node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
CHURC1 | POLR2M | ENSP00000450144 | ENSP00000299638 | churchill domain containing 1; Transcriptional activator that mediates FGF signaling during neural development. Plays a role in the regulation of cell movement (By similarity). Does not bind DNA by itself | polymerase (RNA) II (DNA directed) polypeptide M | 0.452 |
MYZAP | POLR2M | ENSP00000267853 | ENSP00000299638 | myocardial zonula adherens protein | polymerase (RNA) II (DNA directed) polypeptide M | 0.542 |
POLR2E | POLR2M | ENSP00000215587 | ENSP00000299638 | polymerase (RNA) II (DNA directed) polypeptide E, 25kDa; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Common component of RNA polymerases I, II and III which synthesize ribosomal RNA precursors, mRNA precursors and many functional non-coding RNAs, and small RNAs, such as 5S rRNA and tRNAs, respectively. Pol II is the central component of the basal RNA polymerase II transcription machinery. Pols are composed of mobile elements that move relative to each other. In Pol II, POLR2E/RPB5 is part of the low [...] | polymerase (RNA) II (DNA directed) polypeptide M | 0.472 |
POLR2E | RPAP2 | ENSP00000215587 | ENSP00000359368 | polymerase (RNA) II (DNA directed) polypeptide E, 25kDa; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Common component of RNA polymerases I, II and III which synthesize ribosomal RNA precursors, mRNA precursors and many functional non-coding RNAs, and small RNAs, such as 5S rRNA and tRNAs, respectively. Pol II is the central component of the basal RNA polymerase II transcription machinery. Pols are composed of mobile elements that move relative to each other. In Pol II, POLR2E/RPB5 is part of the low [...] | RNA polymerase II associated protein 2; Protein phosphatase that displays CTD phosphatase activity and regulates transcription of snRNA genes. Recognizes and binds phosphorylated ’Ser-7’ of the C-terminal heptapeptide repeat domain (CTD) of the largest RNA polymerase II subunit POLR2A, and mediates dephosphorylation of ’Ser-5’ of the CTD, thereby promoting transcription of snRNA genes | 0.883 |
POLR2M | CHURC1 | ENSP00000299638 | ENSP00000450144 | polymerase (RNA) II (DNA directed) polypeptide M | churchill domain containing 1; Transcriptional activator that mediates FGF signaling during neural development. Plays a role in the regulation of cell movement (By similarity). Does not bind DNA by itself | 0.452 |
POLR2M | MYZAP | ENSP00000299638 | ENSP00000267853 | polymerase (RNA) II (DNA directed) polypeptide M | myocardial zonula adherens protein | 0.542 |
POLR2M | POLR2E | ENSP00000299638 | ENSP00000215587 | polymerase (RNA) II (DNA directed) polypeptide M | polymerase (RNA) II (DNA directed) polypeptide E, 25kDa; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Common component of RNA polymerases I, II and III which synthesize ribosomal RNA precursors, mRNA precursors and many functional non-coding RNAs, and small RNAs, such as 5S rRNA and tRNAs, respectively. Pol II is the central component of the basal RNA polymerase II transcription machinery. Pols are composed of mobile elements that move relative to each other. In Pol II, POLR2E/RPB5 is part of the low [...] | 0.472 |
POLR2M | RPAP2 | ENSP00000299638 | ENSP00000359368 | polymerase (RNA) II (DNA directed) polypeptide M | RNA polymerase II associated protein 2; Protein phosphatase that displays CTD phosphatase activity and regulates transcription of snRNA genes. Recognizes and binds phosphorylated ’Ser-7’ of the C-terminal heptapeptide repeat domain (CTD) of the largest RNA polymerase II subunit POLR2A, and mediates dephosphorylation of ’Ser-5’ of the CTD, thereby promoting transcription of snRNA genes | 0.418 |
POLR2M | RPRD2 | ENSP00000299638 | ENSP00000358064 | polymerase (RNA) II (DNA directed) polypeptide M | regulation of nuclear pre-mRNA domain containing 2 | 0.414 |
RPAP2 | POLR2E | ENSP00000359368 | ENSP00000215587 | RNA polymerase II associated protein 2; Protein phosphatase that displays CTD phosphatase activity and regulates transcription of snRNA genes. Recognizes and binds phosphorylated ’Ser-7’ of the C-terminal heptapeptide repeat domain (CTD) of the largest RNA polymerase II subunit POLR2A, and mediates dephosphorylation of ’Ser-5’ of the CTD, thereby promoting transcription of snRNA genes | polymerase (RNA) II (DNA directed) polypeptide E, 25kDa; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Common component of RNA polymerases I, II and III which synthesize ribosomal RNA precursors, mRNA precursors and many functional non-coding RNAs, and small RNAs, such as 5S rRNA and tRNAs, respectively. Pol II is the central component of the basal RNA polymerase II transcription machinery. Pols are composed of mobile elements that move relative to each other. In Pol II, POLR2E/RPB5 is part of the low [...] | 0.883 |
RPAP2 | POLR2M | ENSP00000359368 | ENSP00000299638 | RNA polymerase II associated protein 2; Protein phosphatase that displays CTD phosphatase activity and regulates transcription of snRNA genes. Recognizes and binds phosphorylated ’Ser-7’ of the C-terminal heptapeptide repeat domain (CTD) of the largest RNA polymerase II subunit POLR2A, and mediates dephosphorylation of ’Ser-5’ of the CTD, thereby promoting transcription of snRNA genes | polymerase (RNA) II (DNA directed) polypeptide M | 0.418 |
RPAP2 | RPRD2 | ENSP00000359368 | ENSP00000358064 | RNA polymerase II associated protein 2; Protein phosphatase that displays CTD phosphatase activity and regulates transcription of snRNA genes. Recognizes and binds phosphorylated ’Ser-7’ of the C-terminal heptapeptide repeat domain (CTD) of the largest RNA polymerase II subunit POLR2A, and mediates dephosphorylation of ’Ser-5’ of the CTD, thereby promoting transcription of snRNA genes | regulation of nuclear pre-mRNA domain containing 2 | 0.774 |
RPRD2 | POLR2M | ENSP00000358064 | ENSP00000299638 | regulation of nuclear pre-mRNA domain containing 2 | polymerase (RNA) II (DNA directed) polypeptide M | 0.414 |
RPRD2 | RPAP2 | ENSP00000358064 | ENSP00000359368 | regulation of nuclear pre-mRNA domain containing 2 | RNA polymerase II associated protein 2; Protein phosphatase that displays CTD phosphatase activity and regulates transcription of snRNA genes. Recognizes and binds phosphorylated ’Ser-7’ of the C-terminal heptapeptide repeat domain (CTD) of the largest RNA polymerase II subunit POLR2A, and mediates dephosphorylation of ’Ser-5’ of the CTD, thereby promoting transcription of snRNA genes | 0.774 |