node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ANKRD52 | CSRNP2 | ENSP00000267116 | ENSP00000228515 | ankyrin repeat domain 52; Putative regulatory subunit of protein phosphatase 6 (PP6) that may be involved in the recognition of phosphoprotein substrates | cysteine-serine-rich nuclear protein 2; Binds to the consensus sequence 5’-AGAGTG-3’ and has transcriptional activator activity (By similarity). May play a role in apoptosis | 0.503 |
ANKRD52 | SMCR7L | ENSP00000267116 | ENSP00000327124 | ankyrin repeat domain 52; Putative regulatory subunit of protein phosphatase 6 (PP6) that may be involved in the recognition of phosphoprotein substrates | Smith-Magenis syndrome chromosome region, candidate 7-like; Mitochondrial outer membrane protein which regulates mitochondrial morphology. Mitochondrial morphology is controlled by two opposites processes- fusion and fission. Seems to have a key role in inhibiting DNM1L-induced mitochondrial fission | 0.528 |
ANKRD52 | ZBTB39 | ENSP00000267116 | ENSP00000300101 | ankyrin repeat domain 52; Putative regulatory subunit of protein phosphatase 6 (PP6) that may be involved in the recognition of phosphoprotein substrates | zinc finger and BTB domain containing 39; May be involved in transcriptional regulation | 0.566 |
CNPY2 | DGKA | ENSP00000273308 | ENSP00000328405 | canopy 2 homolog (zebrafish); Positive regulator of neurite outgrowth by stabilizing myosin regulatory light chain (MRLC). It prevents MIR-mediated MRLC ubiquitination and its subsequent proteasomal degradation | diacylglycerol kinase, alpha 80kDa; Upon cell stimulation converts the second messenger diacylglycerol into phosphatidate, initiating the resynthesis of phosphatidylinositols and attenuating protein kinase C activity | 0.415 |
CNPY2 | PIP4K2C | ENSP00000273308 | ENSP00000347032 | canopy 2 homolog (zebrafish); Positive regulator of neurite outgrowth by stabilizing myosin regulatory light chain (MRLC). It prevents MIR-mediated MRLC ubiquitination and its subsequent proteasomal degradation | phosphatidylinositol-5-phosphate 4-kinase, type II, gamma; May play an important role in the production of Phosphatidylinositol bisphosphate (PIP2), in the endoplasmic reticulum (By similarity) | 0.477 |
CNPY2 | ZBTB39 | ENSP00000273308 | ENSP00000300101 | canopy 2 homolog (zebrafish); Positive regulator of neurite outgrowth by stabilizing myosin regulatory light chain (MRLC). It prevents MIR-mediated MRLC ubiquitination and its subsequent proteasomal degradation | zinc finger and BTB domain containing 39; May be involved in transcriptional regulation | 0.627 |
CSRNP2 | ANKRD52 | ENSP00000228515 | ENSP00000267116 | cysteine-serine-rich nuclear protein 2; Binds to the consensus sequence 5’-AGAGTG-3’ and has transcriptional activator activity (By similarity). May play a role in apoptosis | ankyrin repeat domain 52; Putative regulatory subunit of protein phosphatase 6 (PP6) that may be involved in the recognition of phosphoprotein substrates | 0.503 |
CSRNP2 | SMCR7L | ENSP00000228515 | ENSP00000327124 | cysteine-serine-rich nuclear protein 2; Binds to the consensus sequence 5’-AGAGTG-3’ and has transcriptional activator activity (By similarity). May play a role in apoptosis | Smith-Magenis syndrome chromosome region, candidate 7-like; Mitochondrial outer membrane protein which regulates mitochondrial morphology. Mitochondrial morphology is controlled by two opposites processes- fusion and fission. Seems to have a key role in inhibiting DNM1L-induced mitochondrial fission | 0.572 |
CSRNP2 | ZBTB39 | ENSP00000228515 | ENSP00000300101 | cysteine-serine-rich nuclear protein 2; Binds to the consensus sequence 5’-AGAGTG-3’ and has transcriptional activator activity (By similarity). May play a role in apoptosis | zinc finger and BTB domain containing 39; May be involved in transcriptional regulation | 0.590 |
