node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
CHAF1B | CHODL | ENSP00000315700 | ENSP00000299295 | chromatin assembly factor 1, subunit B (p60); Complex that is thought to mediate chromatin assembly in DNA replication and DNA repair. Assembles histone octamers onto replicating DNA in vitro. CAF-1 performs the first step of the nucleosome assembly process, bringing newly synthesized histones H3 and H4 to replicating DNA; histones H2A/H2B can bind to this chromatin precursor subsequent to DNA replication to complete the histone octamer | chondrolectin | 0.493 |
CHAF1B | CLDN8 | ENSP00000315700 | ENSP00000286809 | chromatin assembly factor 1, subunit B (p60); Complex that is thought to mediate chromatin assembly in DNA replication and DNA repair. Assembles histone octamers onto replicating DNA in vitro. CAF-1 performs the first step of the nucleosome assembly process, bringing newly synthesized histones H3 and H4 to replicating DNA; histones H2A/H2B can bind to this chromatin precursor subsequent to DNA replication to complete the histone octamer | claudin 8; Plays a major role in tight junction-specific obliteration of the intercellular space (By similarity) | 0.528 |
CHODL | CHAF1B | ENSP00000299295 | ENSP00000315700 | chondrolectin | chromatin assembly factor 1, subunit B (p60); Complex that is thought to mediate chromatin assembly in DNA replication and DNA repair. Assembles histone octamers onto replicating DNA in vitro. CAF-1 performs the first step of the nucleosome assembly process, bringing newly synthesized histones H3 and H4 to replicating DNA; histones H2A/H2B can bind to this chromatin precursor subsequent to DNA replication to complete the histone octamer | 0.493 |
CHODL | CLDN17 | ENSP00000299295 | ENSP00000286808 | chondrolectin | claudin 17; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium- independent cell-adhesion activity (By similarity) | 0.483 |
CHODL | CLDN8 | ENSP00000299295 | ENSP00000286809 | chondrolectin | claudin 8; Plays a major role in tight junction-specific obliteration of the intercellular space (By similarity) | 0.677 |
CHODL | COL23A1 | ENSP00000299295 | ENSP00000375069 | chondrolectin | collagen, type XXIII, alpha 1 | 0.426 |
CHODL | CXADR | ENSP00000299295 | ENSP00000284878 | chondrolectin | coxsackie virus and adenovirus receptor; Component of the epithelial apical junction complex that is essential for the tight junction integrity. Proposed to function as a homophilic cell adhesion molecule. Recruits MPDZ to intercellular contact sites. Probably involved in transepithelial migration of polymorphonuclear leukocytes (PMN) through adhesive interactions with AMICA1/JAML located in the plasma membrane of PMN | 0.566 |
CHODL | FAM165B | ENSP00000299295 | ENSP00000382231 | chondrolectin | family with sequence similarity 165, member B | 0.405 |
CHODL | KCNJ15 | ENSP00000299295 | ENSP00000331698 | chondrolectin | potassium inwardly-rectifying channel, subfamily J, member 15; Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Their voltage dependence is regulated by the concentration of extracellular potassium; as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages. The inward rectification is mainly due to the blockage of outward current by internal magnesium | 0.434 |
CHODL | RSPO4 | ENSP00000299295 | ENSP00000217260 | chondrolectin | R-spondin 4; Activator of the beta-catenin signaling cascade, leading to TCF-dependent gene activation. Acts both in the canonical Wnt/beta-catenin-dependent pathway and in non-canonical Wnt signaling pathway, probably by acting as an inhibitor of ZNRF3, an important regulator of the Wnt signaling pathway (By similarity) | 0.548 |
CHODL | SMYD4 | ENSP00000299295 | ENSP00000304360 | chondrolectin | SET and MYND domain containing 4 | 0.474 |
CHODL | TMEM45B | ENSP00000299295 | ENSP00000281441 | chondrolectin | transmembrane protein 45B | 0.468 |
CLDN17 | CHODL | ENSP00000286808 | ENSP00000299295 | claudin 17; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium- independent cell-adhesion activity (By similarity) | chondrolectin | 0.483 |
CLDN17 | CLDN8 | ENSP00000286808 | ENSP00000286809 | claudin 17; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium- independent cell-adhesion activity (By similarity) | claudin 8; Plays a major role in tight junction-specific obliteration of the intercellular space (By similarity) | 0.804 |
CLDN8 | CHAF1B | ENSP00000286809 | ENSP00000315700 | claudin 8; Plays a major role in tight junction-specific obliteration of the intercellular space (By similarity) | chromatin assembly factor 1, subunit B (p60); Complex that is thought to mediate chromatin assembly in DNA replication and DNA repair. Assembles histone octamers onto replicating DNA in vitro. CAF-1 performs the first step of the nucleosome assembly process, bringing newly synthesized histones H3 and H4 to replicating DNA; histones H2A/H2B can bind to this chromatin precursor subsequent to DNA replication to complete the histone octamer | 0.528 |
CLDN8 | CHODL | ENSP00000286809 | ENSP00000299295 | claudin 8; Plays a major role in tight junction-specific obliteration of the intercellular space (By similarity) | chondrolectin | 0.677 |
CLDN8 | CLDN17 | ENSP00000286809 | ENSP00000286808 | claudin 8; Plays a major role in tight junction-specific obliteration of the intercellular space (By similarity) | claudin 17; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium- independent cell-adhesion activity (By similarity) | 0.804 |
CLDN8 | KCNJ15 | ENSP00000286809 | ENSP00000331698 | claudin 8; Plays a major role in tight junction-specific obliteration of the intercellular space (By similarity) | potassium inwardly-rectifying channel, subfamily J, member 15; Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Their voltage dependence is regulated by the concentration of extracellular potassium; as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages. The inward rectification is mainly due to the blockage of outward current by internal magnesium | 0.480 |
CLDN8 | TMEM45B | ENSP00000286809 | ENSP00000281441 | claudin 8; Plays a major role in tight junction-specific obliteration of the intercellular space (By similarity) | transmembrane protein 45B | 0.449 |
COL23A1 | CHODL | ENSP00000375069 | ENSP00000299295 | collagen, type XXIII, alpha 1 | chondrolectin | 0.426 |