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STRINGSTRING
OXSR1 OXSR1 HSH2D HSH2D SLFN5 SLFN5 UBC UBC TMEM125 TMEM125
"SLFN5" - schlafen family member 5 in Homo sapiens
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Size
small protein node
small nodes:
protein of unknown 3D structure
large protein node
large nodes:
some 3D structure is known or predicted
Node Color
colored protein node
colored nodes:
query proteins and first shell of interactors
non-colored protein node
white nodes:
second shell of interactors
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
database edge
from curated databases
experiment edge
experimentally determined
Predicted Interactions
neighborhood edge
gene neighborhood
fusion edge
gene fusions
cooccurrence edge
gene co-occurrence
Others
textmining edge
textmining
coexpression edge
co-expression
homology edge
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SLFN5schlafen family member 5; May have a role in hematopoietic cell differentiation (By similarity) (891 aa)    
Predicted Functional Partners:
UBC
ubiquitin C (685 aa)
        score_image       0.795
OXSR1
oxidative-stress responsive 1; Regulates downstream kinases in response to environmental stress. May also have a function in regulating the actin cytoskeleton (527 aa)
        score_image       0.644
TMEM125
transmembrane protein 125 (219 aa)
            score_image   0.457
HSH2D
hematopoietic SH2 domain containing; May be a modulator of the apoptotic response through its ability to affect mitochondrial stability (By similarity). Adapter protein involved in tyrosine kinase and CD28 signaling. Seems to affect CD28-mediated activation of the RE/AP element of the interleukin-2 promoter (352 aa)
            score_image   0.412
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man
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