node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ATP1B3 | SMR3B | ENSP00000286371 | ENSP00000302400 | ATPase, Na+/K+ transporting, beta 3 polypeptide; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. The exact function of the beta-3 subunit is not known | submaxillary gland androgen regulated protein 3B | 0.542 |
ATP2A2 | SMR3B | ENSP00000440045 | ENSP00000302400 | ATPase, Ca++ transporting, cardiac muscle, slow twitch 2; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the translocation of calcium from the cytosol to the sarcoplasmic reticulum lumen. Isoform 2 is involved in the regulation of the contraction/relaxation cycle | submaxillary gland androgen regulated protein 3B | 0.604 |
HTN1 | MUC7 | ENSP00000246896 | ENSP00000302021 | histatin 1; Histatins are salivary proteins that are considered to be major precursors of the protective proteinaceous structure on tooth surfaces (enamel pellicle). In addition, histatins exhibit antibacterial and antifungal activities | mucin 7, secreted; May function in a protective capacity by promoting the clearance of bacteria in the oral cavity and aiding in mastication, speech, and swallowing. Binds P.aeruginosa pili | 0.739 |
HTN1 | SMR3B | ENSP00000246896 | ENSP00000302400 | histatin 1; Histatins are salivary proteins that are considered to be major precursors of the protective proteinaceous structure on tooth surfaces (enamel pellicle). In addition, histatins exhibit antibacterial and antifungal activities | submaxillary gland androgen regulated protein 3B | 0.476 |
KIAA0368 | SMR3B | ENSP00000259335 | ENSP00000302400 | KIAA0368; Adapter/scaffolding protein that binds to the 26S proteasome, motor proteins and other compartment specific proteins. May couple the proteasome to different compartments including endosome, endoplasmic reticulum and centrosome. May play a role in ERAD and other enhanced proteolyis | submaxillary gland androgen regulated protein 3B | 0.604 |
KIAA1279 | SMR3B | ENSP00000354848 | ENSP00000302400 | KIAA1279; Required for organization of axonal microtubules, and axonal outgrowth and maintenance during peripheral and central nervous system development. Regulates mitochondrial transport by modulating KIF1B motor activity | submaxillary gland androgen regulated protein 3B | 0.463 |
MUC7 | HTN1 | ENSP00000302021 | ENSP00000246896 | mucin 7, secreted; May function in a protective capacity by promoting the clearance of bacteria in the oral cavity and aiding in mastication, speech, and swallowing. Binds P.aeruginosa pili | histatin 1; Histatins are salivary proteins that are considered to be major precursors of the protective proteinaceous structure on tooth surfaces (enamel pellicle). In addition, histatins exhibit antibacterial and antifungal activities | 0.739 |
MUC7 | SMR3B | ENSP00000302021 | ENSP00000302400 | mucin 7, secreted; May function in a protective capacity by promoting the clearance of bacteria in the oral cavity and aiding in mastication, speech, and swallowing. Binds P.aeruginosa pili | submaxillary gland androgen regulated protein 3B | 0.647 |
NUP188 | SMR3B | ENSP00000361658 | ENSP00000302400 | nucleoporin 188kDa; May function as a component of the nuclear pore complex (NPC) | submaxillary gland androgen regulated protein 3B | 0.604 |
PROL1 | SMR3B | ENSP00000382485 | ENSP00000302400 | proline rich, lacrimal 1; Opiorphin is an endogenous inhibitor of neprilysin and aminopeptidase N. Inhibits the breakdown of substance P, Mca-BK2 and Met-enkephalin by neprilysin in vitro with IC(50) values of 29 uM, 33 uM and 33 uM respectively. Inhibits the breakdown of Ala- pNA by aminopeptidase N in vitro with an IC(50) of 65 uM. Has a potent analgesic effect when administered to rats by intravenous injection | submaxillary gland androgen regulated protein 3B | 0.508 |
