NAT16 protein (Homo sapiens) - STRING network view

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NAT16

N-acetyltransferase 16 (GCN5-related, putative) (369 aa)

Predicted Functional Partners:

C7orf43

0.823

NOD2

0.574

RIPK2

0.574

AP1S1

0.563

PSG8

0.480

AP1S2

0.400

Your Current Organism:

Homo sapiens

NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AP1S1	AP1S2	ENSP00000336666	ENSP00000328789	adaptor-related protein complex 1, sigma 1 subunit; Subunit of clathrin-associated adaptor protein complex 1 that plays a role in protein sorting in the late-Golgi/trans-Golgi network (TGN) and/or endosomes. The AP complexes mediate both the recruitment of clathrin to membranes and the recognition of sorting signals within the cytosolic tails of transmembrane cargo molecules	adaptor-related protein complex 1, sigma 2 subunit; Subunit of clathrin-associated adaptor protein complex 1 that plays a role in protein sorting in the late-Golgi/trans-Golgi network (TGN) and/or endosomes. The AP complexes mediate both the recruitment of clathrin to membranes and the recognition of sorting signals within the cytosolic tails of transmembrane cargo molecules	0.943
AP1S1	C7orf43	ENSP00000336666	ENSP00000324741	adaptor-related protein complex 1, sigma 1 subunit; Subunit of clathrin-associated adaptor protein complex 1 that plays a role in protein sorting in the late-Golgi/trans-Golgi network (TGN) and/or endosomes. The AP complexes mediate both the recruitment of clathrin to membranes and the recognition of sorting signals within the cytosolic tails of transmembrane cargo molecules	chromosome 7 open reading frame 43	0.581
AP1S1	NAT16	ENSP00000336666	ENSP00000300303	adaptor-related protein complex 1, sigma 1 subunit; Subunit of clathrin-associated adaptor protein complex 1 that plays a role in protein sorting in the late-Golgi/trans-Golgi network (TGN) and/or endosomes. The AP complexes mediate both the recruitment of clathrin to membranes and the recognition of sorting signals within the cytosolic tails of transmembrane cargo molecules	N-acetyltransferase 16 (GCN5-related, putative)	0.563
AP1S2	AP1S1	ENSP00000328789	ENSP00000336666	adaptor-related protein complex 1, sigma 2 subunit; Subunit of clathrin-associated adaptor protein complex 1 that plays a role in protein sorting in the late-Golgi/trans-Golgi network (TGN) and/or endosomes. The AP complexes mediate both the recruitment of clathrin to membranes and the recognition of sorting signals within the cytosolic tails of transmembrane cargo molecules	adaptor-related protein complex 1, sigma 1 subunit; Subunit of clathrin-associated adaptor protein complex 1 that plays a role in protein sorting in the late-Golgi/trans-Golgi network (TGN) and/or endosomes. The AP complexes mediate both the recruitment of clathrin to membranes and the recognition of sorting signals within the cytosolic tails of transmembrane cargo molecules	0.943
AP1S2	NAT16	ENSP00000328789	ENSP00000300303	adaptor-related protein complex 1, sigma 2 subunit; Subunit of clathrin-associated adaptor protein complex 1 that plays a role in protein sorting in the late-Golgi/trans-Golgi network (TGN) and/or endosomes. The AP complexes mediate both the recruitment of clathrin to membranes and the recognition of sorting signals within the cytosolic tails of transmembrane cargo molecules	N-acetyltransferase 16 (GCN5-related, putative)	0.400
C7orf43	AP1S1	ENSP00000324741	ENSP00000336666	chromosome 7 open reading frame 43	adaptor-related protein complex 1, sigma 1 subunit; Subunit of clathrin-associated adaptor protein complex 1 that plays a role in protein sorting in the late-Golgi/trans-Golgi network (TGN) and/or endosomes. The AP complexes mediate both the recruitment of clathrin to membranes and the recognition of sorting signals within the cytosolic tails of transmembrane cargo molecules	0.581
C7orf43	NAT16	ENSP00000324741	ENSP00000300303	chromosome 7 open reading frame 43	N-acetyltransferase 16 (GCN5-related, putative)	0.823
NAT16	AP1S1	ENSP00000300303	ENSP00000336666	N-acetyltransferase 16 (GCN5-related, putative)	adaptor-related protein complex 1, sigma 1 subunit; Subunit of clathrin-associated adaptor protein complex 1 that plays a role in protein sorting in the late-Golgi/trans-Golgi network (TGN) and/or endosomes. The AP complexes mediate both the recruitment of clathrin to membranes and the recognition of sorting signals within the cytosolic tails of transmembrane cargo molecules	0.563
