LGALS4 protein (Homo sapiens) - STRING network view

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LGALS4

lectin, galactoside-binding, soluble, 4; Galectin that binds lactose and a related range of sugars. May be involved in the assembly of adherens junctions (323 aa)

Predicted Functional Partners:

ELAVL4

0.834

ELAVL2

0.822

ERBB3

0.821

CCNB1

0.820

NOTUM

0.818

ELAVL3

0.817

ELAVL1

0.814

CSF2RA

0.812

HOXB7

0.806

BCKDHB

0.705

Your Current Organism:

Homo sapiens

NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
BCKDHB	LGALS4	ENSP00000318351	ENSP00000302100	branched chain keto acid dehydrogenase E1, beta polypeptide; The branched-chain alpha-keto dehydrogenase complex catalyzes the overall conversion of alpha-keto acids to acyl-CoA and CO(2). It contains multiple copies of three enzymatic components- branched-chain alpha-keto acid decarboxylase (E1), lipoamide acyltransferase (E2) and lipoamide dehydrogenase (E3)	lectin, galactoside-binding, soluble, 4; Galectin that binds lactose and a related range of sugars. May be involved in the assembly of adherens junctions	0.705
CCNB1	ELAVL1	ENSP00000256442	ENSP00000385269	cyclin B1; Essential for the control of the cell cycle at the G2/M (mitosis) transition	ELAV (embryonic lethal, abnormal vision, Drosophila)-like 1 (Hu antigen R); Involved in 3’-UTR ARE-mediated MYC stabilization. Binds avidly to the AU-rich element in FOS and IL3/interleukin-3 mRNAs. In the case of the FOS AU-rich element, HUR binds to a core element of 27 nucleotides that contain AUUUA, AUUUUA and AUUUUUA motifs. Binds preferentially to the 5’-UUUU[AG]UUU-3’ motif in vitro	0.510
CCNB1	LGALS4	ENSP00000256442	ENSP00000302100	cyclin B1; Essential for the control of the cell cycle at the G2/M (mitosis) transition	lectin, galactoside-binding, soluble, 4; Galectin that binds lactose and a related range of sugars. May be involved in the assembly of adherens junctions	0.820
CSF2RA	ELAVL1	ENSP00000394227	ENSP00000385269	colony stimulating factor 2 receptor, alpha, low-affinity (granulocyte-macrophage)	ELAV (embryonic lethal, abnormal vision, Drosophila)-like 1 (Hu antigen R); Involved in 3’-UTR ARE-mediated MYC stabilization. Binds avidly to the AU-rich element in FOS and IL3/interleukin-3 mRNAs. In the case of the FOS AU-rich element, HUR binds to a core element of 27 nucleotides that contain AUUUA, AUUUUA and AUUUUUA motifs. Binds preferentially to the 5’-UUUU[AG]UUU-3’ motif in vitro	0.724
CSF2RA	ELAVL2	ENSP00000394227	ENSP00000369460	colony stimulating factor 2 receptor, alpha, low-affinity (granulocyte-macrophage)	ELAV (embryonic lethal, abnormal vision, Drosophila)-like 2 (Hu antigen B); Binds RNA. Seems to recognize a GAAA motif. Can bind to its own 3’-UTR, the FOS 3’-UTR and the ID 3’-UTR	0.729
CSF2RA	ELAVL3	ENSP00000394227	ENSP00000352162	colony stimulating factor 2 receptor, alpha, low-affinity (granulocyte-macrophage)	ELAV (embryonic lethal, abnormal vision, Drosophila)-like 3 (Hu antigen C); Binds to AU-rich sequences (AREs) of target mRNAs, including VEGF mRNA. May also bind poly-A tracts via RRM 3 (By similarity). May be involved in neuronal differentiation and maintenance	0.727
CSF2RA	ELAVL4	ENSP00000394227	ENSP00000349594	colony stimulating factor 2 receptor, alpha, low-affinity (granulocyte-macrophage)	ELAV (embryonic lethal, abnormal vision, Drosophila)-like 4; May play a role in neuron-specific RNA processing. Protects CDKN1A mRNA from decay by binding to its 3’-UTR (By similarity). Binds to AU-rich sequences (AREs) of target mRNAs, including VEGF and FOS mRNA	0.753
CSF2RA	LGALS4	ENSP00000394227	ENSP00000302100	colony stimulating factor 2 receptor, alpha, low-affinity (granulocyte-macrophage)	lectin, galactoside-binding, soluble, 4; Galectin that binds lactose and a related range of sugars. May be involved in the assembly of adherens junctions	0.812
CSF2RA	NOTUM	ENSP00000394227	ENSP00000387310	colony stimulating factor 2 receptor, alpha, low-affinity (granulocyte-macrophage)	notum pectinacetylesterase homolog (Drosophila); May deacetylate GlcNAc residues on cell surface glycans (Potential)	0.566
ELAVL1	CCNB1	ENSP00000385269	ENSP00000256442	ELAV (embryonic lethal, abnormal vision, Drosophila)-like 1 (Hu antigen R); Involved in 3’-UTR ARE-mediated MYC stabilization. Binds avidly to the AU-rich element in FOS and IL3/interleukin-3 mRNAs. In the case of the FOS AU-rich element, HUR binds to a core element of 27 nucleotides that contain AUUUA, AUUUUA and AUUUUUA motifs. Binds preferentially to the 5’-UUUU[AG]UUU-3’ motif in vitro	cyclin B1; Essential for the control of the cell cycle at the G2/M (mitosis) transition	0.510