SMR3B | ATP1B3 | ENSP00000302400 | ENSP00000286371 | submaxillary gland androgen regulated protein 3B | ATPase, Na+/K+ transporting, beta 3 polypeptide; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. The exact function of the beta-3 subunit is not known | 0.542 |
SMR3B | ATP2A2 | ENSP00000302400 | ENSP00000440045 | submaxillary gland androgen regulated protein 3B | ATPase, Ca++ transporting, cardiac muscle, slow twitch 2; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the translocation of calcium from the cytosol to the sarcoplasmic reticulum lumen. Isoform 2 is involved in the regulation of the contraction/relaxation cycle | 0.604 |
SMR3B | HTN1 | ENSP00000302400 | ENSP00000246896 | submaxillary gland androgen regulated protein 3B | histatin 1; Histatins are salivary proteins that are considered to be major precursors of the protective proteinaceous structure on tooth surfaces (enamel pellicle). In addition, histatins exhibit antibacterial and antifungal activities | 0.476 |
SMR3B | KIAA0368 | ENSP00000302400 | ENSP00000259335 | submaxillary gland androgen regulated protein 3B | KIAA0368; Adapter/scaffolding protein that binds to the 26S proteasome, motor proteins and other compartment specific proteins. May couple the proteasome to different compartments including endosome, endoplasmic reticulum and centrosome. May play a role in ERAD and other enhanced proteolyis | 0.604 |
SMR3B | KIAA1279 | ENSP00000302400 | ENSP00000354848 | submaxillary gland androgen regulated protein 3B | KIAA1279; Required for organization of axonal microtubules, and axonal outgrowth and maintenance during peripheral and central nervous system development. Regulates mitochondrial transport by modulating KIF1B motor activity | 0.463 |
SMR3B | MUC7 | ENSP00000302400 | ENSP00000302021 | submaxillary gland androgen regulated protein 3B | mucin 7, secreted; May function in a protective capacity by promoting the clearance of bacteria in the oral cavity and aiding in mastication, speech, and swallowing. Binds P.aeruginosa pili | 0.647 |
SMR3B | NUP188 | ENSP00000302400 | ENSP00000361658 | submaxillary gland androgen regulated protein 3B | nucleoporin 188kDa; May function as a component of the nuclear pore complex (NPC) | 0.604 |
SMR3B | PROL1 | ENSP00000302400 | ENSP00000382485 | submaxillary gland androgen regulated protein 3B | proline rich, lacrimal 1; Opiorphin is an endogenous inhibitor of neprilysin and aminopeptidase N. Inhibits the breakdown of substance P, Mca-BK2 and Met-enkephalin by neprilysin in vitro with IC(50) values of 29 uM, 33 uM and 33 uM respectively. Inhibits the breakdown of Ala- pNA by aminopeptidase N in vitro with an IC(50) of 65 uM. Has a potent analgesic effect when administered to rats by intravenous injection | 0.508 |
SMR3B | TNPO2 | ENSP00000302400 | ENSP00000407182 | submaxillary gland androgen regulated protein 3B | transportin 2; Probably functions in nuclear protein import as nuclear transport receptor. Serves as receptor for nuclear localization signals (NLS) in cargo substrates. Is thought to mediate docking of the importin/substrate complex to the nuclear pore complex (NPC) through binding to nucleoporin and the complex is subsequently translocated through the pore by an energy requiring, Ran-dependent mechanism. At the nucleoplasmic side of the NPC, Ran binds to the importin, the importin/substrate complex dissociates and importin is re-exported from the nucleus to the cytoplasm where GTP hy [...] | 0.542 |
SMR3B | USO1 | ENSP00000302400 | ENSP00000440586 | submaxillary gland androgen regulated protein 3B | USO1 vesicle docking protein homolog (yeast); General vesicular transport factor required for intercisternal transport in the Golgi stack; it is required for transcytotic fusion and/or subsequent binding of the vesicles to the target membrane. May well act as a vesicular anchor by interacting with the target membrane and holding the vesicular and target membranes in proximity (By similarity) | 0.463 |