DGKA | CNPY2 | ENSP00000328405 | ENSP00000273308 | diacylglycerol kinase, alpha 80kDa; Upon cell stimulation converts the second messenger diacylglycerol into phosphatidate, initiating the resynthesis of phosphatidylinositols and attenuating protein kinase C activity | canopy 2 homolog (zebrafish); Positive regulator of neurite outgrowth by stabilizing myosin regulatory light chain (MRLC). It prevents MIR-mediated MRLC ubiquitination and its subsequent proteasomal degradation | 0.415 |
DGKA | TMEM4 | ENSP00000328405 | ENSP00000446743 | diacylglycerol kinase, alpha 80kDa; Upon cell stimulation converts the second messenger diacylglycerol into phosphatidate, initiating the resynthesis of phosphatidylinositols and attenuating protein kinase C activity | Uncharacterized protein | 0.443 |
DGKA | ZBTB39 | ENSP00000328405 | ENSP00000300101 | diacylglycerol kinase, alpha 80kDa; Upon cell stimulation converts the second messenger diacylglycerol into phosphatidate, initiating the resynthesis of phosphatidylinositols and attenuating protein kinase C activity | zinc finger and BTB domain containing 39; May be involved in transcriptional regulation | 0.599 |
DGKB | ZBTB39 | ENSP00000382260 | ENSP00000300101 | diacylglycerol kinase, beta 90kDa | zinc finger and BTB domain containing 39; May be involved in transcriptional regulation | 0.548 |
DGKG | ZBTB39 | ENSP00000265022 | ENSP00000300101 | diacylglycerol kinase, gamma 90kDa; Reverses the normal flow of glycerolipid biosynthesis by phosphorylating diacylglycerol back to phosphatidic acid | zinc finger and BTB domain containing 39; May be involved in transcriptional regulation | 0.548 |
PIP4K2C | CNPY2 | ENSP00000347032 | ENSP00000273308 | phosphatidylinositol-5-phosphate 4-kinase, type II, gamma; May play an important role in the production of Phosphatidylinositol bisphosphate (PIP2), in the endoplasmic reticulum (By similarity) | canopy 2 homolog (zebrafish); Positive regulator of neurite outgrowth by stabilizing myosin regulatory light chain (MRLC). It prevents MIR-mediated MRLC ubiquitination and its subsequent proteasomal degradation | 0.477 |
PIP4K2C | TMEM4 | ENSP00000347032 | ENSP00000446743 | phosphatidylinositol-5-phosphate 4-kinase, type II, gamma; May play an important role in the production of Phosphatidylinositol bisphosphate (PIP2), in the endoplasmic reticulum (By similarity) | Uncharacterized protein | 0.528 |
PIP4K2C | ZBTB39 | ENSP00000347032 | ENSP00000300101 | phosphatidylinositol-5-phosphate 4-kinase, type II, gamma; May play an important role in the production of Phosphatidylinositol bisphosphate (PIP2), in the endoplasmic reticulum (By similarity) | zinc finger and BTB domain containing 39; May be involved in transcriptional regulation | 0.673 |
SMCR7L | ANKRD52 | ENSP00000327124 | ENSP00000267116 | Smith-Magenis syndrome chromosome region, candidate 7-like; Mitochondrial outer membrane protein which regulates mitochondrial morphology. Mitochondrial morphology is controlled by two opposites processes- fusion and fission. Seems to have a key role in inhibiting DNM1L-induced mitochondrial fission | ankyrin repeat domain 52; Putative regulatory subunit of protein phosphatase 6 (PP6) that may be involved in the recognition of phosphoprotein substrates | 0.528 |
SMCR7L | CSRNP2 | ENSP00000327124 | ENSP00000228515 | Smith-Magenis syndrome chromosome region, candidate 7-like; Mitochondrial outer membrane protein which regulates mitochondrial morphology. Mitochondrial morphology is controlled by two opposites processes- fusion and fission. Seems to have a key role in inhibiting DNM1L-induced mitochondrial fission | cysteine-serine-rich nuclear protein 2; Binds to the consensus sequence 5’-AGAGTG-3’ and has transcriptional activator activity (By similarity). May play a role in apoptosis | 0.572 |
SMCR7L | ZBTB39 | ENSP00000327124 | ENSP00000300101 | Smith-Magenis syndrome chromosome region, candidate 7-like; Mitochondrial outer membrane protein which regulates mitochondrial morphology. Mitochondrial morphology is controlled by two opposites processes- fusion and fission. Seems to have a key role in inhibiting DNM1L-induced mitochondrial fission | zinc finger and BTB domain containing 39; May be involved in transcriptional regulation | 0.647 |