ELAVL1	CSF2RA	ENSP00000385269	ENSP00000394227	ELAV (embryonic lethal, abnormal vision, Drosophila)-like 1 (Hu antigen R); Involved in 3’-UTR ARE-mediated MYC stabilization. Binds avidly to the AU-rich element in FOS and IL3/interleukin-3 mRNAs. In the case of the FOS AU-rich element, HUR binds to a core element of 27 nucleotides that contain AUUUA, AUUUUA and AUUUUUA motifs. Binds preferentially to the 5’-UUUU[AG]UUU-3’ motif in vitro	colony stimulating factor 2 receptor, alpha, low-affinity (granulocyte-macrophage)	0.724
ELAVL1	LGALS4	ENSP00000385269	ENSP00000302100	ELAV (embryonic lethal, abnormal vision, Drosophila)-like 1 (Hu antigen R); Involved in 3’-UTR ARE-mediated MYC stabilization. Binds avidly to the AU-rich element in FOS and IL3/interleukin-3 mRNAs. In the case of the FOS AU-rich element, HUR binds to a core element of 27 nucleotides that contain AUUUA, AUUUUA and AUUUUUA motifs. Binds preferentially to the 5’-UUUU[AG]UUU-3’ motif in vitro	lectin, galactoside-binding, soluble, 4; Galectin that binds lactose and a related range of sugars. May be involved in the assembly of adherens junctions	0.814
ELAVL1	NOTUM	ENSP00000385269	ENSP00000387310	ELAV (embryonic lethal, abnormal vision, Drosophila)-like 1 (Hu antigen R); Involved in 3’-UTR ARE-mediated MYC stabilization. Binds avidly to the AU-rich element in FOS and IL3/interleukin-3 mRNAs. In the case of the FOS AU-rich element, HUR binds to a core element of 27 nucleotides that contain AUUUA, AUUUUA and AUUUUUA motifs. Binds preferentially to the 5’-UUUU[AG]UUU-3’ motif in vitro	notum pectinacetylesterase homolog (Drosophila); May deacetylate GlcNAc residues on cell surface glycans (Potential)	0.593
ELAVL2	CSF2RA	ENSP00000369460	ENSP00000394227	ELAV (embryonic lethal, abnormal vision, Drosophila)-like 2 (Hu antigen B); Binds RNA. Seems to recognize a GAAA motif. Can bind to its own 3’-UTR, the FOS 3’-UTR and the ID 3’-UTR	colony stimulating factor 2 receptor, alpha, low-affinity (granulocyte-macrophage)	0.729
ELAVL2	ELAVL3	ENSP00000369460	ENSP00000352162	ELAV (embryonic lethal, abnormal vision, Drosophila)-like 2 (Hu antigen B); Binds RNA. Seems to recognize a GAAA motif. Can bind to its own 3’-UTR, the FOS 3’-UTR and the ID 3’-UTR	ELAV (embryonic lethal, abnormal vision, Drosophila)-like 3 (Hu antigen C); Binds to AU-rich sequences (AREs) of target mRNAs, including VEGF mRNA. May also bind poly-A tracts via RRM 3 (By similarity). May be involved in neuronal differentiation and maintenance	0.622
ELAVL2	ELAVL4	ENSP00000369460	ENSP00000349594	ELAV (embryonic lethal, abnormal vision, Drosophila)-like 2 (Hu antigen B); Binds RNA. Seems to recognize a GAAA motif. Can bind to its own 3’-UTR, the FOS 3’-UTR and the ID 3’-UTR	ELAV (embryonic lethal, abnormal vision, Drosophila)-like 4; May play a role in neuron-specific RNA processing. Protects CDKN1A mRNA from decay by binding to its 3’-UTR (By similarity). Binds to AU-rich sequences (AREs) of target mRNAs, including VEGF and FOS mRNA	0.593
ELAVL2	LGALS4	ENSP00000369460	ENSP00000302100	ELAV (embryonic lethal, abnormal vision, Drosophila)-like 2 (Hu antigen B); Binds RNA. Seems to recognize a GAAA motif. Can bind to its own 3’-UTR, the FOS 3’-UTR and the ID 3’-UTR	lectin, galactoside-binding, soluble, 4; Galectin that binds lactose and a related range of sugars. May be involved in the assembly of adherens junctions	0.822
ELAVL2	NOTUM	ENSP00000369460	ENSP00000387310	ELAV (embryonic lethal, abnormal vision, Drosophila)-like 2 (Hu antigen B); Binds RNA. Seems to recognize a GAAA motif. Can bind to its own 3’-UTR, the FOS 3’-UTR and the ID 3’-UTR	notum pectinacetylesterase homolog (Drosophila); May deacetylate GlcNAc residues on cell surface glycans (Potential)	0.608
ELAVL3	CSF2RA	ENSP00000352162	ENSP00000394227	ELAV (embryonic lethal, abnormal vision, Drosophila)-like 3 (Hu antigen C); Binds to AU-rich sequences (AREs) of target mRNAs, including VEGF mRNA. May also bind poly-A tracts via RRM 3 (By similarity). May be involved in neuronal differentiation and maintenance	colony stimulating factor 2 receptor, alpha, low-affinity (granulocyte-macrophage)	0.727
ELAVL3	ELAVL2	ENSP00000352162	ENSP00000369460	ELAV (embryonic lethal, abnormal vision, Drosophila)-like 3 (Hu antigen C); Binds to AU-rich sequences (AREs) of target mRNAs, including VEGF mRNA. May also bind poly-A tracts via RRM 3 (By similarity). May be involved in neuronal differentiation and maintenance	ELAV (embryonic lethal, abnormal vision, Drosophila)-like 2 (Hu antigen B); Binds RNA. Seems to recognize a GAAA motif. Can bind to its own 3’-UTR, the FOS 3’-UTR and the ID 3’-UTR	0.622

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