predicted Interactions
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CKBcreatine kinase, brain; Reversibly catalyzes the transfer of phosphate between ATP and various phosphogens (e.g. creatine phosphate). Creatine kinase isoenzymes play a central role in energy transduction in tissues with large, fluctuating energy demands, such as skeletal muscle, heart, brain and spermatozoa (381 aa)    
Predicted Functional Partners:
ASB9
ankyrin repeat and SOCS box containing 9; Substrate-recognition component of a SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. Recognizes at least two forms of creatine kinase, CKB and CKMT1A (294 aa)
        score_image   score_image   0.979
UBC
ubiquitin C (685 aa)
        score_image   score_image   0.968
CKM
creatine kinase, muscle; Reversibly catalyzes the transfer of phosphate between ATP and various phosphogens (e.g. creatine phosphate). Creatine kinase isoenzymes play a central role in energy transduction in tissues with large, fluctuating energy demands, such as skeletal muscle, heart, brain and spermatozoa (381 aa)
    score_image   score_image score_image score_image score_image 0.956
GAMT
guanidinoacetate N-methyltransferase (269 aa)
          score_image score_image   0.931
LDHB
lactate dehydrogenase B (334 aa)
        score_image   score_image   0.894
LDHC
lactate dehydrogenase C; Possible role in sperm motility (332 aa)
            score_image   0.812
CLPB
ClpB caseinolytic peptidase B homolog (E. coli); May function as a regulatory ATPase and be related to secretion/protein trafficking process (707 aa)
score_image     score_image score_image   score_image   0.777
LDHA
lactate dehydrogenase A (361 aa)
            score_image   0.756
USP15
ubiquitin specific peptidase 15; Hydrolase that removes conjugated ubiquitin from target proteins and regulates various pathways such as the TGF-beta receptor signaling and NF-kappa-B pathways. Acts as a key regulator of TGF-beta receptor signaling pathway, but the precise mechanism is still unclear- according to a report, acts by promoting deubiquitination of monoubiquitinated R-SMADs (SMAD1, SMAD2 and/or SMAD3), thereby alleviating inhibition of R-SMADs and promoting activation of TGF-beta target genes (PubMed-21947082). According to another reports, regulates the TGF-beta receptor s [...] (952 aa)
        score_image       0.740
USPL1
ubiquitin specific peptidase like 1; SUMO-specific isopeptidase involved in protein desumoylation. Specifically binds SUMO proteins with a higher affinity for SUMO2 and SUMO3 which it cleaves more efficiently. Also able to process full-length SUMO proteins to their mature forms. May have non-catalytic functions in Cajal bodies organization and cell proliferation (1092 aa)
        score_image       0.740
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man
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