node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
CDA | DCTD | ENSP00000364212 | ENSP00000349576 | cytidine deaminase; This enzyme scavenge exogenous and endogenous cytidine and 2’-deoxycytidine for UMP synthesis | dCMP deaminase; Supplies the nucleotide substrate for thymidylate synthetase | 0.833 |
CDA | TK1 | ENSP00000364212 | ENSP00000301634 | cytidine deaminase; This enzyme scavenge exogenous and endogenous cytidine and 2’-deoxycytidine for UMP synthesis | thymidine kinase 1, soluble | 0.924 |
CDA | TYMP | ENSP00000364212 | ENSP00000252029 | cytidine deaminase; This enzyme scavenge exogenous and endogenous cytidine and 2’-deoxycytidine for UMP synthesis | thymidine phosphorylase; May have a role in maintaining the integrity of the blood vessels. Has growth promoting activity on endothelial cells, angiogenic activity in vivo and chemotactic activity on endothelial cells in vitro | 0.987 |
CDA | TYMS | ENSP00000364212 | ENSP00000315644 | cytidine deaminase; This enzyme scavenge exogenous and endogenous cytidine and 2’-deoxycytidine for UMP synthesis | thymidylate synthetase; Contributes to the de novo mitochondrial thymidylate biosynthesis pathway | 0.552 |
CDA | UBC | ENSP00000364212 | ENSP00000344818 | cytidine deaminase; This enzyme scavenge exogenous and endogenous cytidine and 2’-deoxycytidine for UMP synthesis | ubiquitin C | 0.515 |
CDA | UPP1 | ENSP00000364212 | ENSP00000330032 | cytidine deaminase; This enzyme scavenge exogenous and endogenous cytidine and 2’-deoxycytidine for UMP synthesis | uridine phosphorylase 1; Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis | 0.980 |
CDK1 | DUT | ENSP00000378699 | ENSP00000370376 | cyclin-dependent kinase 1; Plays a key role in the control of the eukaryotic cell cycle by modulating the centrosome cycle as well as mitotic onset; promotes G2-M transition, and regulates G1 progress and G1-S transition via association with multiple interphase cyclins. Required in higher cells for entry into S-phase and mitosis. Phosphorylates PARVA/actopaxin, APC, AMPH, APC, BARD1, Bcl- xL/BCL2L1, BRCA2, CALD1, CASP8, CDC7, CDC20, CDC25A, CDC25C, CC2D1A, CSNK2 proteins/CKII, FZR1/CDH1, CDK7, CEBPB, CHAMP1, DMD/dystrophin, EEF1 proteins/EF-1, EZH2, KIF11/EG5, EGFR, FANCG, FOS, GFAP, G [...] | deoxyuridine triphosphatase | 0.833 |
CDK1 | TK1 | ENSP00000378699 | ENSP00000301634 | cyclin-dependent kinase 1; Plays a key role in the control of the eukaryotic cell cycle by modulating the centrosome cycle as well as mitotic onset; promotes G2-M transition, and regulates G1 progress and G1-S transition via association with multiple interphase cyclins. Required in higher cells for entry into S-phase and mitosis. Phosphorylates PARVA/actopaxin, APC, AMPH, APC, BARD1, Bcl- xL/BCL2L1, BRCA2, CALD1, CASP8, CDC7, CDC20, CDC25A, CDC25C, CC2D1A, CSNK2 proteins/CKII, FZR1/CDH1, CDK7, CEBPB, CHAMP1, DMD/dystrophin, EEF1 proteins/EF-1, EZH2, KIF11/EG5, EGFR, FANCG, FOS, GFAP, G [...] | thymidine kinase 1, soluble | 0.956 |
