node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
AS3MT | C10orf32 | ENSP00000358896 | ENSP00000299353 | arsenic (+3 oxidation state) methyltransferase; Catalyzes the transfer of a methyl group from AdoMet to trivalent arsenicals producing methylated and dimethylated arsenicals. It methylates arsenite to form methylarsonate, Me- AsO(3)H(2), which is reduced by methylarsonate reductase to methylarsonite, Me-As(OH)2. Methylarsonite is also a substrate and it is converted into the much less toxic compound dimethylarsinate (cacodylate), Me(2)As(O)-OH (By similarity) | chromosome 10 open reading frame 32 | 0.538 |
C10orf32 | AS3MT | ENSP00000299353 | ENSP00000358896 | chromosome 10 open reading frame 32 | arsenic (+3 oxidation state) methyltransferase; Catalyzes the transfer of a methyl group from AdoMet to trivalent arsenicals producing methylated and dimethylated arsenicals. It methylates arsenite to form methylarsonate, Me- AsO(3)H(2), which is reduced by methylarsonate reductase to methylarsonite, Me-As(OH)2. Methylarsonite is also a substrate and it is converted into the much less toxic compound dimethylarsinate (cacodylate), Me(2)As(O)-OH (By similarity) | 0.538 |
C10orf32 | C1orf131 | ENSP00000299353 | ENSP00000355609 | chromosome 10 open reading frame 32 | chromosome 1 open reading frame 131 | 0.567 |
C10orf32 | CALHM2 | ENSP00000299353 | ENSP00000260743 | chromosome 10 open reading frame 32 | calcium homeostasis modulator 2; Pore-forming subunit of a voltage-gated ion channel (By similarity) | 0.472 |
C10orf32 | CALHM3 | ENSP00000299353 | ENSP00000358798 | chromosome 10 open reading frame 32 | calcium homeostasis modulator 3; Pore-forming subunit of a voltage-gated ion channel (By similarity) | 0.581 |
C10orf32 | CATSPER3 | ENSP00000299353 | ENSP00000282611 | chromosome 10 open reading frame 32 | cation channel, sperm associated 3; Voltage-gated calcium channel that plays a central role in calcium-dependent physiological responses essential for successful fertilization, such as sperm hyperactivation, acrosome reaction and chemotaxis towards the oocyte. Activated by extracellular progesterone and prostaglandins following the sequence- progesterone > PGF1-alpha = PGE1 > PGA1 > PGE2 >> PGD2. The primary effect of progesterone activation is to shift voltage dependence towards more physiological, negative membrane potentials; it is not mediated by metabotropic receptors and second m [...] | 0.459 |
C10orf32 | GTF3C6 | ENSP00000299353 | ENSP00000357863 | chromosome 10 open reading frame 32 | general transcription factor IIIC, polypeptide 6, alpha 35kDa; Involved in RNA polymerase III-mediated transcription. Integral, tightly associated component of the DNA-binding TFIIIC2 subcomplex that directly binds tRNA and virus-associated RNA promoters | 0.504 |
C10orf32 | MFSD1 | ENSP00000299353 | ENSP00000403117 | chromosome 10 open reading frame 32 | major facilitator superfamily domain containing 1 | 0.418 |
C10orf32 | SFXN2 | ENSP00000299353 | ENSP00000358909 | chromosome 10 open reading frame 32 | sideroflexin 2; Potential iron transporter | 0.472 |
C10orf32 | SLC38A9 | ENSP00000299353 | ENSP00000316596 | chromosome 10 open reading frame 32 | solute carrier family 38, member 9; Putative sodium-dependent amino acid/proton antiporter (By similarity) | 0.471 |
C10orf32 | UBC | ENSP00000299353 | ENSP00000344818 | chromosome 10 open reading frame 32 | ubiquitin C | 0.483 |
C1orf131 | C10orf32 | ENSP00000355609 | ENSP00000299353 | chromosome 1 open reading frame 131 | chromosome 10 open reading frame 32 | 0.567 |
C1orf131 | CATSPER3 | ENSP00000355609 | ENSP00000282611 | chromosome 1 open reading frame 131 | cation channel, sperm associated 3; Voltage-gated calcium channel that plays a central role in calcium-dependent physiological responses essential for successful fertilization, such as sperm hyperactivation, acrosome reaction and chemotaxis towards the oocyte. Activated by extracellular progesterone and prostaglandins following the sequence- progesterone > PGF1-alpha = PGE1 > PGA1 > PGE2 >> PGD2. The primary effect of progesterone activation is to shift voltage dependence towards more physiological, negative membrane potentials; it is not mediated by metabotropic receptors and second m [...] | 0.499 |
C1orf131 | GTF3C6 | ENSP00000355609 | ENSP00000357863 | chromosome 1 open reading frame 131 | general transcription factor IIIC, polypeptide 6, alpha 35kDa; Involved in RNA polymerase III-mediated transcription. Integral, tightly associated component of the DNA-binding TFIIIC2 subcomplex that directly binds tRNA and virus-associated RNA promoters | 0.531 |
C1orf131 | MFSD1 | ENSP00000355609 | ENSP00000403117 | chromosome 1 open reading frame 131 | major facilitator superfamily domain containing 1 | 0.472 |
C1orf131 | SLC38A9 | ENSP00000355609 | ENSP00000316596 | chromosome 1 open reading frame 131 | solute carrier family 38, member 9; Putative sodium-dependent amino acid/proton antiporter (By similarity) | 0.502 |
CALHM2 | C10orf32 | ENSP00000260743 | ENSP00000299353 | calcium homeostasis modulator 2; Pore-forming subunit of a voltage-gated ion channel (By similarity) | chromosome 10 open reading frame 32 | 0.472 |
CALHM3 | C10orf32 | ENSP00000358798 | ENSP00000299353 | calcium homeostasis modulator 3; Pore-forming subunit of a voltage-gated ion channel (By similarity) | chromosome 10 open reading frame 32 | 0.581 |
CALHM3 | SFXN2 | ENSP00000358798 | ENSP00000358909 | calcium homeostasis modulator 3; Pore-forming subunit of a voltage-gated ion channel (By similarity) | sideroflexin 2; Potential iron transporter | 0.511 |
CATSPER3 | C10orf32 | ENSP00000282611 | ENSP00000299353 | cation channel, sperm associated 3; Voltage-gated calcium channel that plays a central role in calcium-dependent physiological responses essential for successful fertilization, such as sperm hyperactivation, acrosome reaction and chemotaxis towards the oocyte. Activated by extracellular progesterone and prostaglandins following the sequence- progesterone > PGF1-alpha = PGE1 > PGA1 > PGE2 >> PGD2. The primary effect of progesterone activation is to shift voltage dependence towards more physiological, negative membrane potentials; it is not mediated by metabotropic receptors and second m [...] | chromosome 10 open reading frame 32 | 0.459 |