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STRINGSTRING
PCCB PCCB GPR176 GPR176 EIF4E3 EIF4E3 TMEM106B TMEM106B WDR44 WDR44 GPR27 GPR27 GPR101 GPR101 GPR61 GPR61 GPR62 GPR62 GPR135 GPR135 GPR52 GPR52
"GPR27" - G protein-coupled receptor 27 in Homo sapiens
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Size
small protein node
small nodes:
protein of unknown 3D structure
large protein node
large nodes:
some 3D structure is known or predicted
Node Color
colored protein node
colored nodes:
query proteins and first shell of interactors
non-colored protein node
white nodes:
second shell of interactors
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
database edge
from curated databases
experiment edge
experimentally determined
Predicted Interactions
neighborhood edge
gene neighborhood
fusion edge
gene fusions
cooccurrence edge
gene co-occurrence
Others
textmining edge
textmining
coexpression edge
co-expression
homology edge
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
GPR27G protein-coupled receptor 27; Orphan receptor. Possible candidate for amine-like G- protein coupled receptor (375 aa)    
Predicted Functional Partners:
GPR176
G protein-coupled receptor 176; Orphan receptor (515 aa)
            score_image   0.680
GPR61
G protein-coupled receptor 61; Orphan receptor (451 aa)
            score_image   0.596
WDR44
WD repeat domain 44 (913 aa)
            score_image   0.582
GPR62
G protein-coupled receptor 62; Orphan receptor (368 aa)
            score_image   0.570
EIF4E3
eukaryotic translation initiation factor 4E family member 3; Recognizes and binds the 7-methylguanosine-containing mRNA cap during an early step in the initiation of protein synthesis. May act as an inhibitor of EIF4E1 activity (By similarity) (224 aa)
            score_image   0.564
GPR101
G protein-coupled receptor 101; Orphan receptor (508 aa)
            score_image   0.560
GPR135
G protein-coupled receptor 135; Orphan receptor (494 aa)
            score_image   0.554
TMEM106B
transmembrane protein 106B (274 aa)
            score_image   0.497
PCCB
propionyl CoA carboxylase, beta polypeptide (559 aa)
            score_image   0.485
GPR52
G protein-coupled receptor 52; Orphan receptor (361 aa)
            score_image   0.479
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man
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