Full Link:
  • Version:
  • 10.0 (archived version)
STRINGSTRING
ABCB1 ABCB1 ABCC1 ABCC1 MVP MVP ABCC4 ABCC4 ABCG2 ABCG2 C19orf48 C19orf48 MRPS7 MRPS7 ABCC2 ABCC2 ABCC3 ABCC3 ABCC5 ABCC5
"C19orf48" - chromosome 19 open reading frame 48 in Homo sapiens
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Size
small protein node
small nodes:
protein of unknown 3D structure
large protein node
large nodes:
some 3D structure is known or predicted
Node Color
colored protein node
colored nodes:
query proteins and first shell of interactors
non-colored protein node
white nodes:
second shell of interactors
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
database edge
from curated databases
experiment edge
experimentally determined
Predicted Interactions
neighborhood edge
gene neighborhood
fusion edge
gene fusions
cooccurrence edge
gene co-occurrence
Others
textmining edge
textmining
coexpression edge
co-expression
homology edge
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
C19orf48chromosome 19 open reading frame 48 (117 aa)    
Predicted Functional Partners:
ABCB1
ATP-binding cassette, sub-family B (MDR/TAP), member 1; Energy-dependent efflux pump responsible for decreased drug accumulation in multidrug-resistant cells (1280 aa)
            score_image   0.720
ABCC1
ATP-binding cassette, sub-family C (CFTR/MRP), member 1 (1531 aa)
            score_image   0.658
MVP
major vault protein; Required for normal vault structure. Vaults are multi- subunit structures that may act as scaffolds for proteins involved in signal transduction. Vaults may also play a role in nucleo- cytoplasmic transport. Down-regulates INFG-mediated STAT1 signaling and subsequent activation of JAK. Down-regulates SRC activity and signaling through MAP kinases (893 aa)
            score_image   0.650
ABCC2
ATP-binding cassette, sub-family C (CFTR/MRP), member 2; Mediates hepatobiliary excretion of numerous organic anions. May function as a cellular cisplatin transporter (1545 aa)
            score_image   0.567
ABCG2
ATP-binding cassette, sub-family G (WHITE), member 2 (655 aa)
            score_image   0.538
ABCC4
ATP-binding cassette, sub-family C (CFTR/MRP), member 4; May be an organic anion pump relevant to cellular detoxification (1325 aa)
            score_image   0.504
ABCC3
ATP-binding cassette, sub-family C (CFTR/MRP), member 3 (1527 aa)
            score_image   0.480
ABCC5
ATP-binding cassette, sub-family C (CFTR/MRP), member 5 (1437 aa)
            score_image   0.472
MRPS7
mitochondrial ribosomal protein S7 (242 aa)
            score_image   0.472
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man
Server load: medium (47%)