GNG8 protein (Homo sapiens) - STRING network view

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GNG8

guanine nucleotide binding protein (G protein), gamma 8; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein- effector interaction (70 aa)

Predicted Functional Partners:

GNB1

0.970

GNB2

0.968

GNB4

0.964

GNGT1

0.932

ADCY3

0.924

GNG11

0.922

ADCY8

0.921

GNAS

0.911

GNGT2

0.909

ADCY1

0.907

Your Current Organism:

Homo sapiens

NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ADCY1	ADCY3	ENSP00000297323	ENSP00000260600	adenylate cyclase 1 (brain); This is a calmodulin-sensitive adenylyl cyclase. May be involved in regulatory processes in the central nervous system. It may play a role in memory acquisition and learning	adenylate cyclase 3; Mediates odorant detection (possibly) via modulation of intracellular cAMP concentration	0.911
ADCY1	ADCY8	ENSP00000297323	ENSP00000286355	adenylate cyclase 1 (brain); This is a calmodulin-sensitive adenylyl cyclase. May be involved in regulatory processes in the central nervous system. It may play a role in memory acquisition and learning	adenylate cyclase 8 (brain); This is a membrane-bound, calcium-stimulable adenylyl cyclase. May be involved in learning, in memory and in drug dependence (By similarity)	0.910
ADCY1	GNAS	ENSP00000297323	ENSP00000360141	adenylate cyclase 1 (brain); This is a calmodulin-sensitive adenylyl cyclase. May be involved in regulatory processes in the central nervous system. It may play a role in memory acquisition and learning	GNAS complex locus; Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems. The G(s) protein is involved in hormonal regulation of adenylate cyclase- it activates the cyclase in response to beta-adrenergic stimuli. XLas isoforms interact with the same set of receptors as Gnas isoforms (By similarity)	0.961
ADCY1	GNB1	ENSP00000297323	ENSP00000367869	adenylate cyclase 1 (brain); This is a calmodulin-sensitive adenylyl cyclase. May be involved in regulatory processes in the central nervous system. It may play a role in memory acquisition and learning	guanine nucleotide binding protein (G protein), beta polypeptide 1; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein- effector interaction	0.950
ADCY1	GNB2	ENSP00000297323	ENSP00000305260	adenylate cyclase 1 (brain); This is a calmodulin-sensitive adenylyl cyclase. May be involved in regulatory processes in the central nervous system. It may play a role in memory acquisition and learning	guanine nucleotide binding protein (G protein), beta polypeptide 2; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein- effector interaction	0.925
ADCY1	GNB4	ENSP00000297323	ENSP00000232564	adenylate cyclase 1 (brain); This is a calmodulin-sensitive adenylyl cyclase. May be involved in regulatory processes in the central nervous system. It may play a role in memory acquisition and learning	guanine nucleotide binding protein (G protein), beta polypeptide 4; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein- effector interaction	0.925
ADCY1	GNG11	ENSP00000297323	ENSP00000248564	adenylate cyclase 1 (brain); This is a calmodulin-sensitive adenylyl cyclase. May be involved in regulatory processes in the central nervous system. It may play a role in memory acquisition and learning	guanine nucleotide binding protein (G protein), gamma 11; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein- effector interaction (By similarity)	0.900
ADCY1	GNG8	ENSP00000297323	ENSP00000300873	adenylate cyclase 1 (brain); This is a calmodulin-sensitive adenylyl cyclase. May be involved in regulatory processes in the central nervous system. It may play a role in memory acquisition and learning	guanine nucleotide binding protein (G protein), gamma 8; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein- effector interaction	0.907
ADCY1	GNGT1	ENSP00000297323	ENSP00000248572	adenylate cyclase 1 (brain); This is a calmodulin-sensitive adenylyl cyclase. May be involved in regulatory processes in the central nervous system. It may play a role in memory acquisition and learning	guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 1; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein- effector interaction (By similarity)	0.900
ADCY3	ADCY1	ENSP00000260600	ENSP00000297323	adenylate cyclase 3; Mediates odorant detection (possibly) via modulation of intracellular cAMP concentration	adenylate cyclase 1 (brain); This is a calmodulin-sensitive adenylyl cyclase. May be involved in regulatory processes in the central nervous system. It may play a role in memory acquisition and learning	0.911
ADCY3	ADCY8	ENSP00000260600	ENSP00000286355	adenylate cyclase 3; Mediates odorant detection (possibly) via modulation of intracellular cAMP concentration	adenylate cyclase 8 (brain); This is a membrane-bound, calcium-stimulable adenylyl cyclase. May be involved in learning, in memory and in drug dependence (By similarity)	0.909
ADCY3	GNAS	ENSP00000260600	ENSP00000360141	adenylate cyclase 3; Mediates odorant detection (possibly) via modulation of intracellular cAMP concentration	GNAS complex locus; Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems. The G(s) protein is involved in hormonal regulation of adenylate cyclase- it activates the cyclase in response to beta-adrenergic stimuli. XLas isoforms interact with the same set of receptors as Gnas isoforms (By similarity)	0.922
ADCY3	GNB1	ENSP00000260600	ENSP00000367869	adenylate cyclase 3; Mediates odorant detection (possibly) via modulation of intracellular cAMP concentration	guanine nucleotide binding protein (G protein), beta polypeptide 1; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein- effector interaction	0.930
ADCY3	GNB2	ENSP00000260600	ENSP00000305260	adenylate cyclase 3; Mediates odorant detection (possibly) via modulation of intracellular cAMP concentration	guanine nucleotide binding protein (G protein), beta polypeptide 2; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein- effector interaction	0.925
ADCY3	GNB4	ENSP00000260600	ENSP00000232564	adenylate cyclase 3; Mediates odorant detection (possibly) via modulation of intracellular cAMP concentration	guanine nucleotide binding protein (G protein), beta polypeptide 4; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein- effector interaction	0.925
ADCY3	GNG11	ENSP00000260600	ENSP00000248564	adenylate cyclase 3; Mediates odorant detection (possibly) via modulation of intracellular cAMP concentration	guanine nucleotide binding protein (G protein), gamma 11; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein- effector interaction (By similarity)	0.900
ADCY3	GNG8	ENSP00000260600	ENSP00000300873	adenylate cyclase 3; Mediates odorant detection (possibly) via modulation of intracellular cAMP concentration	guanine nucleotide binding protein (G protein), gamma 8; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein- effector interaction	0.924
ADCY3	GNGT1	ENSP00000260600	ENSP00000248572	adenylate cyclase 3; Mediates odorant detection (possibly) via modulation of intracellular cAMP concentration	guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 1; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein- effector interaction (By similarity)	0.800
ADCY3	GNGT2	ENSP00000260600	ENSP00000300406	adenylate cyclase 3; Mediates odorant detection (possibly) via modulation of intracellular cAMP concentration	guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 2; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein- effector interaction (By similarity)	0.814
ADCY8	ADCY1	ENSP00000286355	ENSP00000297323	adenylate cyclase 8 (brain); This is a membrane-bound, calcium-stimulable adenylyl cyclase. May be involved in learning, in memory and in drug dependence (By similarity)	adenylate cyclase 1 (brain); This is a calmodulin-sensitive adenylyl cyclase. May be involved in regulatory processes in the central nervous system. It may play a role in memory acquisition and learning	0.910

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