CDK1 | TYMS | ENSP00000378699 | ENSP00000315644 | cyclin-dependent kinase 1; Plays a key role in the control of the eukaryotic cell cycle by modulating the centrosome cycle as well as mitotic onset; promotes G2-M transition, and regulates G1 progress and G1-S transition via association with multiple interphase cyclins. Required in higher cells for entry into S-phase and mitosis. Phosphorylates PARVA/actopaxin, APC, AMPH, APC, BARD1, Bcl- xL/BCL2L1, BRCA2, CALD1, CASP8, CDC7, CDC20, CDC25A, CDC25C, CC2D1A, CSNK2 proteins/CKII, FZR1/CDH1, CDK7, CEBPB, CHAMP1, DMD/dystrophin, EEF1 proteins/EF-1, EZH2, KIF11/EG5, EGFR, FANCG, FOS, GFAP, G [...] | thymidylate synthetase; Contributes to the de novo mitochondrial thymidylate biosynthesis pathway | 0.973 |
CDK1 | UBC | ENSP00000378699 | ENSP00000344818 | cyclin-dependent kinase 1; Plays a key role in the control of the eukaryotic cell cycle by modulating the centrosome cycle as well as mitotic onset; promotes G2-M transition, and regulates G1 progress and G1-S transition via association with multiple interphase cyclins. Required in higher cells for entry into S-phase and mitosis. Phosphorylates PARVA/actopaxin, APC, AMPH, APC, BARD1, Bcl- xL/BCL2L1, BRCA2, CALD1, CASP8, CDC7, CDC20, CDC25A, CDC25C, CC2D1A, CSNK2 proteins/CKII, FZR1/CDH1, CDK7, CEBPB, CHAMP1, DMD/dystrophin, EEF1 proteins/EF-1, EZH2, KIF11/EG5, EGFR, FANCG, FOS, GFAP, G [...] | ubiquitin C | 0.999 |
DCTD | CDA | ENSP00000349576 | ENSP00000364212 | dCMP deaminase; Supplies the nucleotide substrate for thymidylate synthetase | cytidine deaminase; This enzyme scavenge exogenous and endogenous cytidine and 2’-deoxycytidine for UMP synthesis | 0.833 |
DCTD | DTYMK | ENSP00000349576 | ENSP00000304802 | dCMP deaminase; Supplies the nucleotide substrate for thymidylate synthetase | deoxythymidylate kinase (thymidylate kinase); Catalyzes the conversion of dTMP to dTDP | 0.966 |
DCTD | DUT | ENSP00000349576 | ENSP00000370376 | dCMP deaminase; Supplies the nucleotide substrate for thymidylate synthetase | deoxyuridine triphosphatase | 0.970 |
DCTD | TK1 | ENSP00000349576 | ENSP00000301634 | dCMP deaminase; Supplies the nucleotide substrate for thymidylate synthetase | thymidine kinase 1, soluble | 0.950 |
DCTD | TYMP | ENSP00000349576 | ENSP00000252029 | dCMP deaminase; Supplies the nucleotide substrate for thymidylate synthetase | thymidine phosphorylase; May have a role in maintaining the integrity of the blood vessels. Has growth promoting activity on endothelial cells, angiogenic activity in vivo and chemotactic activity on endothelial cells in vitro | 0.404 |
DCTD | TYMS | ENSP00000349576 | ENSP00000315644 | dCMP deaminase; Supplies the nucleotide substrate for thymidylate synthetase | thymidylate synthetase; Contributes to the de novo mitochondrial thymidylate biosynthesis pathway | 0.977 |
DCTD | UBC | ENSP00000349576 | ENSP00000344818 | dCMP deaminase; Supplies the nucleotide substrate for thymidylate synthetase | ubiquitin C | 0.483 |
DTYMK | DCTD | ENSP00000304802 | ENSP00000349576 | deoxythymidylate kinase (thymidylate kinase); Catalyzes the conversion of dTMP to dTDP | dCMP deaminase; Supplies the nucleotide substrate for thymidylate synthetase | 0.966 |
DTYMK | DUT | ENSP00000304802 | ENSP00000370376 | deoxythymidylate kinase (thymidylate kinase); Catalyzes the conversion of dTMP to dTDP | deoxyuridine triphosphatase | 0.979 |
DTYMK | TK1 | ENSP00000304802 | ENSP00000301634 | deoxythymidylate kinase (thymidylate kinase); Catalyzes the conversion of dTMP to dTDP | thymidine kinase 1, soluble | 0.969 |