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STRINGSTRING
MYZAP MYZAP POLR2E POLR2E POLR2M POLR2M CHURC1 CHURC1 RPAP2 RPAP2 RPRD2 RPRD2
"POLR2M" - polymerase in Homo sapiens
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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protein of unknown 3D structure
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some 3D structure is known or predicted
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query proteins and first shell of interactors
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second shell of interactors
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from curated databases
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experimentally determined
Predicted Interactions
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fusion edge
gene fusions
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gene co-occurrence
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textmining
coexpression edge
co-expression
homology edge
protein homology
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Score
POLR2Mpolymerase (RNA) II (DNA directed) polypeptide M (368 aa)    
Predicted Functional Partners:
MYZAP
myocardial zonula adherens protein (466 aa)
  score_image         score_image   0.542
POLR2E
polymerase (RNA) II (DNA directed) polypeptide E, 25kDa; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Common component of RNA polymerases I, II and III which synthesize ribosomal RNA precursors, mRNA precursors and many functional non-coding RNAs, and small RNAs, such as 5S rRNA and tRNAs, respectively. Pol II is the central component of the basal RNA polymerase II transcription machinery. Pols are composed of mobile elements that move relative to each other. In Pol II, POLR2E/RPB5 is part of the low [...] (210 aa)
            score_image   0.472
CHURC1
churchill domain containing 1; Transcriptional activator that mediates FGF signaling during neural development. Plays a role in the regulation of cell movement (By similarity). Does not bind DNA by itself (140 aa)
            score_image   0.452
RPAP2
RNA polymerase II associated protein 2; Protein phosphatase that displays CTD phosphatase activity and regulates transcription of snRNA genes. Recognizes and binds phosphorylated ’Ser-7’ of the C-terminal heptapeptide repeat domain (CTD) of the largest RNA polymerase II subunit POLR2A, and mediates dephosphorylation of ’Ser-5’ of the CTD, thereby promoting transcription of snRNA genes (612 aa)
            score_image   0.418
RPRD2
regulation of nuclear pre-mRNA domain containing 2 (1461 aa)
            score_image   0.414
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man
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