ANKRD33 protein (Homo sapiens) - STRING network view

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Size

small nodes:
protein of unknown 3D structure

large nodes:
some 3D structure is known or predicted

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

ANKRD33

ankyrin repeat domain 33 (452 aa)

Predicted Functional Partners:

USP36

0.740

USP49

0.740

PPP6C

0.629

TPRXL

0.499

RTP2

0.457

Your Current Organism:

Homo sapiens

NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but resolution at 400 dpi

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as simple tabular text output:

download

TSV: tab separated values - can be opened in Excel

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and annotated functions of the network proteins

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ANKRD33	PPP6C	ENSP00000301190	ENSP00000392147	ankyrin repeat domain 33	protein phosphatase 6, catalytic subunit; Catalytic subunit of protein phosphatase 6 (PP6). PP6 is a component of a signaling pathway regulating cell cycle progression in response to IL2 receptor stimulation. N-terminal domain restricts G1 to S phase progression in cancer cells, in part through control of cyclin D1. Downregulates MAP3K7 kinase activation of the IL1 signaling pathway by dephosphorylation of MAP3K7	0.629
ANKRD33	RTP2	ENSP00000301190	ENSP00000350976	ankyrin repeat domain 33	receptor (chemosensory) transporter protein 2; Specifically promotes functional cell surface expression of olfactory receptors, but not of other GPCRs (By similarity)	0.457
ANKRD33	TPRXL	ENSP00000301190	ENSP00000322097	ankyrin repeat domain 33	tetra-peptide repeat homeobox-like	0.499
ANKRD33	USP36	ENSP00000301190	ENSP00000310590	ankyrin repeat domain 33	ubiquitin specific peptidase 36; May be required for maintaining multiple types of adult stem cells. May function as a transcriptional repressor by continually deubiquiting histone H2B at the promoters of genes critical for cellular differentiation, thereby preventing histone H3 ’Lys-4’ trimethylation (H3K4) (By similarity)	0.740
ANKRD33	USP49	ENSP00000301190	ENSP00000297229	ankyrin repeat domain 33	ubiquitin specific peptidase 49	0.740
PPP6C	ANKRD33	ENSP00000392147	ENSP00000301190	protein phosphatase 6, catalytic subunit; Catalytic subunit of protein phosphatase 6 (PP6). PP6 is a component of a signaling pathway regulating cell cycle progression in response to IL2 receptor stimulation. N-terminal domain restricts G1 to S phase progression in cancer cells, in part through control of cyclin D1. Downregulates MAP3K7 kinase activation of the IL1 signaling pathway by dephosphorylation of MAP3K7	ankyrin repeat domain 33	0.629
RTP2	ANKRD33	ENSP00000350976	ENSP00000301190	receptor (chemosensory) transporter protein 2; Specifically promotes functional cell surface expression of olfactory receptors, but not of other GPCRs (By similarity)	ankyrin repeat domain 33	0.457
RTP2	TPRXL	ENSP00000350976	ENSP00000322097	receptor (chemosensory) transporter protein 2; Specifically promotes functional cell surface expression of olfactory receptors, but not of other GPCRs (By similarity)	tetra-peptide repeat homeobox-like	0.501
TPRXL	ANKRD33	ENSP00000322097	ENSP00000301190	tetra-peptide repeat homeobox-like	ankyrin repeat domain 33	0.499
TPRXL	RTP2	ENSP00000322097	ENSP00000350976	tetra-peptide repeat homeobox-like	receptor (chemosensory) transporter protein 2; Specifically promotes functional cell surface expression of olfactory receptors, but not of other GPCRs (By similarity)	0.501
USP36	ANKRD33	ENSP00000310590	ENSP00000301190	ubiquitin specific peptidase 36; May be required for maintaining multiple types of adult stem cells. May function as a transcriptional repressor by continually deubiquiting histone H2B at the promoters of genes critical for cellular differentiation, thereby preventing histone H3 ’Lys-4’ trimethylation (H3K4) (By similarity)	ankyrin repeat domain 33	0.740
USP36	USP49	ENSP00000310590	ENSP00000297229	ubiquitin specific peptidase 36; May be required for maintaining multiple types of adult stem cells. May function as a transcriptional repressor by continually deubiquiting histone H2B at the promoters of genes critical for cellular differentiation, thereby preventing histone H3 ’Lys-4’ trimethylation (H3K4) (By similarity)	ubiquitin specific peptidase 49	0.406
USP49	ANKRD33	ENSP00000297229	ENSP00000301190	ubiquitin specific peptidase 49	ankyrin repeat domain 33	0.740
USP49	USP36	ENSP00000297229	ENSP00000310590	ubiquitin specific peptidase 49	ubiquitin specific peptidase 36; May be required for maintaining multiple types of adult stem cells. May function as a transcriptional repressor by continually deubiquiting histone H2B at the promoters of genes critical for cellular differentiation, thereby preventing histone H3 ’Lys-4’ trimethylation (H3K4) (By similarity)	0.406

Experiments

Cooccurrence

Textmining

Neighborhood

Databases

Fusion

Coexpression

© STRING Consortium 2017

Credits

Access

Info

About