Full Link:
  • Version:
  • 10.0 (archived version)
STRINGSTRING
DGKB DGKB TMEM4 TMEM4 SMCR7L SMCR7L ANKRD52 ANKRD52 PIP4K2C PIP4K2C DGKA DGKA ZBTB39 ZBTB39 CSRNP2 CSRNP2 CNPY2 CNPY2 XRN1 XRN1 DGKG DGKG
"ZBTB39" - zinc finger and BTB domain containing 39 in Homo sapiens
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Size
small protein node
small nodes:
protein of unknown 3D structure
large protein node
large nodes:
some 3D structure is known or predicted
Node Color
colored protein node
colored nodes:
query proteins and first shell of interactors
non-colored protein node
white nodes:
second shell of interactors
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
database edge
from curated databases
experiment edge
experimentally determined
Predicted Interactions
neighborhood edge
gene neighborhood
fusion edge
gene fusions
cooccurrence edge
gene co-occurrence
Others
textmining edge
textmining
coexpression edge
co-expression
homology edge
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ZBTB39zinc finger and BTB domain containing 39; May be involved in transcriptional regulation (712 aa)    
Predicted Functional Partners:
TMEM4
Uncharacterized protein (263 aa)
      score_image     score_image   0.697
PIP4K2C
phosphatidylinositol-5-phosphate 4-kinase, type II, gamma; May play an important role in the production of Phosphatidylinositol bisphosphate (PIP2), in the endoplasmic reticulum (By similarity) (421 aa)
        score_image   score_image   0.673
SMCR7L
Smith-Magenis syndrome chromosome region, candidate 7-like; Mitochondrial outer membrane protein which regulates mitochondrial morphology. Mitochondrial morphology is controlled by two opposites processes- fusion and fission. Seems to have a key role in inhibiting DNM1L-induced mitochondrial fission (463 aa)
            score_image   0.647
CNPY2
canopy 2 homolog (zebrafish); Positive regulator of neurite outgrowth by stabilizing myosin regulatory light chain (MRLC). It prevents MIR-mediated MRLC ubiquitination and its subsequent proteasomal degradation (182 aa)
            score_image   0.627
DGKA
diacylglycerol kinase, alpha 80kDa; Upon cell stimulation converts the second messenger diacylglycerol into phosphatidate, initiating the resynthesis of phosphatidylinositols and attenuating protein kinase C activity (735 aa)
      score_image     score_image   0.599
CSRNP2
cysteine-serine-rich nuclear protein 2; Binds to the consensus sequence 5’-AGAGTG-3’ and has transcriptional activator activity (By similarity). May play a role in apoptosis (543 aa)
            score_image   0.590
ANKRD52
ankyrin repeat domain 52; Putative regulatory subunit of protein phosphatase 6 (PP6) that may be involved in the recognition of phosphoprotein substrates (1076 aa)
        score_image   score_image   0.566
DGKB
diacylglycerol kinase, beta 90kDa (804 aa)
      score_image     score_image   0.548
DGKG
diacylglycerol kinase, gamma 90kDa; Reverses the normal flow of glycerolipid biosynthesis by phosphorylating diacylglycerol back to phosphatidic acid (791 aa)
      score_image     score_image   0.548
XRN1
5’-3’ exoribonuclease 1; Major 5’-3’ exoribonuclease involved in mRNA decay. Required for the 5’-3’-processing of the G4 tetraplex-containing DNA and RNA substrates. The kinetic of hydrolysis is faster for G4 RNA tetraplex than for G4 DNA tetraplex and monomeric RNA tetraplex. Binds to RNA and DNA (By similarity). Plays a role in replication-dependent histone mRNA degradation. May act as a tumor suppressor protein in osteogenic sarcoma (OGS) (1706 aa)
      score_image score_image   score_image   0.543
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man
Server load: low (26%)