| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| BBOX1 | TRIM17 | ENSP00000263182 | ENSP00000295033 | butyrobetaine (gamma), 2-oxoglutarate dioxygenase (gamma-butyrobetaine hydroxylase) 1; Catalyzes the formation of L-carnitine from gamma- butyrobetaine | tripartite motif containing 17; May function as an ubiquitin E3 ligase | 0.824 |
| BBOX1 | TRIM44 | ENSP00000263182 | ENSP00000299413 | butyrobetaine (gamma), 2-oxoglutarate dioxygenase (gamma-butyrobetaine hydroxylase) 1; Catalyzes the formation of L-carnitine from gamma- butyrobetaine | tripartite motif containing 44; May play a role in the process of differentiation and maturation of neuronal cells (By similarity). May regulate the activity of TRIM17 | 0.561 |
| BBOX1 | USP39 | ENSP00000263182 | ENSP00000312981 | butyrobetaine (gamma), 2-oxoglutarate dioxygenase (gamma-butyrobetaine hydroxylase) 1; Catalyzes the formation of L-carnitine from gamma- butyrobetaine | ubiquitin specific peptidase 39 | 0.562 |
| FJX1 | TRAF6 | ENSP00000400223 | ENSP00000337853 | four jointed box 1 (Drosophila); Acts as an inhibitor of dendrite extension and branching (By similarity) | TNF receptor-associated factor 6, E3 ubiquitin protein ligase; E3 ubiquitin ligase that, together with UBE2N and UBE2V1, mediates the synthesis of ’Lys-63’-linked-polyubiquitin chains conjugated to proteins, such as IKBKG, AKT1 and AKT2. Also mediates ubiquitination of free/unanchored polyubiquitin chain that leads to MAP3K7 activation. Leads to the activation of NF- kappa-B and JUN. May be essential for the formation of functional osteoclasts. Seems to also play a role in dendritic cells (DCs) maturation and/or activation. Represses c-Myb-mediated transactivation, in B-lymphocytes. Ad [...] | 0.518 |
| FJX1 | TRIM44 | ENSP00000400223 | ENSP00000299413 | four jointed box 1 (Drosophila); Acts as an inhibitor of dendrite extension and branching (By similarity) | tripartite motif containing 44; May play a role in the process of differentiation and maturation of neuronal cells (By similarity). May regulate the activity of TRIM17 | 0.860 |
| FJX1 | USP39 | ENSP00000400223 | ENSP00000312981 | four jointed box 1 (Drosophila); Acts as an inhibitor of dendrite extension and branching (By similarity) | ubiquitin specific peptidase 39 | 0.657 |
| HINFP | TRIM44 | ENSP00000318085 | ENSP00000299413 | histone H4 transcription factor; Transcriptional repressor that binds to the consensus sequence 5’-CGGACGTT-3’ and to the RB1 promoter. Transcriptional activator that promotes histone H4 gene transcription at the G1/S phase transition in conjunction with NPAT. Also activates transcription of the ATM and PRKDC genes. Autoregulates its expression by associating with its own promoter | tripartite motif containing 44; May play a role in the process of differentiation and maturation of neuronal cells (By similarity). May regulate the activity of TRIM17 | 0.487 |
| MC3R | MC5R | ENSP00000243911 | ENSP00000318077 | melanocortin 3 receptor; Receptor for MSH (alpha, beta and gamma) and ACTH. This receptor is mediated by G proteins which activate adenylate cyclase | melanocortin 5 receptor; Receptor for MSH (alpha, beta and gamma) and ACTH. The activity of this receptor is mediated by G proteins which activate adenylate cyclase. This receptor is a possible mediator of the immunomodulation properties of melanocortins | 0.902 |
| MC3R | TRIM44 | ENSP00000243911 | ENSP00000299413 | melanocortin 3 receptor; Receptor for MSH (alpha, beta and gamma) and ACTH. This receptor is mediated by G proteins which activate adenylate cyclase | tripartite motif containing 44; May play a role in the process of differentiation and maturation of neuronal cells (By similarity). May regulate the activity of TRIM17 | 0.532 |
| MC5R | MC3R | ENSP00000318077 | ENSP00000243911 | melanocortin 5 receptor; Receptor for MSH (alpha, beta and gamma) and ACTH. The activity of this receptor is mediated by G proteins which activate adenylate cyclase. This receptor is a possible mediator of the immunomodulation properties of melanocortins | melanocortin 3 receptor; Receptor for MSH (alpha, beta and gamma) and ACTH. This receptor is mediated by G proteins which activate adenylate cyclase | 0.902 |
| MC5R | TRIM44 | ENSP00000318077 | ENSP00000299413 | melanocortin 5 receptor; Receptor for MSH (alpha, beta and gamma) and ACTH. The activity of this receptor is mediated by G proteins which activate adenylate cyclase. This receptor is a possible mediator of the immunomodulation properties of melanocortins | tripartite motif containing 44; May play a role in the process of differentiation and maturation of neuronal cells (By similarity). May regulate the activity of TRIM17 | 0.472 |
| PBX3 | TRIM44 | ENSP00000362588 | ENSP00000299413 | pre-B-cell leukemia homeobox 3; Transcriptional activator that binds the sequence 5’- ATCAATCAA-3’ | tripartite motif containing 44; May play a role in the process of differentiation and maturation of neuronal cells (By similarity). May regulate the activity of TRIM17 | 0.489 |