NAT16	AP1S2	ENSP00000300303	ENSP00000328789	N-acetyltransferase 16 (GCN5-related, putative)	adaptor-related protein complex 1, sigma 2 subunit; Subunit of clathrin-associated adaptor protein complex 1 that plays a role in protein sorting in the late-Golgi/trans-Golgi network (TGN) and/or endosomes. The AP complexes mediate both the recruitment of clathrin to membranes and the recognition of sorting signals within the cytosolic tails of transmembrane cargo molecules	0.400
NAT16	C7orf43	ENSP00000300303	ENSP00000324741	N-acetyltransferase 16 (GCN5-related, putative)	chromosome 7 open reading frame 43	0.823
NAT16	NOD2	ENSP00000300303	ENSP00000300589	N-acetyltransferase 16 (GCN5-related, putative)	nucleotide-binding oligomerization domain containing 2; Induces NF-kappa-B via RICK (CARDIAK, RIP2) and IKK- gamma. Confers responsiveness to intracellular bacterial lipopolysaccharides (LPS)	0.574
NAT16	PSG8	ENSP00000300303	ENSP00000305005	N-acetyltransferase 16 (GCN5-related, putative)	pregnancy specific beta-1-glycoprotein 8	0.480
NAT16	RIPK2	ENSP00000300303	ENSP00000220751	N-acetyltransferase 16 (GCN5-related, putative)	receptor-interacting serine-threonine kinase 2; Serine/threonine/tyrosine kinase that plays an essential role in modulation of innate and adaptive immune responses. Upon stimulation by bacterial peptidoglycans, NOD1 and NOD2 are activated, oligomerize and recruit RIPK2 through CARD-CARD domains. Once recruited, RIPK2 autophosphorylates and undergoes ’Lys-63’-linked polyubiquitination by E3 ubiquitin ligases BIRC2 and BIRC3. The polyubiquitinated protein mediates the recruitment of MAP3K7/TAK1 to IKBKG/NEMO and induces ’Lys-63’-linked polyubiquitination of IKBKG/NEMO and subsequent acti [...]	0.574
NOD2	NAT16	ENSP00000300589	ENSP00000300303	nucleotide-binding oligomerization domain containing 2; Induces NF-kappa-B via RICK (CARDIAK, RIP2) and IKK- gamma. Confers responsiveness to intracellular bacterial lipopolysaccharides (LPS)	N-acetyltransferase 16 (GCN5-related, putative)	0.574
NOD2	RIPK2	ENSP00000300589	ENSP00000220751	nucleotide-binding oligomerization domain containing 2; Induces NF-kappa-B via RICK (CARDIAK, RIP2) and IKK- gamma. Confers responsiveness to intracellular bacterial lipopolysaccharides (LPS)	receptor-interacting serine-threonine kinase 2; Serine/threonine/tyrosine kinase that plays an essential role in modulation of innate and adaptive immune responses. Upon stimulation by bacterial peptidoglycans, NOD1 and NOD2 are activated, oligomerize and recruit RIPK2 through CARD-CARD domains. Once recruited, RIPK2 autophosphorylates and undergoes ’Lys-63’-linked polyubiquitination by E3 ubiquitin ligases BIRC2 and BIRC3. The polyubiquitinated protein mediates the recruitment of MAP3K7/TAK1 to IKBKG/NEMO and induces ’Lys-63’-linked polyubiquitination of IKBKG/NEMO and subsequent acti [...]	0.999
PSG8	NAT16	ENSP00000305005	ENSP00000300303	pregnancy specific beta-1-glycoprotein 8	N-acetyltransferase 16 (GCN5-related, putative)	0.480
RIPK2	NAT16	ENSP00000220751	ENSP00000300303	receptor-interacting serine-threonine kinase 2; Serine/threonine/tyrosine kinase that plays an essential role in modulation of innate and adaptive immune responses. Upon stimulation by bacterial peptidoglycans, NOD1 and NOD2 are activated, oligomerize and recruit RIPK2 through CARD-CARD domains. Once recruited, RIPK2 autophosphorylates and undergoes ’Lys-63’-linked polyubiquitination by E3 ubiquitin ligases BIRC2 and BIRC3. The polyubiquitinated protein mediates the recruitment of MAP3K7/TAK1 to IKBKG/NEMO and induces ’Lys-63’-linked polyubiquitination of IKBKG/NEMO and subsequent acti [...]	N-acetyltransferase 16 (GCN5-related, putative)	0.574
RIPK2	NOD2	ENSP00000220751	ENSP00000300589	receptor-interacting serine-threonine kinase 2; Serine/threonine/tyrosine kinase that plays an essential role in modulation of innate and adaptive immune responses. Upon stimulation by bacterial peptidoglycans, NOD1 and NOD2 are activated, oligomerize and recruit RIPK2 through CARD-CARD domains. Once recruited, RIPK2 autophosphorylates and undergoes ’Lys-63’-linked polyubiquitination by E3 ubiquitin ligases BIRC2 and BIRC3. The polyubiquitinated protein mediates the recruitment of MAP3K7/TAK1 to IKBKG/NEMO and induces ’Lys-63’-linked polyubiquitination of IKBKG/NEMO and subsequent acti [...]	nucleotide-binding oligomerization domain containing 2; Induces NF-kappa-B via RICK (CARDIAK, RIP2) and IKK- gamma. Confers responsiveness to intracellular bacterial lipopolysaccharides (LPS)	0.999

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