Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Size
small nodes:
protein of unknown 3D structure
protein of unknown 3D structure
large nodes:
some 3D structure is known or predicted
some 3D structure is known or predicted
Node Color
colored nodes:
query proteins and first shell of interactors
query proteins and first shell of interactors
white nodes:
second shell of interactors
second shell of interactors
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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Your Input:
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Neighborhood |
Gene Fusion |
Cooccurence |
Coexpression |
Experiments |
Databases |
Textmining |
[Homology] |
Score |
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 | COG1 | component of oligomeric golgi complex 1; Required for normal Golgi function (By similarity) (980 aa) | ||||||||||||
Predicted Functional Partners:
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 | COG3 | component of oligomeric golgi complex 3; Involved in ER-Golgi transport (828 aa) |
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0.999 | ||||||||
 | COG4 | component of oligomeric golgi complex 4; Required for normal Golgi function. Plays a role in SNARE-pin assembly and Golgi-to-ER retrograde transport via its interaction with SCFD1 (789 aa) |
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0.999 | ||||||||
 | COG2 | component of oligomeric golgi complex 2; Required for normal Golgi morphology and function (738 aa) |
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0.999 | |||||||
 | COG7 | component of oligomeric golgi complex 7; Required for normal Golgi function (By similarity) (770 aa) |
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0.999 | ||||||||
 | COG5 | component of oligomeric golgi complex 5; Required for normal Golgi function (By similarity) (860 aa) |
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0.999 | |||||||
 | COG8 | component of oligomeric golgi complex 8; Required for normal Golgi function (By similarity) (612 aa) |
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0.999 | |||||||
 | COG6 | component of oligomeric golgi complex 6; Required for normal Golgi function (By similarity) (657 aa) |
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0.999 | ||||||||
 | GOLGA3 | golgin A3; Golgi auto-antigen; probably involved in maintaining Golgi structure (1498 aa) |
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0.900 | ||||||||||
 | UBC | ubiquitin C (685 aa) |
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0.849 | ||||||||||
 | ENSG00000260371 | Uncharacterized protein (156 aa) |
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0.778 | ||||||||
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man
Other names: H. sapiens, Homo, Homo sapiens, human, man
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