| TRAF6 | FJX1 | ENSP00000337853 | ENSP00000400223 | TNF receptor-associated factor 6, E3 ubiquitin protein ligase; E3 ubiquitin ligase that, together with UBE2N and UBE2V1, mediates the synthesis of ’Lys-63’-linked-polyubiquitin chains conjugated to proteins, such as IKBKG, AKT1 and AKT2. Also mediates ubiquitination of free/unanchored polyubiquitin chain that leads to MAP3K7 activation. Leads to the activation of NF- kappa-B and JUN. May be essential for the formation of functional osteoclasts. Seems to also play a role in dendritic cells (DCs) maturation and/or activation. Represses c-Myb-mediated transactivation, in B-lymphocytes. Ad [...] | four jointed box 1 (Drosophila); Acts as an inhibitor of dendrite extension and branching (By similarity) | 0.518 |
| TRAF6 | TRIM17 | ENSP00000337853 | ENSP00000295033 | TNF receptor-associated factor 6, E3 ubiquitin protein ligase; E3 ubiquitin ligase that, together with UBE2N and UBE2V1, mediates the synthesis of ’Lys-63’-linked-polyubiquitin chains conjugated to proteins, such as IKBKG, AKT1 and AKT2. Also mediates ubiquitination of free/unanchored polyubiquitin chain that leads to MAP3K7 activation. Leads to the activation of NF- kappa-B and JUN. May be essential for the formation of functional osteoclasts. Seems to also play a role in dendritic cells (DCs) maturation and/or activation. Represses c-Myb-mediated transactivation, in B-lymphocytes. Ad [...] | tripartite motif containing 17; May function as an ubiquitin E3 ligase | 0.524 |
| TRAF6 | TRIM44 | ENSP00000337853 | ENSP00000299413 | TNF receptor-associated factor 6, E3 ubiquitin protein ligase; E3 ubiquitin ligase that, together with UBE2N and UBE2V1, mediates the synthesis of ’Lys-63’-linked-polyubiquitin chains conjugated to proteins, such as IKBKG, AKT1 and AKT2. Also mediates ubiquitination of free/unanchored polyubiquitin chain that leads to MAP3K7 activation. Leads to the activation of NF- kappa-B and JUN. May be essential for the formation of functional osteoclasts. Seems to also play a role in dendritic cells (DCs) maturation and/or activation. Represses c-Myb-mediated transactivation, in B-lymphocytes. Ad [...] | tripartite motif containing 44; May play a role in the process of differentiation and maturation of neuronal cells (By similarity). May regulate the activity of TRIM17 | 0.418 |
| TRAF6 | UBC | ENSP00000337853 | ENSP00000344818 | TNF receptor-associated factor 6, E3 ubiquitin protein ligase; E3 ubiquitin ligase that, together with UBE2N and UBE2V1, mediates the synthesis of ’Lys-63’-linked-polyubiquitin chains conjugated to proteins, such as IKBKG, AKT1 and AKT2. Also mediates ubiquitination of free/unanchored polyubiquitin chain that leads to MAP3K7 activation. Leads to the activation of NF- kappa-B and JUN. May be essential for the formation of functional osteoclasts. Seems to also play a role in dendritic cells (DCs) maturation and/or activation. Represses c-Myb-mediated transactivation, in B-lymphocytes. Ad [...] | ubiquitin C | 0.999 |
| TRAF6 | USP39 | ENSP00000337853 | ENSP00000312981 | TNF receptor-associated factor 6, E3 ubiquitin protein ligase; E3 ubiquitin ligase that, together with UBE2N and UBE2V1, mediates the synthesis of ’Lys-63’-linked-polyubiquitin chains conjugated to proteins, such as IKBKG, AKT1 and AKT2. Also mediates ubiquitination of free/unanchored polyubiquitin chain that leads to MAP3K7 activation. Leads to the activation of NF- kappa-B and JUN. May be essential for the formation of functional osteoclasts. Seems to also play a role in dendritic cells (DCs) maturation and/or activation. Represses c-Myb-mediated transactivation, in B-lymphocytes. Ad [...] | ubiquitin specific peptidase 39 | 0.426 |
| TRIM17 | BBOX1 | ENSP00000295033 | ENSP00000263182 | tripartite motif containing 17; May function as an ubiquitin E3 ligase | butyrobetaine (gamma), 2-oxoglutarate dioxygenase (gamma-butyrobetaine hydroxylase) 1; Catalyzes the formation of L-carnitine from gamma- butyrobetaine | 0.824 |
| TRIM17 | TRAF6 | ENSP00000295033 | ENSP00000337853 | tripartite motif containing 17; May function as an ubiquitin E3 ligase | TNF receptor-associated factor 6, E3 ubiquitin protein ligase; E3 ubiquitin ligase that, together with UBE2N and UBE2V1, mediates the synthesis of ’Lys-63’-linked-polyubiquitin chains conjugated to proteins, such as IKBKG, AKT1 and AKT2. Also mediates ubiquitination of free/unanchored polyubiquitin chain that leads to MAP3K7 activation. Leads to the activation of NF- kappa-B and JUN. May be essential for the formation of functional osteoclasts. Seems to also play a role in dendritic cells (DCs) maturation and/or activation. Represses c-Myb-mediated transactivation, in B-lymphocytes. Ad [...] | 0.524 |
| TRIM17 | TRIM44 | ENSP00000295033 | ENSP00000299413 | tripartite motif containing 17; May function as an ubiquitin E3 ligase | tripartite motif containing 44; May play a role in the process of differentiation and maturation of neuronal cells (By similarity). May regulate the activity of TRIM17 | 0.917 |
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