LALBA protein (Homo sapiens) - STRING network view

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LALBA

lactalbumin, alpha-; Regulatory subunit of lactose synthase, changes the substrate specificity of galactosyltransferase in the mammary gland making glucose a good acceptor substrate for this enzyme. This enables LS to synthesize lactose, the major carbohydrate component of milk. In other tissues, galactosyltransferase transfers galactose onto the N-acetylglucosamine of the oligosaccharide chains in glycoproteins (142 aa)

Predicted Functional Partners:

B4GALT1

0.955

GALE

0.909

GALT

0.900

GLB1

0.900

LCT

0.900

ALB

0.766

MB

0.748

OR8S1

0.700

HSPA8

0.687

UBC

0.665

Your Current Organism:

Homo sapiens

NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ALB	GALE	ENSP00000295897	ENSP00000363621	albumin	UDP-galactose-4-epimerase; Catalyzes two distinct but analogous reactions- the epimerization of UDP-glucose to UDP-galactose and the epimerization of UDP-N-acetylglucosamine to UDP-N- acetylgalactosamine	0.459
ALB	GLB1	ENSP00000295897	ENSP00000306920	albumin	galactosidase, beta 1; Cleaves beta-linked terminal galactosyl residues from gangliosides, glycoproteins, and glycosaminoglycans	0.452
ALB	HSPA8	ENSP00000295897	ENSP00000227378	albumin	heat shock 70kDa protein 8; Acts as a repressor of transcriptional activation. Inhibits the transcriptional coactivator activity of CITED1 on Smad-mediated transcription. Chaperone. Component of the PRP19- CDC5L complex that forms an integral part of the spliceosome and is required for activating pre-mRNA splicing. May have a scaffolding role in the spliceosome assembly as it contacts all other components of the core complex	0.539
ALB	LALBA	ENSP00000295897	ENSP00000301046	albumin	lactalbumin, alpha-; Regulatory subunit of lactose synthase, changes the substrate specificity of galactosyltransferase in the mammary gland making glucose a good acceptor substrate for this enzyme. This enables LS to synthesize lactose, the major carbohydrate component of milk. In other tissues, galactosyltransferase transfers galactose onto the N-acetylglucosamine of the oligosaccharide chains in glycoproteins	0.766
ALB	LCT	ENSP00000295897	ENSP00000264162	albumin	lactase; LPH splits lactose in the small intestine	0.509
ALB	MB	ENSP00000295897	ENSP00000352835	albumin	myoglobin; Serves as a reserve supply of oxygen and facilitates the movement of oxygen within muscles (By similarity)	0.970
ALB	UBC	ENSP00000295897	ENSP00000344818	albumin	ubiquitin C	0.905
B4GALT1	GALE	ENSP00000369055	ENSP00000363621	UDP-Gal-betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 1	UDP-galactose-4-epimerase; Catalyzes two distinct but analogous reactions- the epimerization of UDP-glucose to UDP-galactose and the epimerization of UDP-N-acetylglucosamine to UDP-N- acetylgalactosamine	0.900
B4GALT1	GALT	ENSP00000369055	ENSP00000368119	UDP-Gal-betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 1	galactose-1-phosphate uridylyltransferase	0.900
B4GALT1	GLB1	ENSP00000369055	ENSP00000306920	UDP-Gal-betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 1	galactosidase, beta 1; Cleaves beta-linked terminal galactosyl residues from gangliosides, glycoproteins, and glycosaminoglycans	0.912
B4GALT1	LALBA	ENSP00000369055	ENSP00000301046	UDP-Gal-betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 1	lactalbumin, alpha-; Regulatory subunit of lactose synthase, changes the substrate specificity of galactosyltransferase in the mammary gland making glucose a good acceptor substrate for this enzyme. This enables LS to synthesize lactose, the major carbohydrate component of milk. In other tissues, galactosyltransferase transfers galactose onto the N-acetylglucosamine of the oligosaccharide chains in glycoproteins	0.955
B4GALT1	LCT	ENSP00000369055	ENSP00000264162	UDP-Gal-betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 1	lactase; LPH splits lactose in the small intestine	0.900
B4GALT1	UBC	ENSP00000369055	ENSP00000344818	UDP-Gal-betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 1	ubiquitin C	0.620
GALE	ALB	ENSP00000363621	ENSP00000295897	UDP-galactose-4-epimerase; Catalyzes two distinct but analogous reactions- the epimerization of UDP-glucose to UDP-galactose and the epimerization of UDP-N-acetylglucosamine to UDP-N- acetylgalactosamine	albumin	0.459
GALE	B4GALT1	ENSP00000363621	ENSP00000369055	UDP-galactose-4-epimerase; Catalyzes two distinct but analogous reactions- the epimerization of UDP-glucose to UDP-galactose and the epimerization of UDP-N-acetylglucosamine to UDP-N- acetylgalactosamine	UDP-Gal-betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 1	0.900
GALE	GALT	ENSP00000363621	ENSP00000368119	UDP-galactose-4-epimerase; Catalyzes two distinct but analogous reactions- the epimerization of UDP-glucose to UDP-galactose and the epimerization of UDP-N-acetylglucosamine to UDP-N- acetylgalactosamine	galactose-1-phosphate uridylyltransferase	0.999
GALE	LALBA	ENSP00000363621	ENSP00000301046	UDP-galactose-4-epimerase; Catalyzes two distinct but analogous reactions- the epimerization of UDP-glucose to UDP-galactose and the epimerization of UDP-N-acetylglucosamine to UDP-N- acetylgalactosamine	lactalbumin, alpha-; Regulatory subunit of lactose synthase, changes the substrate specificity of galactosyltransferase in the mammary gland making glucose a good acceptor substrate for this enzyme. This enables LS to synthesize lactose, the major carbohydrate component of milk. In other tissues, galactosyltransferase transfers galactose onto the N-acetylglucosamine of the oligosaccharide chains in glycoproteins	0.909
GALE	LCT	ENSP00000363621	ENSP00000264162	UDP-galactose-4-epimerase; Catalyzes two distinct but analogous reactions- the epimerization of UDP-glucose to UDP-galactose and the epimerization of UDP-N-acetylglucosamine to UDP-N- acetylgalactosamine	lactase; LPH splits lactose in the small intestine	0.422
GALE	UBC	ENSP00000363621	ENSP00000344818	UDP-galactose-4-epimerase; Catalyzes two distinct but analogous reactions- the epimerization of UDP-glucose to UDP-galactose and the epimerization of UDP-N-acetylglucosamine to UDP-N- acetylgalactosamine	ubiquitin C	0.893
GALT	B4GALT1	ENSP00000368119	ENSP00000369055	galactose-1-phosphate uridylyltransferase	UDP-Gal-betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 1	0.900

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